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本專欄列出權威醫學期刊中經過同行評議（同儕審查）的文章，提供的證據支持各種醫療情況下避免異體輸血的臨床策略的使用。
聯繫我們
搜尋
採用多手段、多學科和個體化的方法
Care of the injured Jehovah's Witness patient: case report and review of the literature.
Trauma surgery.
Traumatically injured Jehovah's Witnesses: a sixteen-year experience of treatment and transfusion dilemmas at a level I trauma center.
Emergency subtotal colectomy in a Jehovah's Witness with massive lower gastrointestinal bleeding: challenges encountered and lessons learned.
Clinical strategies in the medical care of Jehovah's Witnesses.
Reducing blood loss in a burn care unit: a review of its key determinants.
Jehovah's Witnesses: unique problems in a unique trauma population.
院前
Guidelines for prehospital fluid resuscitation in the injured patient.
Pre-hospital haemostatic dressings: a systematic review.
Prehospital intravenous fluid administration is associated with higher mortality in trauma patients: a National Trauma Data Bank analysis.
Does increased prehospital replacement volume lead to a poor clinical course and an increased mortality? A matched-pair analysis of 1896 patients of the Trauma Registry of the German Society for Trauma Surgery who were managed by an emergency doctor at the accident site.
Tourniquet use in the civilian prehospital setting.
Early prehospital tranexamic acid following injury is associated with a 30-day survival benefit: A secondary analysis of a randomized clinical trial.
Scoop and run to the trauma center or stay and play at the local hospital: hospital transfer's effect on mortality.
Prehospital tranexamic acid for severe trauma.
Is advanced life support better than basic life support in prehospital care? A systematic review.
Prehospital interventions for penetrating trauma victims: a prospective comparison between Advanced Life Support and Basic Life Support.
Effect of low-dose supplementation of arginine vasopressin on need for blood product transfusions in patients with trauma and hemorrhagic shock: a randomized clinical trial.
A balanced approach to tourniquet use: lessons learned and relearned.
積極控制出血
休克的管理
快速送到醫院
抗凝管理和逆轉
Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.
Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors.
Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents.
Emergency reversal of warfarin anticoagulation.
Management of anticoagulation agents in trauma patients.
Idarucizumab for dabigatran reversal - full cohort analysis.
Reversal of clopidogrel-induced bleeding with rFVIIa in healthy subjects: a randomized, placebo-controlled, double-blind, exploratory study.
Rapid warfarin reversal in the setting of intracranial hemorrhage: a comparison of plasma, recombinant activated factor VII, and prothrombin complex concentrate.
迅速施行動脈栓塞或機械性血流阻斷
Selective angiographic embolization of blunt splenic traumatic injuries in adults decreases failure rate of nonoperative management.
Traumatic injuries: radiological hemostatic intervention at admission.
Management options for gastric variceal hemorrhage.
限制診斷性抽血以避免醫源性貧血
Phlebotomy in the intensive care unit: strategies for blood conservation.
The increasing burden of phlebotomy in the development of anaemia and need for blood transfusion amongst trauma patients.
止血的管理和優化
Efficacy of recombinant activated Factor VII in patients with massive uncontrolled bleeding: a retrospective observational analysis.
The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage.
Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy.
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.
Alternatives to allogeneic platelet transfusion.
Desmopressin is a transfusion sparing option to reverse platelet dysfunction in patients with severe traumatic brain injury.
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients.
The exclusive use of coagulation factor concentrates enables reversal of coagulopathy and decreases transfusion rates in patients with major blunt trauma.
Antifibrinolytic drugs for acute traumatic injury.
Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study.
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate.
Topical tranexamic acid compared with anterior nasal packing for treatment of epistaxis in patients taking antiplatelet drugs: randomized controlled trial.
抗纖溶藥物
重組活化凝血因子VII（rFVIIa）
凝血因子濃縮劑
去氨加壓素
利用血液粘彈性檢測辨別外科性出血或凝血病出血
體溫管理（防止低體溫）
The effects of mild perioperative hypothermia on blood loss and transfusion requirement.
The effects of intraoperative hypothermia on surgical site infection: an analysis of 524 trauma laparotomies.
Randomized clinical trial of perioperative systemic warming in major elective abdominal surgery.
優化氧供
The influence of volume management on outcome.
Optimization of tissue oxygenation in critically ill Jehovah's Witness patients.
Severe blood loss anemia in a Jehovah's Witness treated with adjunctive hyperbaric oxygen therapy.
低壓復甦
Damage control resuscitation is associated with a reduction in resuscitation volumes and improvement in survival in 390 damage control laparotomy patients.
Hypotensive resuscitation during active hemorrhage: impact on in-hospital mortality.
Resuscitation with hydroxyethyl starch improves renal function and lactate clearance in penetrating trauma in a randomized controlled study: the FIRST trial (Fluids in Resuscitation of Severe Trauma).
Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: preliminary results of a randomized controlled trial.
Zeugen Jehovas und Schwerverletzung mit drohender Hämorrhagie. Wie komplex ist die Behandlung? [Jehovah's Witnesses and severe injury with impending hemorrhaging: how complex is the treatment?] [German, English abstract]
損傷控制策略
Preperitonal pelvic packing for hemodynamically unstable pelvic fractures: a paradigm shift.
Damage control orthopaedics: lessons learned.
Safety and efficacy of the electrothermal bipolar vessel sealer in trauma.
Damage control surgery of the critical Jehovah's Witness patient - a narrative review.
Damage control surgery.
Pelvic packing or angiography: competitive or complementary?
Safety and efficacy of damage control external fixation versus early definitive stabilization for femoral shaft fractures in the multiple-injured patient.
血液回收
Intraoperative blood salvage in penetrating abdominal trauma: a randomised, controlled trial.
Autologous blood transfusion during emergency trauma operations.
Does autotransfusion from a contaminated trauma laparotomy field increase the risk of complications?
早期貧血管理
Recombinant human erythropoietin therapy in critically ill Jehovah's Witnesses.
Recombinant human erythropoietin in severe anaemia: issues of dosing and duration.
Thalidomide for recurrent bleeding due to small-intestinal angiodysplasia.
Bloodless management of the anemic patient in the emergency department.
Improved survival of critically ill trauma patients treated with recombinant human erythropoietin.
Erythropoiesis in multiply injured patients.
Erythropoiesis-stimulating agent administration and survival after severe traumatic brain injury: a prospective study.
Zeugen Jehovas und Schwerverletzung mit drohender Hämorrhagie. Wie komplex ist die Behandlung? [Jehovah's Witnesses and severe injury with impending hemorrhaging: how complex is the treatment?] [German, English abstract]
容許等容性貧血
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.
Anemia and perioperative red blood cell transfusion: a matter of tolerance.
Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients?
Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury.
Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials.
Transfusion strategies for acute upper gastrointestinal bleeding.
臨床結果
Association of blood transfusion with increased mortality in myocardial infarction: a meta-analysis and diversity-adjusted study sequential analysis.
Allogenic blood transfusion in the first 24 hours after trauma is associated with increased systemic inflammatory response syndrome (SIRS) and death.
Allogeneic blood transfusion increases the risk of postoperative bacterial infection: a meta-analysis.
Improved outcomes and reduced costs associated with a health-system-wide patient blood management program: a retrospective observational study in four major adult tertiary-care hospitals.
Anemia and perioperative red blood cell transfusion: a matter of tolerance.
Red blood cell transfusions worsen the outcomes even in critically ill patients undergoing a restrictive transfusion strategy.
The risk of death for Jehovah's Witnesses after major trauma.
Anemia and blood transfusion in critically ill patients.
經濟效益
Impact of a patient blood management monitoring and feedback programme on allogeneic blood transfusions and related costs.
術前計劃和優化病人情況
Preparing a Jehovah's Witness for major elective surgery.
Preoperative evaluation of the adult patient undergoing non-cardiac surgery: guidelines from the European Society of Anaesthesiology.
Avoiding blood transfusion in surgical patients (including Jehovah's Witnesses).
Patient blood management is key before elective surgery.
Bloodless medicine: clinical care without allogeneic blood transfusion.
Blood transfusion and orthognathic surgery--a thing of the past?
The effect of preoperative recombinant erythropoietin on postoperative hematocrit level after orthognathic surgery.
採用多手段、多學科和個體化的方法
No increased bleeding risk for oral surgery in patients with severe congenital bleeding disorders due to intense perioperative management.
Case report: The management of advanced oral cancer in a Jehovah's Witness using the Ultracision Harmonic Scalpel.
Blood transfusion and orthognathic surgery--a thing of the past?
