Management en optimalisatie van hemostase

Antifibrinolytica

Alternatives to allogeneic platelet transfusion. (opent nieuw venster)

Desborough MJ, Smethurst PA, Estcourt LJ, Stanworth SJ.

Bron‎: Br J Haematol 2016;175(3):381-92.

Tranexamic acid in patients undergoing noncardiac surgery. (opent nieuw venster)

Devereaux PJ, Marcucci M, Painter TW, Conen D, Lomivorotov V, Sessler DI, Chan MTV, Borges FK, Martínez-Zapata MJ, Wang CY, Xavier D, Ofori SN, Wang MK, Efremov S, Landoni G, Kleinlugtenbelt YV, Szczeklik W, Schmartz D, Garg AX, Short TG, Wittmann M, Meyhoff CS, Amir M, Torres D, Patel A, Duceppe E, Ruetzler K, Parlow JL, Tandon V, Fleischmann E, Polanczyk CA, Lamy A, Astrakov SV, Rao M, Wu WKK, Bhatt K, de Nadal M, Likhvantsev VV, Paniagua P, Aguado HJ, Whitlock RP, McGillion MH, Prystajecky M, Vincent J, Eikelboom J, Copland I, Balasubramanian K, Turan A, Bangdiwala SI, Stillo D, Gross PL, Cafaro T, Alfonsi P, Roshanov PS, Belley-Côté EP, Spence J, Richards T, VanHelder T, McIntyre W, Guyatt G, Yusuf S, Leslie K; POISE-3 Investigators

Bron‎: N Engl J Med. 2022;386(21):1986-97.

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. (opent nieuw venster)

Henry DA, Carless PA, Moxey AJ, O'Connell D, Stokes BJ, Fergusson DA, Ker K.

Bron‎: Cochrane Database Syst Rev 2011;(3):CD001886.

A single preoperative dose of tranexamic acid reduces perioperative blood loss: a meta-analysis. (opent nieuw venster)

Heyns M, Knight P, Steve AK, Yeung JK

Bron‎: Ann Surg 2021;273(1):75-81.

Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin. (opent nieuw venster)

Howell N, Senanayake E, Freemantle N, Pagano D.

Bron‎: J Thorac Cardiovasc Surg 2013;145(1):234-40.

Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. (opent nieuw venster)

Ker K, Edwards P, Perel P, Shakur H, Roberts I.

Bron‎: BMJ 2012;344:e3054.

Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss. (opent nieuw venster)

Ker K, Prieto-Merino D, Roberts I.

Bron‎: Br J Surg 2013;100(10):1271-9.

Safety and efficacy of tranexamic acid in general surgery. (opent nieuw venster)

Park LJ, Marcucci M, Ofori SN, Borges FK, Nenshi R, Kanstrup CTB, Rosen M, Landoni G, Lomivorotov V, Painter TW, Xavier D, Martinez-Zapata MJ, Szczeklik W, Meyhoff CS, Chan MTV, Simunovic M, Bogach J, Serrano PE, Balasubramanian K, Cadeddu M, Yang I, Kim WH, Devereaux PJ

Bron‎: JAMA Surg 2025;160(3):267-74.

Association of intravenous tranexamic acid with thromboembolic events and mortality: a systematic review, meta-analysis, and meta-regression. (opent nieuw venster)

Taeuber I, Weibel S, Herrmann E, Neef V, Schlesinger T, Kranke P, Messroghli L, Zacharowski K, Choorapoikayil S, Meybohm P

Bron‎: JAMA Surg 2021;156(6):e210884.

Oral is as effective as intravenous tranexamic acid at reducing blood loss in thoracolumbar spinal fusions: a prospective randomized trial. (opent nieuw venster)

Yu CC, Fidai M, Washington T, Bartol S, Graziano G

Bron‎: Spine 2022;47(2):91-8.

Recombinante geactiveerde factor VII (rFVIIa)

Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa? (opent nieuw venster)

Ballen J, Raabe M, Muirhead B.

Bron‎: Can J Anaesth 2006;53(4):353-6.

The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (opent nieuw venster)

Boffard KD, Choong PI, Kluger Y, Riou B, Rizoli SB, Rossaint R, Warren B; NovoSeven Trauma Study Group.

Bron‎: Transfusion 2009;49 Suppl 5:240S-7S.

Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery. (opent nieuw venster)

Karkouti K, Beattie WS, Arellano R, Aye T, Bussieres JS, Callum JL, Cheng D, Heinrich L, Kent B, Lee TW, MacAdams C, Mazer CD, Muirhead B, Rochon AG, Rubens FD, Sawchuk C, Wang S, Waters T, Wong BI, Yau TM.

Bron‎: Circulation 2008;118(4):331-8.

Recombinant factor VIIa as last-resort treatment of desperate haemorrhage. (opent nieuw venster)

Palmason R, Vidarsson B, Sigvaldason K, Ingimarsson JP, Gudbjartsson T, Sigurdsson GH, Onundarson PT.

Bron‎: Acta Anaesthesiol Scand 2012;56(5):636-44.

