Betatalassemia intermediária e menor
Indução farmacológica da síntese da hemoglobina fetal
Terapia com hidroxiureia (hidroxicarbamida)
Optimizing the dose of hydroxyurea therapy for patients with β-thalassemia intermedia (Hb E-β-thalassemia): a single center study from eastern India. (abre nova janela)
Fonte: Hemoglobin 2014;38(1):44-8.
Hydroxyurea in thalassemia intermedia--a promising therapy. (abre nova janela)
Fonte: Ann Hematol 2005;84(7):441-6.
Effect of hydroxyurea on the transfusion requirements in patients with severe HbE-beta-thalassaemia: a genotypic and phenotypic study. (abre nova janela)
Fonte: J Clin Pathol 2010;63(2):147-50.
Echocardiographic finding in beta-thalassemia intermedia and major: absence of pulmonary hypertension following hydroxyurea treatment in beta-thalassemia intermedia. (abre nova janela)
Fonte: Eur J Haematol 2009;82(3):213-8.
Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia. (abre nova janela)
Fonte: Eur J Haematol 2010;84(1):52-8.
Reduction of the clinical severity of sickle cell/beta-thalassemia with hydroxyurea: the experience of a single center in Greece. (abre nova janela)
Fonte: Blood Cells Mol Dis 2000;26(5):453-66.
Fetal globin stimulant therapies in the beta-hemoglobinopathies: principles and current potential. (abre nova janela)
Fonte: Pediatr Ann 2008;37(5):339-46.
Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment. (abre nova janela)
Fonte: Ann N Y Acad Sci 2005;1054:250-6.
Eritropoetina recombinante (isolada ou combinada com outros agentes)
Treatment of beta-thalassemia patients with recombinant human erythropoietin: effect on transfusion requirements and soluble adhesion molecules. (abre nova janela)
Fonte: Acta Haematol 2004;111(4):189-95.
Efficacy of erythropoietin on dialysis in patients with beta thalassemia minor. (abre nova janela)
Fonte: Blood Purif 2004;22(5):453-60.
The role of recombinant human erythropoietin in the treatment of thalassemia. (abre nova janela)
Fonte: Ann N Y Acad Sci 1998;850:129-38.
Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes. (abre nova janela)
Fonte: Br J Haematol 2011;154(2):281-4.
The emerging role of fetal hemoglobin induction in non-transfusion-dependent thalassemia. (abre nova janela)
Fonte: Blood Rev 2012;26 Suppl 1:S35-9.