The use of erythropoietin in a patient having major oral and maxillofacial surgery and refusing blood transfusion.
Multimodal strategy for reduction of homologous transfusions in cranio-maxillofacial surgery.
Treatment of individuals who cannot receive blood products for religious or other reasons.
抗凝管理和逆轉
Risk of bleeding after dentoalveolar surgery in patients taking anticoagulants.
Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents.
Emergency reversal of warfarin anticoagulation.
Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers.
Reversal of clopidogrel-induced bleeding with rFVIIa in healthy subjects: a randomized, placebo-controlled, double-blind, exploratory study.
血管造影栓塞術或血流阻斷
Transarterial embolization of the external carotid artery in the treatment of life-threatening haemorrhage following blunt maxillofacial trauma.
Transarterial embolization in the management of life-threatening hemorrhage after maxillofacial trauma: a case report and review of literature.
Endovascular preoperative embolization for temporomandibular joint replacement surgery.
止血的管理和優化
The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial.
The effect of nasal application of cocaine/adrenaline on blood loss in Le Fort I osteotomies.
Effect of tranexamic acid irrigation on perioperative blood loss during orthognathic surgery: a double-blind, randomized controlled clinical trial.
Clinical applications of fibrin sealants.
Surgical removal of intra- and extraoral cavernous lymphangiomas using intraoperative-assisted intralesional fibrin glue injections.
Hemostasis of oral surgery wounds with the HemCon Dental Dressing.
The efficacy and safety of tranexamic acid in cranio-maxillofacial and plastic surgery.
Prevention of bleeding in orthognathic surgery--a systematic review and meta-analysis of randomized controlled trials.
Evaluation of the efficacy of tranexamic acid on blood loss in orthognathic surgery. A prospective, randomized clinical study.
Tranexamic acid is associated with improved operative field in orthognathic surgery.
Effectiveness of intravenous haemocoagulase on haemorrhage control in bi-maxillary orthognathic surgery-a prospective, randomised, controlled, double-blind study.
The role of antifibrinolytics in reducing blood loss during craniofacial or orthognathic surgical procedures: a meta-analysis.
Aprotinin reduces blood loss and the need for transfusion in orthognathic surgery.
Topical hemostatic agents: what the oral and maxillofacial surgeon needs to know.
Evaluation of hemorrhage depressors on blood loss during orthognathic surgery: a retrospective study.
抗纖溶藥物
去氨加壓素
其他製劑
局部止血藥
術中自體血液管理
Effects of standardized acute normovolemic hemodilution on intraoperative allogeneic blood transfusion in patients undergoing major maxillofacial surgery.
Intraoperative red cell salvage in head and neck surgery.
Acute perioperative normovolaemic haemodilution in major maxillofacial surgery.
血液回收
急性等容血液稀釋
麻醉和血液保護技術
Orthognathic surgery with or without induced hypotension.
Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study.
Effects of hypotensive anesthesia on reducing intraoperative blood loss, duration of operation, and quality of surgical field during orthognathic surgery: a systematic review and meta-analysis of randomized controlled trials.
Hypotensive anaesthesia and blood loss in orthognathic surgery: a clinical study.
Induced hypotensive anesthesia for adolescent orthognathic surgery patients.
Anesthetic considerations for orthognathic surgery with evaluation of difficult intubation and technique for hypotensive anesthesia.
High Le Fort I and bilateral split sagittal osteotomy in Crouzon syndrome.
Comparative evaluation of hypotensive and normotensive anesthesia on Lefort I osteotomies: a randomized, double-blind, prospective clinical study.
控制性降壓
術後貧血管理
Recombinant human erythropoietin in severe anaemia: issues of dosing and duration.
Intravenous ferric carboxymaltose versus standard care in the management of postoperative anaemia: a prospective, open-label, randomised controlled trial.
優化病人對貧血的耐受性
Anemia and perioperative red blood cell transfusion: a matter of tolerance.
Recombinant human erythropoietin in the treatment of head and neck tumour anaemia.
Effect of transfusion guidelines on postoperative transfusion in children undergoing craniofacial reconstruction surgery.
臨床結果
Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis.
經濟效益
Effects of standardized acute normovolemic hemodilution on intraoperative allogeneic blood transfusion in patients undergoing major maxillofacial surgery.
Patient blood management is associated with a substantial reduction of red blood cell utilization and safe for patient's outcome: a prospective, multicenter cohort study with a noninferiority design.
Acute perioperative normovolaemic haemodilution in major maxillofacial surgery.
Impact of bleeding-related complications and/or blood product transfusions on hospital costs in inpatient surgical patients.
術前病人評估和輸血風險評估
Perioperative analgesia and the effects of dietary supplements.
Herbal medicines and perioperative care.
Perioperative use of selective serotonin reuptake inhibitors and risks for adverse outcomes of surgery.
Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study.
Identifying, monitoring and reducing preventable major bleeds in the hospital setting.
Guidelines on the assessment of bleeding risk prior to surgery or invasive procedures. British Committee for Standards in Haematology.
Clinical herbal interactions with conventional drugs: from molecules to maladies.
Transfusion and coagulation management in liver transplantation.
Preoperative assessment of coagulation disorders.
Preparing a Jehovah's Witness for major elective surgery.
Aspirin in patients undergoing noncardiac surgery.
Antiplatelet drugs: a review of their pharmacology and management in the perioperative period.
Prediction of transfusion requirements in surgical patients: a review.
In the clinic. Preoperative evaluation.
Pre-operative haematological assessment in patients scheduled for major surgery.
Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study.
Preoperative assessment of the older patient: a narrative review.
The beneficial effects of minimizing blood loss in pancreatoduodenectomy.
Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery.
術前計劃和優化病人情況
Short-term preoperative diet decreases bleeding after partial hepatectomy: results from a multi-institutional randomized controlled trial.
Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines.
Optimizing postoperative outcomes with efficient preoperative assessment and management.
Merits of exercise therapy before and after major surgery.
Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in patients having combined coronary artery bypass grafting and valve surgery.
Romiplostim in the management of the thrombocytopenic surgical patient.
Bloodless medicine: what to do when you can't transfuse.
Preparation of the patient for surgery.
Recommendations from the international consensus conference on anemia management in surgical patients (ICCAMS).
Essential role of patient blood management in a pandemic: a call for action.
採用多手段、多學科和個體化的方法
Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis.
Liver transplantation in a Jehovah's Witness with ankylosing spondylitis.
Perioperative management of four anaemic female Jehovah's Witnesses undergoing urgent complex cardiac surgery.
Preparing a Jehovah's Witness for major elective surgery.
Liver transplantation in Jehovah's Witnesses: 13 consecutive cases at a single institution.
Pancreatic resections in patients who refuse blood transfusions. The application of a perioperative protocol for a true bloodless surgery.
Patient blood management: a patient-orientated approach to blood replacement with the goal of reducing anemia, blood loss and the need for blood transfusion in elective surgery.
Bloodless medicine: clinical care without allogeneic blood transfusion.
Bloodless surgery in geriatric surgery.
Perioperative management of patients for whom transfusion is not an option.
Anesthesia management of a Jehovah's Witness patient with pheochromocytoma undergoing off pump coronary artery bypass graft surgery—a case report.
Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle.
Blood conservation strategies in Jehovah's Witness patients undergoing complex aortic surgery: a report of three cases.
Aortic arch replacement and elephant trunk procedure: an interdisciplinary approach to surgical reconstruction, perfusion strategies and blood management.
Multidisciplinary management of a Jehovah's Witness patient for the removal of a renal cell carcinoma extending into the right atrium.
Update on blood conservation for cardiac surgery.
Anesthetic management for ascending aorta replacement in a patient who refused autologous transfusion for religious reasons.
Obiettivi di un programma di chirurgia senza sangue. Studio comparativo (chirurgia maggiore vs chirurgia minore-media) su 51 pazienti testimoni di Geova. [Objectives of a bloodless surgery program. A comparative study (major surgery vs. minor-medium surgery) in 51 Jehovah's Witnesses patients.] [Italian, English abstract]
Thoraco-abdominal aneurysm repair in a Jehovah's Witness: maximising blood conservation.
Programmatic blood conservation in cardiac surgery.
Allogeneic blood transfusion reduction by risk-based protocol in total joint arthroplasty.
Bloodless medicine: what to do when you can't transfuse.
Strategies to minimize intraoperative blood loss during major surgery.
Patient blood management in Europe.
2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines.
The pillars of patient blood management: key to successful implementation.
Blood-management programs: a clinical and administrative model with program implementation strategies.
A standardized multidisciplinary approach reduces the use of allogeneic blood products in patients undergoing cardiac surgery.