Coagulatiefactorconcentraten

Prophylactic use of factor IX concentrate in a Jehovah's Witness patient. (opent nieuw venster)

Bolliger D, Sreeram G, Duncan A, Molinaro RJ, Szlam F, Chen EP, Tanaka KA.

Bron‎: Ann Thorac Surg 2009;88(5):1666-8.

Bloodless orthotopic heart transplantation in a Jehovah's Witness. (opent nieuw venster)

Dallas T, Welsby I, Bottiger B, Milano C, Daneshmand M, Guinn N.

Bron‎: A A Case Rep 2015;4(10):140-2.

Fibrinogen replacement therapy: a critical review of the literature. (opent nieuw venster)

Franchini M, Lippi G.

Bron‎: Blood Transfus 2012;10(1):23-7.

First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (opent nieuw venster)

Görlinger K, Dirkmann D, Hanke AA, Kamler M, Kottenberg E, Thielmann M, Jakob H, Peters J.

Bron‎: Anesthesiology 2011;115(6):1179-91.

Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study. (opent nieuw venster)

Karlsson M, Ternström L, Hyllner M, Baghaei F, Flinck A, Skrtic S, Jeppsson A.

Bron‎: Thromb Haemost 2009;102(1):137-44.

Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy. (opent nieuw venster)

Levy JH, Welsby I, Goodnough LT.

Bron‎: Transfusion 2014;54(5):1389-405.

Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial. (opent nieuw venster)

Rahe-Meyer N, Solomon C, Hanke A, Schmidt DS, Knoerzer D, Hochleitner G, Sørensen B, Hagl C, Pichlmaier M.

Bron‎: Anesthesiology 2013;118(1):40-50.

Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate. (opent nieuw venster)

Robblee JA, Wilkes PR, Dickie SJ, Rubens FD, Bormanis J.

Bron‎: Can J Anaesth 2012;59(3):299-303.

Desmopressine

Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry. (opent nieuw venster)

Hanke AA, Dellweg C, Kienbaum P, Weber CF, Görlinger K, Rahe-Meyer N.

Bron‎: Anaesthesia 2010;65(7):688-91.

Visco-elastische tests ter vaststelling van chirurgische of coagulopathische bloedingen

Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology. (opent nieuw venster)

Kozek-Langenecker SA, Afshari A, Albaladejo P, Santullano CA, De Robertis E, Filipescu DC, Fries D, Görlinger K, Haas T, Imberger G, Jacob M, Lancé M, Llau J, Mallett S, Meier J, Rahe-Meyer N, Samama CM, Smith A, Solomon C, Van der Linden P, Wikkelsø AJ, Wouters P, Wyffels P.

Bron‎: Eur J Anaesthesiol 2013;30(6):270-382.

Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate. (opent nieuw venster)

Schöchl H, Forster L, Woidke R, Solomon C, Voelckel W.

Bron‎: Anaesthesia 2010;65(2):199-203.

Medische informatie voor artsen

Management en optimalisatie van hemostase

Antifibrinolytica

Alternatives to allogeneic platelet transfusion. (opent nieuw venster)

Tranexamic acid in patients undergoing noncardiac surgery. (opent nieuw venster)

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. (opent nieuw venster)

A single preoperative dose of tranexamic acid reduces perioperative blood loss: a meta-analysis. (opent nieuw venster)

Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin. (opent nieuw venster)

Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. (opent nieuw venster)

Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss. (opent nieuw venster)

Safety and efficacy of tranexamic acid in general surgery. (opent nieuw venster)

Association of intravenous tranexamic acid with thromboembolic events and mortality: a systematic review, meta-analysis, and meta-regression. (opent nieuw venster)

Oral is as effective as intravenous tranexamic acid at reducing blood loss in thoracolumbar spinal fusions: a prospective randomized trial. (opent nieuw venster)

Recombinante geactiveerde factor VII (rFVIIa)

Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa? (opent nieuw venster)

The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (opent nieuw venster)

Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery. (opent nieuw venster)

Recombinant factor VIIa as last-resort treatment of desperate haemorrhage. (opent nieuw venster)

Coagulatiefactorconcentraten

Prophylactic use of factor IX concentrate in a Jehovah's Witness patient. (opent nieuw venster)

Bloodless orthotopic heart transplantation in a Jehovah's Witness. (opent nieuw venster)

Fibrinogen replacement therapy: a critical review of the literature. (opent nieuw venster)

First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (opent nieuw venster)

Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study. (opent nieuw venster)

Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy. (opent nieuw venster)

Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial. (opent nieuw venster)

Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate. (opent nieuw venster)

Desmopressine

Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry. (opent nieuw venster)

Visco-elastische tests ter vaststelling van chirurgische of coagulopathische bloedingen

Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology. (opent nieuw venster)

Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate. (opent nieuw venster)

Ziekenhuiscontactcomité (zcc)

Medische informatiepakketten

Video’s

Interview Pia Di Benedetto, MD

Management en optimalisatie van hemostase

Antifibrinolytica

Recombinante geactiveerde factor VII (rFVIIa)

Coagulatiefactorconcentraten

Desmopressine

Visco-elastische tests ter vaststelling van chirurgische of coagulopathische bloedingen

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