Thalasemia Beta Mayor (Anak-Anak)
Induksi Sintesis Hemoglobin Janin dengan Obat-obatan
Terapi Hidroksiurea (Hidroksicarbamide)
Efficacy of hydroxyurea in providing transfusion independence in β-thalassemia.
Sumber: J Pediatr Hematol Oncol 2011;33(5):339-43.
Index: PubMed 21602718
DOI: 10.1097/MPH.0b013e31821b0770
Gγ-Xmn I polymorphism: a significant determinant of β-thalassemia treatment without blood transfusion.
Sumber: J Pediatr Hematol Oncol 2013;35(4):e153-6.
Index: PubMed 23389500
DOI: 10.1097/MPH.0b013e31827e8662
Efficacy of hydroxyurea (HU) in reduction of pack red cell (PRC) transfusion requirement among children having beta-thalassemia major: Karachi HU trial (KHUT).
Sumber: J Pediatr Hematol Oncol 2007;29(11):743-6.
Index: PubMed 17984691
DOI: 10.1097/MPH.0b013e318157fd75
Hydroxyurea can eliminate transfusion requirements in children with severe beta-thalassemia.
Sumber: Blood 2003;102(4):1529-30.
Index: PubMed 12702505
DOI: 10.1182/blood-2003-01-0117
Decreased transfusion needs associated with hydroxyurea therapy in Algerian patients with thalassemia major or intermedia.
Sumber: Transfusion 2007;47(10):1830-6.
Index: PubMed 17880608
DOI: 10.1111/j.1537-2995.2007.01399.x
Hydroxyurea can reduce or eliminate transfusion requirements in children with major and intermediate thalassemia.
Sumber: Iran J Blood Cancer 2009;1(4):147-50.
Index: IMEMR 107228
Genotype-phenotype relationship of patients with β-thalassemia taking hydroxyurea: a 13-year experience in Iran.
Sumber: Int J Hematol 2012;95(1):51-6.
Index: PubMed 22180324
DOI: 10.1007/s12185-011-0985-6
Fetal globin stimulant therapies in the beta-hemoglobinopathies: principles and current potential.
Sumber: Pediatr Ann 2008;37(5):339-46.
Index: PubMed 18543545
Response to hydroxyurea treatment in Iranian transfusion-dependent beta-thalassemia patients.
Sumber: Haematologica 2004;89(10):1172-8.
Index: PubMed 15477200
Hydroxyurea therapy in 49 patients with major beta-thalassemia.
Sumber: Arch Iran Med 2009;12(3):295-7.
Index: PubMed 19400608
Rekombinan Eritropoietin (Sendiri atau Kombinasi dengan Obat Lain)
Use of hydroxyurea and recombinant erythropoietin in management of homozygous ß⁰ thalassemia.
Sumber: J Pediatr Hematol Oncol 2002;24(9):777-8.
Index: PubMed 12468925
Termination of transfusion dependence in beta-thalassemia: two-year experience with recombinant human erythropoietin.
Sumber: Pediatr Hematol Oncol 1997;14(3):285-7.
Index: PubMed 9185215
Obat-obat Lain
Fetal globin gene inducers: novel agents and new potential.
Sumber: Ann N Y Acad Sci 2010;1202:158-64.
Index: PubMed 20712788
DOI: 10.1111/j.1749-6632.2010.05593.x