The perfusionist's role in a collaborative multidisciplinary approach to blood transfusion reduction in cardiac surgery.
Hypotensive anesthesia combined with tranexamic acid reduces perioperative blood loss in simultaneous bilateral total hip arthroplasty: a retrospective cohort study.
術前貧血管理和紅細胞量的優化
The role of intravenous iron in anemia management and transfusion avoidance.
The safety of intravenous iron preparations: systematic review and meta-analysis.
Impact of preoperative erythropoietin on allogeneic blood transfusions in surgical patients: results from a systematic review and meta-analysis.
Liver transplantation in Jehovah's Witnesses: 13 consecutive cases at a single institution.
The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines.
Treatment through a preoperative anemia clinic is associated with a reduction in perioperative red blood cell transfusion in patients undergoing orthopedic and gynecologic surgery.
Efficacy and safety of erythropoietin and intravenous iron in perioperative blood management: a systematic review.
International consensus statement on the peri-operative management of anaemia and iron deficiency.
'Fit to fly': overcoming barriers to preoperative haemoglobin optimization in surgical patients.
Effects of intravenous iron combined with low-dose recombinant human erythropoietin on transfusion requirements in iron-deficient patients undergoing bilateral total knee replacement arthroplasty.
Recommendations from the international consensus conference on anemia management in surgical patients (ICCAMS).
Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials.
Effect of single recombinant human erythropoietin injection on transfusion requirements in preoperatively anemic patients undergoing valvular heart surgery.
血小板減少症的管理
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia.
Romiplostim treatment allows for platelet transfusion-free liver transplantation in pediatric thrombocytopenic patient with primary sclerosing cholangitis.
Preoperative use of romiplostim in thrombocytopenic patients with chronic hepatitis C and liver cirrhosis.
Avatrombopag before procedures reduces need for platelet transfusion in patients with chronic liver disease and thrombocytopenia.
抗凝管理和逆轉
Emergency reversal of anticoagulation: from theory to real use of prothrombin complex concentrates. A retrospective Italian experience.
Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Pharmacological prophylaxis of bleeding in surgical patients treated with aspirin.
Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.
How I treat warfarin-associated coagulopathy in patients with intracerebral hemorrhage.
Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study.
Reversing the effects of antiplatelet agents in the setting of intracranial hemorrhage: a look at the literature.
Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents.
Emergency reversal of warfarin anticoagulation.
Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers.
Recent advances in the development of specific antidotes for target-specific oral anticoagulants.
Idarucizumab for dabigatran reversal - full cohort analysis.
Reversal of clopidogrel-induced bleeding with rFVIIa in healthy subjects: a randomized, placebo-controlled, double-blind, exploratory study.
Oral anticoagulation in surgical procedures: risks and recommendations.
Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding.
止血的管理和優化
Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa?
The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage.
Prophylactic use of factor IX concentrate in a Jehovah's Witness patient.
Bloodless orthotopic heart transplantation in a Jehovah's Witness.
Alternatives to allogeneic platelet transfusion.
Tranexamic acid in patients undergoing noncardiac surgery.
Fibrinogen replacement therapy: a critical review of the literature.
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study.
Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry.
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin.
Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery.
Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study.
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss.
Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology.
Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy.
Recombinant factor VIIa as last-resort treatment of desperate haemorrhage.
Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial.
Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate.
Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate.
Association of intravenous tranexamic acid with thromboembolic events and mortality: a systematic review, meta-analysis, and meta-regression.
Oral is as effective as intravenous tranexamic acid at reducing blood loss in thoracolumbar spinal fusions: a prospective randomized trial.
抗纖溶藥物
重組活化凝血因子VII（rFVIIa）
凝血因子濃縮劑
去氨加壓素
利用血液粘彈性檢測辨別外科性出血或凝血病出血
體溫管理（防止低體溫）
Influence of body core temperature on blood loss and transfusion requirements during off-pump coronary artery bypass grafting: A comparison of 3 warming systems.
Effectiveness of strategies for the management and/or prevention of hypothermia within the adult perioperative environment.
The effects of mild perioperative hypothermia on blood loss and transfusion requirement.
Mild hypothermia increases blood loss and transfusion requirements during total hip arthroplasty.
A systematic review of intraoperative warming to prevent postoperative complications.
Intraoperative core temperature patterns, transfusion requirement, and hospital duration in patients warmed with forced air.
Aggressive warming reduces blood loss during hip arthroplasty.
Randomized clinical trial of perioperative systemic warming in major elective abdominal surgery.
謹慎進行液體和容量管理
Perioperative fluid management strategies in major surgery: a stratified meta-analysis.
How good patient blood management leads to excellent outcomes in Jehovah's Witness patients undergoing cardiac surgery.
Restrictive strategy of intraoperative fluid maintenance during optimization of oxygen delivery decreases major complications after high-risk surgery.
Choice of fluid in acute illness: what should be given? An international consensus.
Strategies to reduce the use of blood products: a European perspective.
Impact of goal-directed perioperative fluid management in high-risk surgical procedures: a literature review.
Safety of modern starches used during surgery.
Management of intraoperative fluid balance and blood conservation techniques in adult cardiac surgery.
術中自體血液管理
Safety of intraoperative blood salvage during liver transplantation in patients with hepatocellular carcinoma: A systematic review and meta-analysis.
Cell salvage in obstetrics.
Does autologous blood transfusion during liver transplantation for hepatocellular carcinoma increase risk of recurrence?
Cell salvage as part of a blood conservation strategy in anaesthesia.
Phase II comparison study of intraoperative autotransfusion for major oncologic procedures.
Autologous blood transfusion during emergency trauma operations.
Cell salvage for minimising perioperative allogeneic blood transfusion.
Cerebral effect of acute normovolemic hemodilution during brain tumor resection.
Very low rate of patient-related adverse events associated with the use of intraoperative cell salvage.
Intra-operative cell salvage: a fresh look at the indications and contraindications.
Role of intraoperative red cell salvage and autologus transfusion in metastatic spine surgery: a pilot study and review of literature.
Greater volume of acute normovolemic hemodilution may aid in reducing blood transfusions after cardiac surgery.
Oncologic outcomes following radical prostatectomy with intraoperative cell salvage.
The use of acute hemodilution in parturients undergoing cesarean section.
Safety of the use of blood salvage and autotransfusion during liver transplantation for hepatocellular carcinoma.
A case of thoracic esophageal cancer undergone esophagectomy after induction chemotherapy in a Jehovah's Witness.
A prospective randomized trial of acute normovolemic hemodilution compared to standard intraoperative management in patients undergoing major hepatic resection.
Acute normovolemic hemodilution and nitroglycerin-induced hypotension: comparative effects on tissue oxygenation and allogeneic blood transfusion requirement in total hip arthroplasty.
Association of Anaesthetists guidelines: cell salvage for peri-operative blood conservation 2018.
Transfusion-free strategies in liver and pancreatic surgery: a predictive model of blood conservation for transfusion avoidance in mainstream populations.
Can there be a place for intraoperative salvaged blood in spine tumor surgery?
Use of intraoperative cell-salvage for autologous blood transfusions in metastatic spine tumour surgery: a systematic review.
Metastatic efficiency of tumour cells can be impaired by intraoperative cell salvage process: truth or conjecture?
A prospective randomized study comparing two techniques of perioperative blood conservation: isovolemic hemodilution and hypervolemic hemodilution.
Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass surgery.
The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer.
Acute normovolemic hemodilution.
Acute normovolemic hemodilution, intraoperative cell salvage and PulseCO hemodynamic monitoring in a Jehovah's Witness with placenta percreta.
Intraoperative cell salvage during radical cystectomy does not affect long-term survival.
Acute normovolemic hemodilution is safe in neurosurgery.
Intraoperative cell salvage in radical prostatectomy does not appear to increase long-term biochemical recurrence, metastases, or mortality.
Impaired red blood cell deformability after transfusion of stored allogeneic blood but not autologous salvaged blood in cardiac surgery patients.
The effect of acute normovolemic hemodilution and acute hypervolemic hemodilution on coagulation and allogeneic transfusion.
Is cell salvage safe in liver resection? A pilot study.
Acute normovolemic hemodilution.
Perioperative management including dual cell salvage in a Jehovah's Witness patient undergoing major urological surgery.
Intra-operative cell salvage in South Africa: feasible, beneficial and economical.
Should intraoperative cell-salvaged blood be used in patients with suspected or known malignancy?
Blood salvage and cancer surgery: a meta-analysis of available studies.
