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Travma ve Acil Tıp

Uygun Hemostaz (Kanamanın Durması)

Antifibrinolitik İlaçlar

Alternatives to allogeneic platelet transfusion. (opens new window)

Desborough MJ, Smethurst PA, Estcourt LJ, Stanworth SJ.

Kaynak‎: Br J Haematol 2016;175(3):381-92.

İndeks‎: PubMed 27650431

DOI‎: 10.1111/bjh.14338

https://www.ncbi.nlm.nih.gov/pubmed/27650431 (opens new window)

Antifibrinolytic drugs for acute traumatic injury. (opens new window)

Ker K, Roberts I, Shakur H, Coats TJ.

Kaynak‎: Cochrane Database Syst Rev 2015;(5):CD004896.

İndeks‎: PubMed 25956410

DOI‎: 10.1002/14651858.CD004896.pub4

https://www.ncbi.nlm.nih.gov/pubmed/25956410 (opens new window)

Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study. (opens new window)

Morrison JJ, Ross JD, Dubose JJ, Jansen JO, Midwinter MJ, Rasmussen TE.

Kaynak‎: JAMA Surg 2013;148(3):218-25.

İndeks‎: PubMed 23670117

DOI‎: 10.1001/jamasurg.2013.764

https://www.ncbi.nlm.nih.gov/pubmed/23670117 (opens new window)

The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. (opens new window)

Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt BJ, Morales C, Perel P, Prieto-Merino D, Woolley T; CRASH-2 collaborators.

Kaynak‎: Lancet 2011;377(9771):1096-101, 1101.e1-2.

İndeks‎: PubMed 21439633

DOI‎: 10.1016/S0140-6736(11)60278-X

https://www.ncbi.nlm.nih.gov/pubmed/21439633 (opens new window)

Rekombinant Aktive Faktör VII (rFVIIa)

The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (opens new window)

Boffard KD, Choong PI, Kluger Y, Riou B, Rizoli SB, Rossaint R, Warren B; NovoSeven Trauma Study Group.

Kaynak‎: Transfusion 2009;49 Suppl 5:240S-7S.

İndeks‎: PubMed 19954486

DOI‎: 10.1111/j.1537-2995.2008.01987.x

https://www.ncbi.nlm.nih.gov/pubmed/19954486 (opens new window)

Pıhtılaşma Faktörü Konsantreleri

The exclusive use of coagulation factor concentrates enables reversal of coagulopathy and decreases transfusion rates in patients with major blunt trauma. (opens new window)

Innerhofer P, Westermann I, Tauber H, Breitkopf R, Fries D, Kastenberger T, El Attal R, Strasak A, Mittermayr M.

Kaynak‎: Injury 2013;44(2):209-16.

İndeks‎: PubMed 23000050

DOI‎: 10.1016/j.injury.2012.08.047

https://www.ncbi.nlm.nih.gov/pubmed/23000050 (opens new window)

Desmopresin

Desmopressin is a transfusion sparing option to reverse platelet dysfunction in patients with severe traumatic brain injury. (opens new window)

Furay EJ, Daley MJ, Satarasinghe P, Lara S, Aydelotte JD, Teixeira PG, Coopwood TB, Ali S, Brown CVR

Kaynak‎: J Trauma Acute Care Surg 2020;88(1):80-6.

İndeks‎: PubMed 31688782

DOI‎: 10.1097/TA.0000000000002521

https://www.ncbi.nlm.nih.gov/pubmed/31688782 (opens new window)

Cerrahiye ya da Pıhtılaşma Bozukluğuna Bağlı Kanamanın Tespitinde Viskoelastik Testler

Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy. (opens new window)

Brenni M, Worn M, Brüesch M, Spahn DR, Ganter MT.

Kaynak‎: Acta Anaesthesiol Scand 2010;54(1):111-7.

İndeks‎: PubMed 19860752

DOI‎: 10.1111/j.1399-6576.2009.02132.x

https://www.ncbi.nlm.nih.gov/pubmed/19860752 (opens new window)