外傷・救急医療
止血の管理と最適化
抗線溶薬
Strategies to prevent blood loss and reduce transfusion in emergency general surgery, WSES-AAST consensus paper. (新しいタブで開く)
出典: World J Emerg Surg 2024;19(1):26.
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. (新しいタブで開く)
出典: Lancet 2019;394(10210):1713-23.
Alternatives to allogeneic platelet transfusion. (新しいタブで開く)
出典: Br J Haematol 2016;175(3):381-92.
Antifibrinolytic drugs for acute traumatic injury. (新しいタブで開く)
出典: Cochrane Database Syst Rev 2015;(5):CD004896.
Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study. (新しいタブで開く)
出典: JAMA Surg 2013;148(3):218-25.
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. (新しいタブで開く)
出典: Lancet 2011;377(9771):1096-101, 1101.e1-2.
遺伝子組換え活性型血液凝固第Ⅶ因子製剤(rFVIIa)
Efficacy of recombinant activated Factor VII in patients with massive uncontrolled bleeding: a retrospective observational analysis. (新しいタブで開く)
出典: Transfusion 2009;49(3):570-7.
The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (新しいタブで開く)
出典: Transfusion 2009;49 Suppl 5:240S-7S.
濃縮凝固因子製剤
デスモプレシン
Strategies to prevent blood loss and reduce transfusion in emergency general surgery, WSES-AAST consensus paper. (新しいタブで開く)
出典: World J Emerg Surg 2024;19(1):26.
Desmopressin is a transfusion sparing option to reverse platelet dysfunction in patients with severe traumatic brain injury. (新しいタブで開く)
出典: J Trauma Acute Care Surg 2020;88(1):80-6.
外科的出血か凝固異常による出血かを同定するための血液粘弾性試験
Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy. (新しいタブで開く)
出典: Acta Anaesthesiol Scand 2010;54(1):111-7.