Предоперацонная гиперволемическая гемодилюция 6% гидроксиэтил-крахмалом 130/0,4 (HES 130/0,4) как способ сокращения потребности в трансфузии донорской крови. [Preoperative hypervolemic hemodilution with 6% hydroxyethyl starch 130/0,4 (HES 130/ 0.4) solution as a way of reducing needs for donor blood transfusion.] [Russian, English abstract]
血液回收
急性等容血液稀釋
麻醉和血液保護技術
Greater peripheral blood flow but less bleeding with propofol versus sevoflurane during spine surgery: a possible physiologic model?
Controlled hypotension: a guide to drug choice.
Controlled hypotension for spinal surgery.
Magnesium sulphate as a technique of hypotensive anaesthesia.
Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study.
The safety of controlled hypotension for shoulder arthroscopy in the beach-chair position.
The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis.
Influence of controlled hypotension versus normotension on amount of blood loss during breast reduction.
A comparison of neuraxial block versus general anesthesia for elective total hip replacement: a meta-analysis.
Comparison of outcomes of using spinal versus general anesthesia in total hip arthroplasty.
Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: preliminary results of a randomized controlled trial.
Comparison of hypotensive epidural anaesthesia and spinal anaesthesia on blood loss and coagulation during and after total hip arthroplasty.
Induced hypotension with epidural/general anesthesia reduces transfusion in radical prostate surgery.
Laparoscopic and robotic partial nephrectomy with controlled hypotensive anesthesia to avoid hilar clamping: feasibility, safety and perioperative functional outcomes.
Anaesthesia for hip fracture surgery in adults.
Deliberate hypotension in orthopedic surgery reduces blood loss and transfusion requirements: a meta-analysis of randomized controlled trials.
Does neuraxial anesthesia reduce intraoperative blood loss? A meta-analysis.
Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials.
Comparative perioperative outcomes associated with neuraxial versus general anesthesia for simultaneous bilateral total knee arthroplasty.
High Le Fort I and bilateral split sagittal osteotomy in Crouzon syndrome.
控制性降壓
局部麻醉
限制診斷性抽血以避免醫源性貧血
Comparison of structured use of routine laboratory tests or near-patient assessment with clinical judgement in the management of bleeding after cardiac surgery.
Savoring every drop—vampire or mosquito?
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study.
Diagnostic blood loss from phlebotomy and hospital-acquired anemia during acute myocardial infarction.
Surgical vampires and rising health care expenditure: reducing the cost of daily phlebotomy.
Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients.
術後貧血管理
Recombinant human erythropoietin therapy in critically ill Jehovah's Witnesses.
Severe acute anemia after liver transplantation in an elderly Jehovah's Witness treated with high-dose erythropoietin and ferric carboxymaltose: a case report.
Recombinant human erythropoietin in severe anaemia: issues of dosing and duration.
Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized, double-blind, placebo-controlled trial.
The role of erythropoietin therapy in the critically ill.
Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317].
Intravenous ferric carboxymaltose versus standard care in the management of postoperative anaemia: a prospective, open-label, randomised controlled trial.
Safety of off-label erythropoiesis stimulating agents in critically ill patients: a meta-analysis.
An international consensus statement on the management of postoperative anaemia after major surgical procedures.
How do we treat life-threatening anemia in a Jehovah's Witness patient?
Recombinant human erythropoietin use in a critically ill Jehovah's Witness after cardiac surgery.
Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery.
Life-threatening postoperative blood loss in a Jehovah's Witness, treated with high-dose erythropoietin.
Transfusion-free management of gastrointestinal bleeding: the experience of a Bloodless Institute.
Efficacy of recombinant human erythropoietin in critically ill patients admitted to a long-term acute care facility: a randomized, double-blind, placebo-controlled trial.
優化病人對貧血的耐受性
The influence of volume management on outcome.
Hyperbaric oxygen reverses organ dysfunction in severe anemia.
Management of a Jehovah's Witness patient with sepsis and profuse bleeding after emergency coronary artery bypass graft surgery: rethinking the critical threshold of oxygen delivery.
Hyperoxic ventilation at the critical haematocrit.
Prophylactic hypothermia and neuromuscular blockade to limit myocardial oxygen demand in a critically anemic Jehovah's Witness after emergency surgery.
Pillar III—optimisation of anaemia tolerance.
Norepinephrine increases tolerance to acute anemia.
Transfusion-free management of gastrointestinal bleeding: the experience of a Bloodless Institute.
容許等容性貧血
Liberal or restrictive transfusion in high-risk patients after hip surgery.
Patient blood management: a patient-orientated approach to blood replacement with the goal of reducing anemia, blood loss and the need for blood transfusion in elective surgery.
Restrictive blood transfusion practices are associated with improved patient outcomes.
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.
Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis.
Transfusion strategies for patients in pediatric intensive care units.
Anemia and perioperative red blood cell transfusion: a matter of tolerance.
Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients?
Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury.
Pillar III—optimisation of anaemia tolerance.
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review.
Mortality and morbidity in non-transfusable and transfusable patients: a systematic review and meta-analysis.
大量出血的不利影響
The beneficial effects of minimizing blood loss in pancreatoduodenectomy.
輸血風險和不確定性
Blood transfusion and cancer surgery outcomes: a continued reason for concern.
Surgical outcomes and transfusion of minimal amounts of blood in the operating room.
Adverse blood transfusion outcomes: establishing causation.
Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting.
Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature.
Survival rate changes with transfusion of blood products during liver transplantation.
Emerging infectious disease agents and their potential threat to transfusion safety.
Current perspectives in transfusion-transmitted infectious diseases: emerging and re-emerging infections.
臨床結果
Peri-operative blood transfusion increases length of hospital stay and number of postoperative complications in non-cardiac surgical patients.
Association between the use of blood components and the five-year mortality after liver transplant. [Associação entre Uso de Hemocomponentes e Mortalidade em Cinco Anos após Transplante Hepático.] [English, Portuguese]
How good patient blood management leads to excellent outcomes in Jehovah's Witness patients undergoing cardiac surgery.
Methods of bloodless care, clinical outcomes, and costs for adult patients who decline allogeneic transfusions.
Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Association between intraoperative blood transfusion and mortality and morbidity in patients undergoing noncardiac surgery.
Restrictive blood transfusion practices are associated with improved patient outcomes.
Intraoperative cardiac arrests in adults undergoing noncardiac surgery: incidence, risk factors, and survival outcome.
"Bloodless" neurosurgery among Jehovah's Witnesses: a comparison with matched concurrent controls.
Review article: Risks of anemia and related management strategies: can perioperative blood management improve patient safety?
Cardiac surgery in Jehovah's Witness patients: ten-year experience.
The impact of blood conservation on outcomes in cardiac surgery: is it safe and effective?
Outcome of patients who refuse transfusion after cardiac surgery: a natural experiment with severe blood conservation.
Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery.
Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis.
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review.
Clinical efficacy of implementing a patient blood management (PBM) protocol in joint replacement surgery: a retrospective cohort study in a national referral center.
Mortality and morbidity in non-transfusable and transfusable patients: a systematic review and meta-analysis.
Blood-management programs: a clinical and administrative model with program implementation strategies.
Implementation of a comprehensive patient blood management program for hospitalized patients at a large united states medical center.
From product to patient-transfusion and patient blood management.
Safety and efficacy of methods for reducing perioperative allogeneic transfusion: a critical review of the literature.
經濟效益
Cost-effectiveness of cell salvage and alternative methods of minimising perioperative allogeneic blood transfusion: a systematic review and economic model.
Estimating the epidemiological and economic impact of implementing preoperative anaemia measures in the German healthcare system: the health economic footprint of patient blood management.
Greater than sevenfold return on investment for a comprehensive patient blood management program with equivalent or improved outcomes.
Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
Economic considerations on transfusion medicine and patient blood management.
Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery.
Blood product conservation is associated with improved outcomes and reduced costs after cardiac surgery.
From blood transfusion to patient blood management: a new paradigm for patient care and cost assessment of blood transfusion practice.
Safety, cost savings, simplicity back broader use of bloodless surgery.
Associations between preoperative anaemia and hospital costs following major abdominal surgery: cohort study.
Effects of intravenous iron combined with low-dose recombinant human erythropoietin on transfusion requirements in iron-deficient patients undergoing bilateral total knee replacement arthroplasty.
ONTraC: a 20-year history of a successfully coordinated provincewide patient blood management program: Lessons learned and goals achieved.
A prospective study investigating the cost effectiveness of intraoperative blood salvage during liver transplantation.
Effective reduction of blood product use in a community teaching hospital: when less is more.
Prospective monitoring of plasma and platelet transfusions in a large teaching hospital results in significant cost reduction.
