Perioperatieve zorg (kindergeneeskunde)
Management en optimalisatie van hemostase
Antifibrinolytica
A systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use. (opent nieuw venster)
Bron: Pediatr Surg Int 2012;28(11):1059-69.
Use of tranexamic acid as a rescue measure to achieve hemostasis after massive blood loss in a pediatric neurosurgical patient. (opent nieuw venster)
Bron: J Neurosurg Anesthesiol 2011;23(4):376-7.
Aprotinin, transfusions, and kidney injury in neonates and infants undergoing cardiac surgery. (opent nieuw venster)
Bron: Br J Anaesth 2012;108(5):830-7.
A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery. [Chirurgie de la scoliose chez un enfant Témoin de Jéhovah souffrant d’hémophilie B et présentant des inhibiteurs du facteur IX.] [English, French abstract] (opent nieuw venster)
Bron: Can J Anaesth 2008;55(1):47-51.
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study. (opent nieuw venster)
Bron: Spine (Phila Pa 1976) 2008;33(24):2577-80.
The efficacy of antifibrinolytic drugs in children undergoing noncardiac surgery: a systematic review of the literature. (opent nieuw venster)
Bron: Anesth Analg 2014;118(3):628-36.
The effect of Amicar on perioperative blood loss in idiopathic scoliosis: the results of a prospective, randomized double-blind study. (opent nieuw venster)
Bron: Spine 2004;29(3):233-8.
A randomized control trial to verify the efficacy of pre-operative intravenous tranexamic acid in the control of tonsillectomy bleeding. (opent nieuw venster)
Bron: Indian J Otolaryngol Head Neck Surg 2011;63(1):20-6.
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial. (opent nieuw venster)
Bron: Anesthesiology 2011;114(4):862-71.
Tranexamic acid is efficacious at decreasing the rate of blood loss in adolescent scoliosis surgery: a randomized placebo-controlled trial. (opent nieuw venster)
Bron: J Bone Joint Surg Am 2018;100(23):2024-32.
Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. (opent nieuw venster)
Bron: J Thorac Cardiovasc Surg 2012;143(5):1069-76.
The effect of prophylactic use of antifibrinolytics during pediatric non-cardiac surgeries on bleeding and transfusions: a systematic review and meta-analysis. (opent nieuw venster)
Bron: Paediatr Anaesth 2025;35(8):668-83.
Anesthetic management for transfusion-free Rastelli's procedure in a pediatric Jehovah's Witness patient. (opent nieuw venster)
Bron: Korean J Anesthesiol 2013;65(6 Suppl):S87-8.
The safety and efficacy of antifibrinolytic therapy in neonatal cardiac surgery. (opent nieuw venster)
Bron: PLoS One 2015;10(5):e0126514.
Tranexamic acid versus ɛ-aminocaproic acid: efficacy and safety in paediatric cardiac surgery. (opent nieuw venster)
Bron: Eur J Cardiothorac Surg 2011;39(6):892-7.
Effective pediatric blood management in craniosynostosis surgery: a long-term update. (opent nieuw venster)
Bron: J Craniofac Surg 2025; 01;36(1):111-14.
Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures. (opent nieuw venster)
Bron: Spine (Phila Pa 1976) 2012;37(23):E1459-63.
Comparative analysis of antifibrinolytic medications in pediatric heart surgery. (opent nieuw venster)
Bron: J Thorac Cardiovasc Surg 2012;143(3):550-7.
Use of tranexamic acid in infants undergoing choroid plexus papilloma surgery: a report of two cases. (opent nieuw venster)
Bron: Paediatr Anaesth 2014;24(7):791-3.
The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis. (opent nieuw venster)
Bron: Pediatr Crit Care Med 2009;10(2):182-90.
The role of Amicar in same-day anterior and posterior spinal fusion for idiopathic scoliosis. (opent nieuw venster)
Bron: Spine (Phila Pa 1976) 2008;33(20):2237-42.
Comparison of three dose regimens of aprotinin in infants undergoing the arterial switch operation. (opent nieuw venster)
Bron: Ann Card Anaesth 2010;13(2):110-5.
Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass. (opent nieuw venster)
Bron: Anesthesiology 2015;122(4):746-58.
Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? (opent nieuw venster)
Bron: Spine (Phila Pa 1976) 2012;37(21):E1336-42.
Recombinante geactiveerde factor VII (rFVIIa)
Pediatric off-label use of recombinant factor VIIa. (opent nieuw venster)
Bron: Pediatrics 2009;123(3):1066-72.
