Pular para conteúdo

Talassemia Beta Intermediária e Menor\_(Pediátrica)

Indução farmacológica da síntese da hemoglobina fetal

Terapia com Hidroxiureia (Hidroxicarbamida)\_

Optimizing the dose of hydroxyurea therapy for patients with β-thalassemia intermedia (Hb E-β-thalassemia): a single center study from eastern India. (abre nova janela)

Bohara VV, Ray S, Chakrabarti P, Ray SS, Nath UK, Chaudhuri U.

Fonte‎: Hemoglobin 2014;38(1):44-8.

Indexado‎: PubMed 24144212

DOI‎: 10.3109/03630269.2013.845844

https://www.ncbi.nlm.nih.gov/pubmed/24144212 (abre nova janela)

Hydroxyurea in thalassemia intermedia--a promising therapy. (abre nova janela)

Dixit A, Chatterjee TC, Mishra P, Choudhry DR, Mahapatra M, Tyagi S, Kabra M, Saxena R, Choudhry VP.

Fonte‎: Ann Hematol 2005;84(7):441-6.

Indexado‎: PubMed 15838670

DOI‎: 10.1007/s00277-005-1026-4

https://www.ncbi.nlm.nih.gov/pubmed/15838670 (abre nova janela)

Effect of hydroxyurea on the transfusion requirements in patients with severe HbE-beta-thalassaemia: a genotypic and phenotypic study. (abre nova janela)

Italia KY, Jijina FF, Merchant R, Panjwani S, Nadkarni AH, Sawant PM, Nair SB, Ghosh K, Colah RB.

Fonte‎: J Clin Pathol 2010;63(2):147-50.

Indexado‎: PubMed 20154037

DOI‎: 10.1136/jcp.2009.070391

https://www.ncbi.nlm.nih.gov/pubmed/20154037 (abre nova janela)

Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia. (abre nova janela)

Karimi M, Mohammadi F, Behmanesh F, Samani SM, Borzouee M, Amoozgar H, Haghpanah S.

Fonte‎: Eur J Haematol 2010;84(1):52-8.

Indexado‎: PubMed 19799627

DOI‎: 10.1111/j.1600-0609.2009.01356.x

https://www.ncbi.nlm.nih.gov/pubmed/19799627 (abre nova janela)

Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment. (abre nova janela)

Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP.

Fonte‎: Ann N Y Acad Sci 2005;1054:250-6.

Indexado‎: PubMed 16339672

DOI‎: 10.1196/annals.1345.031

https://www.ncbi.nlm.nih.gov/pubmed/16339672 (abre nova janela)

Eritropoetina Recombinante (Isolada ou Combinada com Outros Agentes)

Treatment of beta-thalassemia patients with recombinant human erythropoietin: effect on transfusion requirements and soluble adhesion molecules. (abre nova janela)

Chaidos A, Makis A, Hatzimichael E, Tsiara S, Gouva M, Tzouvara E, Bourantas KL.

Fonte‎: Acta Haematol 2004;111(4):189-95.

Indexado‎: PubMed 15153710

DOI‎: 10.1159/000077551

https://www.ncbi.nlm.nih.gov/pubmed/15153710 (abre nova janela)

Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes. (abre nova janela)

Singer ST, Vichinsky EP, Sweeters N, Rachmilewitz E.

Fonte‎: Br J Haematol 2011;154(2):281-4.

Indexado‎: PubMed 21496003

DOI‎: 10.1111/j.1365-2141.2011.08617.x

https://www.ncbi.nlm.nih.gov/pubmed/21496003 (abre nova janela)

The emerging role of fetal hemoglobin induction in non-transfusion-dependent thalassemia. (abre nova janela)

Thein SL.

Fonte‎: Blood Rev 2012;26 Suppl 1:S35-9.

Indexado‎: PubMed 22631042

DOI‎: 10.1016/S0268-960X(12)70011-5

https://www.ncbi.nlm.nih.gov/pubmed/22631042 (abre nova janela)

Outros Agentes

Fetal hemoglobin inducers from the natural world: a novel approach for identification of drugs for the treatment of {beta}-thalassemia and sickle-cell anemia. (abre nova janela)

Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R.

Fonte‎: Evid Based Complement Alternat Med 2009;6(2):141-51.

Indexado‎: PubMed 18955291

DOI‎: 10.1093/ecam/nem139

https://www.ncbi.nlm.nih.gov/pubmed/18955291 (abre nova janela)

A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia. (abre nova janela)

Fucharoen S, Inati A, Siritanaratku N, Thein SL, Wargin WC, Koussa S, Taher A, Chaneim N, Boosalis M, Berenson R, Perrine SP.

Fonte‎: Br J Haematol 2013;161(4):587-93.

Indexado‎: PubMed 23530969

DOI‎: 10.1111/bjh.12304

https://www.ncbi.nlm.nih.gov/pubmed/23530969 (abre nova janela)

Butyric acid: what is the future for this old substance? (abre nova janela)

Sossai P.

Fonte‎: Swiss Med Wkly 2012;142:w13596.

Indexado‎: PubMed 22674349

DOI‎: 10.4414/smw.2012.13596

https://www.ncbi.nlm.nih.gov/pubmed/22674349 (abre nova janela)