Activity-based costs of blood transfusions in surgical patients at four hospitals.
Intra-operative cell salvage in South Africa: feasible, beneficial and economical.
Randomized trial comparing packed red cell blood transfusion with and without leukocyte depletion for gastrointestinal surgery.
Implementation of a comprehensive patient blood management program for hospitalized patients at a large united states medical center.
The volume of returned red blood cells in a large blood salvage program: where does it all go?
An economic analysis of costs associated with development of a cell salvage program.
術前病人評估和輸血風險評估
Identifying patients at risk of intraoperative and postoperative transfusion in isolated CABG: toward selective conservation strategies.
Perioperative care of a Jehovah's Witness with a leaking abdominal aortic aneurysm.
Blood loss and transfusion rates associated with transcatheter aortic valve replacement: recommendations for patients who refuse blood transfusion.
Association between bleeding events and in-hospital mortality after percutaneous coronary intervention.
Preoperative hemostasis and its association with bleeding and blood component transfusion requirements in cardiopulmonary bypass surgery.
2012 update to the Society of Thoracic Surgeons Guideline on use of antiplatelet drugs in patients having cardiac and noncardiac operations.
Relation of the HAS-BLED bleeding risk score to major bleeding, cardiovascular events, and mortality in anticoagulated patients with atrial fibrillation.
Preoperative anemia is an independent predictor of postoperative mortality and adverse cardiac events in elderly patients undergoing elective vascular operations.
Predictors of bleeding and time dependence of association of bleeding with mortality: insights from the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel--Thrombolysis in Myocardial Infarction 38 (TRITON-TIMI 38).
Cardiac surgery in Jehovah's Witness patients: ten-year experience.
A multivariable model for predicting the need for blood transfusion in patients undergoing first-time elective coronary bypass graft surgery.
Interrelationship of preoperative anemia, intraoperative anemia, and red blood cell transfusion as potentially modifiable risk factors for acute kidney injury in cardiac surgery: a historical multicentre cohort study.
The influence of baseline hemoglobin concentration on tolerance of anemia in cardiac surgery.
Transfusion Risk and Clinical Knowledge (TRACK) score and cardiac surgery in patients refusing transfusion.
Combined clopidogrel and aspirin treatment up to surgery increases the risk of postoperative myocardial infarction, blood loss and reoperation for bleeding in patients undergoing coronary artery bypass grafting.
Predictors of transfusion requirements for cardiac surgical procedures at a blood conservation center.
Identification des facteurs prédictifs de transfusion sanguine homologue en chirurgie cardiaque à partir d'une étude observationnelle. [Identification of risk factors for allogenic transfusion in cardiac surgery from an observational study.] [French]
Aortic valve replacement through a minimally invasive approach: preoperative planning, surgical technique, and outcome.
Major bleeding, transfusions, and anemia: the deadly triad of cardiac surgery.
Predicting transfusions in cardiac surgery: the easier, the better: the Transfusion Risk and Clinical Knowledge score.
Impact of preoperative anemia on outcome in adult cardiac surgery: a propensity-matched analysis.
Preparation of the patient for surgery.
Risk factors for red cell transfusion in adults undergoing coronary artery bypass surgery: a systematic review.
Factors predicting loss and gain of red cell volume in cardiac surgery patients.
The effect of pre-operative aspirin on bleeding, transfusion, myocardial infarction, and mortality in coronary artery bypass surgery: a systematic review of randomized and observational studies.
A surgeon's guide to herbal supplements.
Risk factors for red blood cell transfusion after coronary artery bypass graft surgery.
Blood conservation strategies can be applied safely to high-risk complex aortic surgery.
Management of blood transfusion in aortic valve surgery: impact of a blood conservation strategy.
術前計劃和優化病人情況
Hybrid approach to pulmonary valve replacement with melody prosthesis following pulmonary banding.
Changes in haemoglobin levels during hospital course and long-term outcome after acute myocardial infarction.
Preoperative assessment and management to prevent complications during high-risk vascular surgery.
Preparing a Jehovah's Witness for major elective surgery.
Effect on outcomes and exercise performance of anemia in patients with aortic stenosis who underwent transcatheter aortic valve replacement.
The operating surgeon is an independent predictor of chest tube drainage following cardiac surgery.
Preoperative hemostasis and its association with bleeding and blood component transfusion requirements in cardiopulmonary bypass surgery.
Avoiding blood transfusion in surgical patients (including Jehovah's Witnesses).
Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in patients having combined coronary artery bypass grafting and valve surgery.
The theory and practice of bloodless surgery.
Strategies and outcomes of cardiac surgery in Jehovah's Witnesses.
Prevalence, factors associated with, and prognostic effects of preoperative anemia on short- and long-term mortality in patients undergoing transcatheter aortic valve implantation.
The association of perioperative transfusion with 30-day morbidity and mortality in patients undergoing major vascular surgery.
Aortic valve replacement in a Jehovah's Witness: a case of multi-disciplinary clinical management for bloodless surgery.
An updated bleeding model to predict the risk of post-procedure bleeding among patients undergoing percutaneous coronary intervention: a report using an expanded bleeding definition from the National Cardiovascular Data Registry CathPCI Registry.
Heart transplant in Jehovah's Witness patients: a case-control study.
Preparation of the patient for surgery.
Optimizing transfusion in vascular surgery: is bloodless surgery an option?
Preoperative hematocrit as a predictor of perioperative morbidities following nonemergent coronary artery bypass surgery.
Cardiovascular surgery in Jehovah's Witness patients: the role of preoperative optimization.
STS/SCA/AmSECT/SABM update to the clinical practice guidelines on patient blood management.
Impact of haemoglobin concentration on cardiovascular outcome after vascular surgery: a retrospective observational cohort study.
Preoperative optimization of the vascular surgery patient.
採用多手段、多學科和個體化的方法
Blood conservation strategies in cardiac surgery: more is better.
Blood loss and transfusion rates associated with transcatheter aortic valve replacement: recommendations for patients who refuse blood transfusion.
Blood transfusion reduction in cardiac surgery: multidisciplinary approach at a community hospital.
Perioperative management of four anaemic female Jehovah's Witnesses undergoing urgent complex cardiac surgery.
Bilateral sequential lung transplantation in Jehovah's Witnesses.
Aortic valve replacement in a dialysis-dependent Jehovah's Witness: successful use of a minicircuit, microplegia, and multimodality blood conservation technique.
Blood conservation strategies reduce the need for transfusions in ascending and aortic arch surgery.
Conservation of blood during cardiovascular surgery.
Bloodless orthotopic heart transplantation in a Jehovah's Witness.
Repair of type A dissection in a Jehovah's Witness with prior cardiac operation.
Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass.
Double-valve surgery in Shprintzen-Goldberg syndrome.
Repeat cardiac surgery in a Jehovah's Witness patient with thrombocytopenia.
Should Jehovah's Witness patients be listed for heart transplantation?
Cardiopulmonary bypass in Jehovah's Witnesses.
Successful ascending aorta and hemiarch replacement and aortic valve resuspension via redo median sternotomy using hypothermic circulatory arrest in a practicing Jehovah's Witnesses patient.
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.
Jehovah's Witnesses requiring complex urgent cardiothoracic surgery.
Successful allograft root re-replacement for prosthetic valve endocarditis with improvement of renal function in a Jehovah's Witness patient.
Anesthesia management of a Jehovah's Witness patient with pheochromocytoma undergoing off pump coronary artery bypass graft surgery—a case report.
Treatment of anemia in patients with heart disease: a systematic review.
Total aortic arch replacement for the treatment of Kommerell's diverticulum in a Jehovah's Witness.
An evolution in blood management: past, present, and future.
Blood conservation—a team sport.
Blood conservation strategies in Jehovah's Witness patients undergoing complex aortic surgery: a report of three cases.
Aortic arch replacement and elephant trunk procedure: an interdisciplinary approach to surgical reconstruction, perfusion strategies and blood management.
Multidisciplinary management of a Jehovah's Witness patient for the removal of a renal cell carcinoma extending into the right atrium.
Update on blood conservation for cardiac surgery.
Anesthetic management for ascending aorta replacement in a patient who refused autologous transfusion for religious reasons.
Successful surgical repair of acute type A aortic dissection without the use of blood products.
Aortic valve replacement in a Jehovah's Witness: a case of multi-disciplinary clinical management for bloodless surgery.
Bloodless third complex heart operation in a Jehovah's Witness patient with extremely low preoperative haemoglobin level.
Aortic valve replacement and repair of left ventricular pseudoaneurysm in a Jehovah's Witness.
Thoraco-abdominal aneurysm repair in a Jehovah's Witness: maximising blood conservation.