Recombinant activated factor VII usage in life threatening hemorrhage: a pediatric experience. (opent nieuw venster)
Bron: Indian J Pediatr 2011;78(8):961-8.
Recombinant activated factor VII (rFVIIa) treatment in infants with hemorrhage. (opent nieuw venster)
Bron: Paediatr Anaesth 2006;16(10):1042-6.
A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery. [Chirurgie de la scoliose chez un enfant Témoin de Jéhovah souffrant d’hémophilie B et présentant des inhibiteurs du facteur IX.] [English, French abstract] (opent nieuw venster)
Bron: Can J Anaesth 2008;55(1):47-51.
Review of the off-label use of recombinant activated factor VII in pediatric cardiac surgery patients. (opent nieuw venster)
Bron: Anesth Analg 2012;115(2):364-78.
The use of rFVIIa in non-haemophilia bleeding conditions in paediatrics. A systematic review. (opent nieuw venster)
Bron: Thromb Haemost 2004;92(4):738-46.
Use of recombinant activated factor VII for controlling refractory postoperative bleeding in children undergoing cardiac surgery with cardiopulmonary bypass. (opent nieuw venster)
Bron: J Cardiothorac Vasc Anesth 2011;25(6):987-94.
Recombinant activated factor VII for hemorrhage after pediatric cardiac surgery. (opent nieuw venster)
Bron: Asian Cardiovasc Thorac Ann 2012;20(1):19-23.
Single-center experience: use of recombinant factor VIIa for acute life-threatening bleeding in children without congenital hemorrhagic disorder. (opent nieuw venster)
Bron: Pediatr Hematol Oncol 2008;25(4):301-11.
Off-label use of rFVIIa in children with excessive bleeding: a consecutive study of 153 off-label uses in 139 children. (opent nieuw venster)
Bron: Pediatr Blood Cancer 2009;53(2):179-83.
Coagulatiefactorconcentraten
Emergent pediatric anticoagulation reversal using a 4-factor prothrombin complex concentrate. (opent nieuw venster)
Bron: Am J Emerg Med 2016;34(6):1182.e1-2.
Perioperative monitoring of thromboelastograph on blood protection and recovery for severely cyanotic patients undergoing complex cardiac surgery. (opent nieuw venster)
Bron: Artif Organs 2010;34(11):955-60.
Plasma fibrinogen concentration is correlated with postoperative blood loss in children undergoing cardiac surgery. A retrospective review. (opent nieuw venster)
Bron: Eur J Anaesthesiol 2014;31(6):317-26.
Hemostatic effects of fibrinogen concentrate compared with cryoprecipitate in children after cardiac surgery: a randomized pilot trial. (opent nieuw venster)
Bron: J Thorac Cardiovasc Surg 2014;148(4):1647-55.
Four-factor prothrombin complex concentrates in paediatric patients—a retrospective case series. (opent nieuw venster)
Bron: Vox Sang 2016;110(3):253-7.
Desmopressine
Visco-elastische tests ter vaststelling van chirurgische of coagulopathische bloedingen
Utility of Sonoclot analysis and tranexamic acid in tetralogy of Fallot patients undergoing intracardiac repair. (opent nieuw venster)
Bron: Ann Card Anaesth 2012;15(1):26-31.
Perioperative bleeding management in pediatric patients. (opent nieuw venster)
Bron: Curr Opin Anaesthesiol 2016;29(3):352-8.
Management of dilutional coagulopathy during pediatric major surgery. (opent nieuw venster)
Bron: Transfus Med Hemother 2012;39(2):114-9.
Higher fibrinogen concentrations for reduction of transfusion requirements during major paediatric surgery: a prospective randomised controlled trial. (opent nieuw venster)
Bron: Br J Anaesth 2015;115(2):234-43.
Thromboelastometry-guided intraoperative haemostatic management reduces bleeding and red cell transfusion after paediatric cardiac surgery. (opent nieuw venster)
Bron: Br J Anaesth 2015;114(1):91-102.
Cardiac surgery without blood products in a Jehovah's Witness child with factor VII deficiency. (opent nieuw venster)
Bron: J Cardiothorac Vasc Anesth 2012;26(4):651-3.
Activated coagulation time vs. intrinsically activated modified rotational thromboelastometry in assessment of hemostatic disturbances and blood loss after protamine administration in elective cardiac surgery: analysis from the clinical trial (NCT01281397). (opent nieuw venster)
Bron: J Cardiothorac Surg 2014;9:129.