Programmatic blood conservation in cardiac surgery.
Multi-modality blood conservation strategy in open-heart surgery: an audit.
Successful use of ECMO in a Jehovah's Witness after complicated re-heart transplant.
Therapeutic options to minimize allogeneic blood transfusions and their adverse effects in cardiac surgery: a systematic review. [Opções terapêuticas para minimizar transfusões de sangue alogênico e seus efeitos adversos em cirurgia cardíaca: revisão sistemática.] [English, Portuguese]
Bloodless aortic valve and ascending aorta replacement surgery requiring circulatory arrest: two case studies.
2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines.
Effects of a targeted blood management programme on allogeneic blood transfusion in abdominal aortic aneurysm surgery.
A structured blood conservation programme reduces transfusions and costs in cardiac surgery.
Effects of a multimodality blood conservation schema toward improvement of intraoperative hemoglobin levels and off-pump transfusions in coronary artery bypass graft surgery.
A standardized multidisciplinary approach reduces the use of allogeneic blood products in patients undergoing cardiac surgery.
Ten-year patterns in blood product utilization during cardiothoracic surgery with cardiopulmonary bypass in a tertiary hospital.
Coronary artery bypass grafting in a dialysis-dependent Jehovah's Witness.
Implementation of a comprehensive blood conservation program can reduce blood use in a community cardiac surgery program.
Blood conservation strategies can be applied safely to high-risk complex aortic surgery.
Management of blood transfusion in aortic valve surgery: impact of a blood conservation strategy.
Rupture of chronic type B aortic dissection in a Jehovah's Witness: successful surgical repair without blood transfusion.
The perfusionist's role in a collaborative multidisciplinary approach to blood transfusion reduction in cardiac surgery.
術前貧血管理和紅細胞量的優化
Ferric carboxymaltose in patients with heart failure and iron deficiency.
Successful repair of a giant abdominal aortoiliac aneurysm in a Jehovah's Witness.
Blood loss and transfusion rates associated with transcatheter aortic valve replacement: recommendations for patients who refuse blood transfusion.
Impact of preoperative erythropoietin on allogeneic blood transfusions in surgical patients: results from a systematic review and meta-analysis.
Epoetin dosing for blood conservation in Jehovah's Witness patients undergoing cardiac surgery—a systematic review.
Effects of preoperative intravenous erythropoietin plus iron on outcome in anemic patients after cardiac valve replacement.
Intravenous ferric carboxymaltose in iron-deficient chronic heart failure patients with and without anaemia: a subanalysis of the FAIR-HF trial.
Current status of pharmacologic therapies in patient blood management.
Intraoperative anemia and single red blood cell transfusion during cardiac surgery: an assessment of postoperative outcome including patients refusing blood transfusion.
The influence of baseline hemoglobin concentration on tolerance of anemia in cardiac surgery.
Randomised open-label trial comparing intravenous iron and an erythropoiesis-stimulating agent versus oral iron to treat preoperative anaemia in cardiac surgery (INITIATE trial).
Efficacy and safety of erythropoietin and intravenous iron in perioperative blood management: a systematic review.
The least of 3 evils: exposure to red blood cell transfusion, anemia, or both?
Jehovah's Witnesses and cardiac surgery: a single institution's experience.
Determining optimal treatment to correct preoperative anemia and reduce perioperative allogeneic blood transfusions in cardiac surgery: a retrospective cohort study.
Randomized, double-blind, placebo-controlled trial of effects of enteral iron supplementation on anemia and risk of infection during surgical critical illness.
Efficacy of quadruple treatment on different types of pre-operative anaemia: secondary analysis of a randomised controlled trial.
Preoperative erythropoietin and blood conservation management for thoracoabdominal aneurysm repair in a Jehovah's Witness.
Intravenous iron in heart failure: beyond targeting anemia.
Cardiovascular surgery in Jehovah's Witness patients: the role of preoperative optimization.
Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency.
Preoperative very short-term, high-dose erythropoietin administration diminishes blood transfusion rate in off-pump coronary artery bypass: a randomized blind controlled study.
A single dose of erythropoietin reduces perioperative transfusions in cardiac surgery: results of a prospective single-blind randomized controlled trial.
Blood conservation strategies can be applied safely to high-risk complex aortic surgery.
Effect of single recombinant human erythropoietin injection on transfusion requirements in preoperatively anemic patients undergoing valvular heart surgery.
抗凝管理和逆轉
Prothrombin complex concentrates versus fresh frozen plasma for warfarin reversal. A systematic review and meta-analysis.
Pharmacological prophylaxis of bleeding in surgical patients treated with aspirin.
Reversal of warfarin: case-based practice recommendations.
Stopping antiplatelet medication before coronary artery bypass graft surgery: is there an optimal timing to minimize bleeding?
Is a fully heparin-bonded cardiopulmonary bypass circuit superior to a standard cardiopulmonary bypass circuit?
Heparin-bonded circuits versus nonheparin-bonded circuits: an evaluation of their effect on clinical outcomes.
Heparin-coated extracorporeal circulation in combination with low dose systemic heparinization reduces early postoperative blood loss in cardiac surgery.
Idarucizumab for dabigatran reversal.
Idarucizumab for dabigatran reversal - full cohort analysis.
Platelet mapping and desmopressin reversal of platelet inhibition during emergency carotid endarterectomy.
Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study.
Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting: a multicenter randomized trial.
Andexanet alfa for the reversal of Factor Xa inhibitor activity.
Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding.
Heparinized cardiopulmonary bypass circuits and low systemic anticoagulation: an analysis of nearly 6000 patients undergoing coronary artery bypass grafting.
限制非診斷性失血
Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal.
Bleeding avoidance strategies. Consensus and controversy.
Influence of arterial access site selection on outcomes in primary percutaneous coronary intervention: are the results of randomized trials achievable in clinical practice?
血管造影栓塞術或血流阻斷
Resection of intralobar pulmonary sequestration after coil embolization of aberrant arteries: report of a case.
A multidisciplinary approach to carotid paragangliomas.
Impact of preoperative embolization on outcomes of carotid body tumor resections.
Intraoperative embolization with poloxamer 407 during surgical resection of a carotid body tumor.
外科血液保護技術
Reduced re-exploration and blood product transfusion after the introduction of the Papworth haemostasis checklist.
Repair of an ascending aortic aneurysm using reduction aortoplasty in a Jehovah's Witness.
A randomised controlled trial of the use of a tourniquet to reduce blood loss during transtibial amputation for peripheral arterial disease.
Conservation of blood during cardiovascular surgery.
Planned versus unplanned reexplorations for bleeding: a comparison of morbidity and mortality.
The operating surgeon is an independent predictor of chest tube drainage following cardiac surgery.
Reoperation in a Jehovah's Witness 22 years after aortic allograft reconstruction of the right ventricular outflow tract.
Repair of a large main pulmonary artery aneurysm in a 71-year-old Jehovah's Witness patient.
Successful allograft root re-replacement for prosthetic valve endocarditis with improvement of renal function in a Jehovah's Witness patient.
Staged repair for a chronic dissecting thoracic aortic aneurysm with no transfusion in a Jehovah's Witness patient.
Reexploration for bleeding after coronary artery bypass surgery: risk factors, outcomes, and the effect of time delay.
Process improvement in cardiac surgery: development and implementation of a reoperation for bleeding checklist.
Successful surgical treatment of a ruptured abdominal aortic aneurysm without homologous blood transfusion in a Jehovah's Witness: report of a case.
Unusual modification of the cabrol shunt for control of hemorrhage in acute type A aortic dissection.
Bloodless surgery of acute type A aortic dissection in a Jehovah's Witness patient.
Using the Boazul cuff to reduce blood loss in varicose vein surgery.
Hybrid operation for combined aortic arch aneurysm and aortic root dilation in a Jehovah's Witness patient.
Novel wrapping technique with insertion of fat tissue for hemostasis in aortic surgery.
CASE 12-2016 Ascending aorta dissection in a Jehovah's Witness patient on warfarin.
Controlled hypotension and minimal inflation pressure: a new approach for pneumatic tourniquet application in upper limb surgery.
Staged hybrid approach for an acute-on-chronic aortic dissection with rupture in a Jehovah's Witness patient: case report.
Use of a pneumatic tourniquet improves outcome following trans-tibial amputation.
Minimally invasive hybrid treatment of acute type I aortic dissection: a single-stage technique without circulatory arrest.
微創方法
Hybrid approach to pulmonary valve replacement with melody prosthesis following pulmonary banding.
Off-pump myocardial revascularizaton in a Jehovah's Witness patient with pheochromocytoma.
Blood loss and transfusion rates associated with transcatheter aortic valve replacement: recommendations for patients who refuse blood transfusion.
Endovascular treatment of multiple anomalous splenic artery aneurysms in a Jehovah's Witness.
Transcatheter aortic valve implantation in Jehovah's Witness patients with symptomatic severe aortic valve stenosis.
Percutaneous embolization of lung sequestration using a novel occluding device.
Outcomes of coronary artery bypass graft surgery versus drug-eluting stents in older adults.
Resection of left ventricular rhabdomyosarcoma.
Bleeding complications after surgical aortic valve replacement compared with transcatheter aortic valve replacement: insights from the PARTNER I Trial (Placement of Aortic Transcatheter Valve).
Beating heart minimally invasive mitral valve surgery in patients with patent coronary bypass grafts. [English, French abstract]
Minimally invasive approach provides at least equivalent results for surgical correction of mitral regurgitation: a propensity-matched comparison.
Heart-failing Jehovah's Witness patient successfully treated by minimally invasive LVAD implantation without any blood transfusions.
Thoracoscopic treatment of pulmonary sequestration.
Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.
Endovascular repair of ascending aortic dissection: a novel treatment option for patients judged unfit for direct surgical repair.
Complete replacement of open repair for ruptured abdominal aortic aneurysms by endovascular aneurysm repair: a two-center 14-year experience.
One thousand minimally invasive mitral valve operations: early outcomes, late outcomes, and echocardiographic follow-up.
Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011.
Minimally invasive mitral valve surgery: a systematic review and meta-analysis.
Minimally invasive mitral valve surgery through right thoracotomy in patients with patent coronary artery bypass grafts.
Hybrid minimally invasive extraction of atrial clot avoids redo sternotomy in Jehovah's Witness.
Aortic valve replacement through a minimally invasive approach: preoperative planning, surgical technique, and outcome.
Endovascular repair of aortic arch false aneurysm with branched endograft.
Endovascular treatment of a superior mesenteric artery embolism in a high-risk Jehovah's Witness.
Impact of timing and surgical approach on outcomes after mitral valve regurgitation operations.
Mitral valve surgery: right lateral minithoracotomy or sternotomy? A systematic review and meta-analysis.
Minimal access aortic valve replacement using a minimal extracorporeal circulatory system.
止血的管理和優化
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis. [L'application topique de médicaments anti-fibrinolytiques pour la chirurgie cardiaque avec circulation extra-corporelle : analyse méthodique et méta-analyse.] [English, French abstract]
A comprehensive review of topical hemostatic agents: efficacy and recommendations for use.
Reduced use of allogeneic platelets through high-yield perioperative autologous plateletpheresis and reinfusion.
An audit of red cell and blood product use after the institution of thromboelastometry in a cardiac intensive care unit.
Use of prothrombin complex concentrate for excessive bleeding after cardiac surgery.
Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa?
A review of topical hemostatic agents for use in cardiac surgery.
Use of recombinant activated factor VII for refractory after lung transplant bleeding as an effective strategy to restrict blood transfusion and associated complications.
Reducing blood transfusion in aortic surgery: a novel approach.
Prophylactic use of factor IX concentrate in a Jehovah's Witness patient.
Safety and efficacy of prothrombin complex concentrate as first-line treatment in bleeding after cardiac surgery.
Bloodless orthotopic heart transplantation in a Jehovah's Witness.
State of the art - how I manage coagulopathy in cardiac surgery patients.
Can topical application of tranexamic acid reduce blood loss in thoracic surgery? A prospective randomised double blind investigation.
Recombinant activated factor VII in cardiac surgery: experience from the Australian and New Zealand Haemostasis Registry.
Repeat cardiac surgery in a Jehovah's Witness patient with thrombocytopenia.
Can local application of tranexamic acid reduce post-coronary bypass surgery blood loss? A randomized controlled trial.
Off-label use of recombinant activated factor VII for cardiac surgical bleeding.
Armentarium of topical hemostatic products in cardiovascular surgery: an update.
Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery.
Intraoperative use of recombinant activated factor VII during complex aortic surgery.
Off-label use of recombinant human factor VIIa.
Current status of pharmacologic therapies in patient blood management.
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study.
Management of hemorrhage in cardiothoracic surgery.
The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: a randomized, double-blind, placebo-controlled, noninferiority trial.
Off-label use of recombinant activated factor VII in intractable haemorrhage after cardiovascular surgery: an observational study of practices in 23 French cardiac centres (2005-7).
Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry.
Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin.
Comparison of 4-factor prothrombin complex concentrate with frozen plasma for management of hemorrhage during and after cardiac surgery: a randomized pilot trial.
Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery.
The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery.
Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study.
Role of recombinant factor VIIa in the treatment of intractable bleeding in vascular surgery.
Use of activated recombinant factor VII in severe bleeding—evidence for efficacy and safety in trauma, postpartum hemorrhage, cardiac surgery, and gastrointestinal bleeding.
Recombinant activated factor VII for postoperative hemorrhage following repair of acute type A aortic dissection.
A novel reverse thermosensitive polymer to achieve temporary atraumatic vessel occlusion in infra-popliteal bypasses.
Comparative evaluation of the effects of tranexamic acid and low-dose aprotinin on post-valvular heart surgery bleeding and allogenic transfusion.
Recombinant factor VIIa treatment of severe bleeding in cardiac surgery patients: a retrospective analysis of dosing, efficacy, and safety outcomes.
Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011.
A randomized trial of tranexamic acid in combination with cell salvage plus a meta-analysis of randomized trials evaluating tranexamic acid in off-pump coronary artery bypass grafting.
Tranexamic acid in patients undergoing coronary-artery surgery.
Aprotinin for patients exposed to clopidogrel before off-pump coronary bypass.
Recombinant activated factor VII significantly reduces transfusion requirements in cardiothoracic surgery.
Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: results from a randomized, placebo-controlled trial.
Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial.
Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery.
Fibrinogen supplementation after cardiac surgery: insights from the zero-plasma trial (ZEPLAST).
Platelet mapping and desmopressin reversal of platelet inhibition during emergency carotid endarterectomy.
Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate.
Prothrombin complex concentrate in cardiac surgery: a systematic review and meta-analysis.
Control of troublesome bleeding during repair of acute type A dissection with use of modified rapid deployment hemostat (MRDH).
Topical haemostatic agents.
Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting: a multicenter randomized trial.
Effect of high- vs low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery: The OPTIMAL randomized clinical trial.
Coagulopathy after cardiopulmonary bypass in Jehovah's Witness patients: management of two cases using fractionated components and factor VIIa.
Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products.
Hemostatic management of severe thrombocytopenia in a patient undergoing pulmonic valve replacement.
Treatment of excessive bleeding in Jehovah's Witness patients after cardiac surgery with recombinant factor VIIa (Novoseven®).
Desmopressin for reducing postoperative blood loss and transfusion requirements following cardiac surgery in adults.
Tranexamic acid reduces blood loss after off-pump coronary surgery: a prospective, randomized, double-blind, placebo-controlled study.
Effects of aprotinin on short-term and long-term outcomes after coronary artery bypass grafting surgery.
Recombinant activated factor VII in cardiac surgery: a systematic review.
A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery.
Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients.
Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study.
抗纖溶藥物
重組活化凝血因子VII（rFVIIa）
凝血因子濃縮劑
去氨加壓素
局部止血藥
利用血液粘彈性檢測辨別外科性出血或凝血病出血
體溫管理（防止低體溫）
Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events. A randomized clinical trial.
Influence of body core temperature on blood loss and transfusion requirements during off-pump coronary artery bypass grafting: A comparison of 3 warming systems.
The effects of mild perioperative hypothermia on blood loss and transfusion requirement.
謹慎進行液體和容量管理
Influence of intraoperative fluid volume on cardiopulmonary bypass hematocrit and blood transfusions in coronary artery bypass surgery.
How good patient blood management leads to excellent outcomes in Jehovah's Witness patients undergoing cardiac surgery.
Strategies to reduce the use of blood products: a European perspective.
Highly positive intraoperative fluid balance during cardiac surgery is associated with adverse outcome.
Effects of a multimodality blood conservation schema toward improvement of intraoperative hemoglobin levels and off-pump transfusions in coronary artery bypass graft surgery.
Management of intraoperative fluid balance and blood conservation techniques in adult cardiac surgery.
Intra-operative intravenous fluid restriction reduces perioperative red blood cell transfusion in elective cardiac surgery, especially in transfusion-prone patients: a prospective, randomized controlled trial.
術中自體血液管理
Reduced use of allogeneic platelets through high-yield perioperative autologous plateletpheresis and reinfusion.
Efficacy and cost-effectiveness of cell saver usage in the repair of thoracic aortic aneurysms and dissections.
Use of minimal extracorporeal circulation improves outcome after heart surgery; a systematic review and meta-analysis of randomized controlled trials.
Minimal extracorporeal circulation reduces the incidence of postoperative major adverse events after elective coronary artery bypass grafting in high-risk patients. A single-institutional prospective randomized study.
Acute normovolemic hemodilution reduces allogeneic red blood cell transfusion in cardiac surgery: a systematic review and meta-analysis of randomized trials.
Evaluation of coagulation factors and platelet function from an off-line modified ultrafiltration technique for post-cardiopulmonary bypass circuit blood recovery.
A new PRECiSe (priming reduced extracorporeal circulation setup) minimizes the need for blood transfusions: first clinical results in coronary artery bypass grafting.
Meta-analysis of randomised trials comparing the effectiveness of miniaturised versus conventional cardiopulmonary bypass in adult cardiac surgery.
Ultrafiltration reduces blood transfusions following cardiac surgery: a meta-analysis.
Prescriptive patient extracorporeal circuit and oxygenator sizing reduces hemodilution and allogeneic blood product transfusion during adult cardiac surgery.
Cell salvage for minimising perioperative allogeneic blood transfusion.
Aortic valve replacement in a dialysis-dependent Jehovah's Witness: successful use of a minicircuit, microplegia, and multimodality blood conservation technique.
Efficacy of intraoperative cell salvage in decreasing perioperative blood transfusion rates in first-time cardiac surgery patients: a retrospective study.
Decreased transfusion requirements with use of acute normovolemic hemodilution in open aortic aneurysm repair.
Minimized perfusion circuits: an alternative in the surgical treatment of Jehovah's Witnesses.
Significant reduction in blood loss in patients undergoing minimal extracorporeal circulation.
Greater volume of acute normovolemic hemodilution may aid in reducing blood transfusions after cardiac surgery.
Is microplegia really superior to standard blood cardioplegia? The results from a meta-analysis.
Novel ultrafiltration technique for blood conservation in cardiac operations.
Impact of minimized extracorporeal circulation on outcome in patients with preoperative anemia undergoing coronary artery bypass surgery.
Does washing swabs increase the efficiency of red cell recovery by cell salvage in aortic surgery?
Transfusion requirements and outcomes in patients undergoing abdominal aortic surgery using intra-operative cell salvage.
Impact of intraoperative high-volume autologous blood collection on allogeneic transfusion during and after cardiac surgery: a propensity score matched analysis.
Retrograde autologous priming in cardiac surgery: results from a systematic review and meta-analysis.
Total cavopulmonary connection in a 35-month-old Jehovah's Witness child.
Retrograde autologous priming of the cardiopulmonary bypass circuit reduces blood transfusion in small adults: a prospective, randomized trial.
Reinfusion of blood within aneurysm sac: a simple method of intraoperative blood conservation in elective abdominal aortic surgery.
Overcoming challenges: the use of minimal extracorporeal circulation in Jehovah's Witnesses undergoing cardiac surgery.
Miniaturized versus conventional cardiopulmonary bypass in high-risk patients undergoing coronary artery bypass surgery.
Transfusion-free anesthetic management for open heart surgery in a neonate—a case report.
Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass surgery.
Beneficial effects of using a minimal extracorporeal circulation system during coronary artery bypass grafting.
Perfusion approaches to blood conservation.
Large volume acute normovolemic hemodilution in patients undergoing cardiac surgery with intermediate-high risk of transfusion: a randomized controlled trial.
Hemodilution in high-risk cardiac surgery: Laboratory values, physiological parameters, and outcomes.
Use of the Hemobag® for modified ultrafiltration in a Jehovah's Witness patient undergoing cardiac surgery.
An analysis of the influence of intra-operative blood salvage and autologous transfusion on reducing the need for allogeneic transfusion in elective infrarenal abdominal aortic aneurysm repair.
Minimized extracorporeal circulation system in coronary artery bypass surgery: a 10-year single-center experience with 2243 patients.
Coronary artery bypass grafting with a minimized cardiopulmonary bypass circuit: a prospective, randomized trial.
Impaired red blood cell deformability after transfusion of stored allogeneic blood but not autologous salvaged blood in cardiac surgery patients.
Retrograde autologous priming reduces transfusion requirements in coronary artery bypass surgery.
The role of cell salvage autotransfusion in abdominal aortic aneurysm surgery.
Effects of a targeted blood management programme on allogeneic blood transfusion in abdominal aortic aneurysm surgery.
Acute normovolemic hemodilution and intraoperative cell salvage in aortic surgery.
Retrograde autologous priming as a safe and easy method to reduce hemodilution and transfusion requirements during cardiac surgery.
Minimised closed circuit coronary artery bypass grafting in the elderly is associated with lower levels of organ-specific biomarkers: a prospective randomised study.
The effect of retrograde autologous priming volume on haemodilution and transfusion requirements during cardiac surgery.
Intraoperative cell salvage is associated with reduced postoperative blood loss and transfusion requirements in cardiac surgery: a cohort study.
The efficacy of an intraoperative cell saver during cardiac surgery: a meta-analysis of randomized trials.
Reduction of allogeneic red blood cell usage during cardiac surgery by an integrated intra- and postoperative blood salvage strategy: results of a randomized comparison.
The effect of acute normovolaemic haemodilution on blood transfusion requirements in abdominal aortic aneurysm repair.
Autologous versus allogeneic transfusion in aortic surgery: a multicenter randomized clinical trial.
Miniaturized cardiopulmonary bypass improves short-term outcome in cardiac surgery: a meta-analysis of randomized controlled studies.
血液回收
急性等容血液稀釋
自體血逆預充
超濾
微型體外循環（灌注）管路
術後血液回收
Reinfusion of mediastinal blood after heart surgery.
Safety and efficacy of perioperative cell salvage and autotransfusion after coronary artery bypass grafting: a randomized trial.
Reduction of allogeneic red blood cell usage during cardiac surgery by an integrated intra- and postoperative blood salvage strategy: results of a randomized comparison.
限制診斷性抽血以避免醫源性貧血
Comparison of structured use of routine laboratory tests or near-patient assessment with clinical judgement in the management of bleeding after cardiac surgery.
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study.
Hospital-acquired anemia: prevalence, outcomes, and healthcare implications.
Contemporary bloodletting in cardiac surgical care.
Predictors and impact of bleeding complications in percutaneous coronary intervention, acute coronary syndromes, and ST-segment elevation myocardial infarction.
Hospital-acquired anemia and in-hospital mortality in patients with acute myocardial infarction.
Diagnostic blood loss from phlebotomy and hospital-acquired anemia during acute myocardial infarction.
Surgical vampires and rising health care expenditure: reducing the cost of daily phlebotomy.
Do blood tests cause anemia in hospitalized patients? The effect of diagnostic phlebotomy on hemoglobin and hematocrit levels.
Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients.
術後貧血管理
Successful repair of a giant abdominal aortoiliac aneurysm in a Jehovah's Witness.
Transfusion-free treatment strategies for acute anemia in critical care.
How do we treat life-threatening anemia in a Jehovah's Witness patient?
Recombinant human erythropoietin use in a critically ill Jehovah's Witness after cardiac surgery.
Successful rescue therapy for severe acute anemia: managing the critically ill Jehovah's Witness.
Intravenous iron following cardiac surgery does not increase the infection rate.
優化病人對貧血的耐受性
Management of a Jehovah's Witness patient with sepsis and profuse bleeding after emergency coronary artery bypass graft surgery: rethinking the critical threshold of oxygen delivery.
Prophylactic hypothermia and neuromuscular blockade to limit myocardial oxygen demand in a critically anemic Jehovah's Witness after emergency surgery.
Care of the injured Jehovah's Witness patient: case report and review of the literature.
Pillar III—optimisation of anaemia tolerance.
容許等容性貧血
Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome.
A prospective, randomized trial limiting perioperative red blood cell transfusions in vascular patients.
Conservative versus liberal red cell transfusion in acute myocardial infarction (the CRIT Randomized Pilot Study).
Restrictive blood transfusion practices are associated with improved patient outcomes.
Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases?
Blood transfusion and 30-day mortality in patients with coronary artery disease and anemia following noncardiac surgery.
Impact of transfusion policy on acute coronary syndrome after major vascular reconstruction.
Restrictive or liberal red-cell transfusion for cardiac surgery.
Postoperative anemia and exercise tolerance after cardiac operations in patients with