内容へ
サイトの言語を変える
閉じる
メニューを表示
臨床医
さらに表示
内科と外科
小児科
疾患と病態
生命倫理と法
医学情報
ビデオ
地元の代表者と連絡をお取りください
閉じる
言語を選ぶ
日本語
臨床医
臨床医のための医学情報
内科と外科
小児科
疾患と病態
生命倫理と法
地元の代表者と連絡をお取りください
医学情報
ビデオ
閉じる
臨床医のための医学情報
定評のある医学雑誌の査読された論文。この論文には,さまざまな治療や手術における同種血輸血に代わる治療ストラテジーと,そのストラテジーを支持するエビデンスが示されています。
お問い合わせ
検索
治療前の患者の評価と輸血リスクの評価
Predictive factors for perioperative blood transfusions in partial nephrectomy for renal masses.
Drug interactions with phytotherapeutics in oncology.
Factors associated with the avoidance of red blood cell transfusion after hematopoietic stem cell transplantation.
Clinical factors affecting engraftment and transfusion needs in SCT: a single-center retrospective analysis.
Trends and risk factors for transfusion in hepatopancreatobiliary surgery.
Potential interactions with anticancer agents: a cross-sectional study.
治療前の計画と患者の状態の最適化
Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients.
Intraoperative bleeding and haemostasis during pelvic surgery for locally advanced or recurrent rectal cancer: a prospective evaluation.
A cohort investigation of anaemia, treatment and the use of allogeneic blood transfusion in colorectal cancer surgery.
The theory and practice of bloodless surgery.
Non-blood medical care in gynecologic oncology: a review and update of blood conservation management schemes.
Effects of trilaciclib on chemotherapy-induced myelosuppression and patient-reported outcomes in patients with extensive-stage small cell lung cancer: Pooled results from three phase ii randomized, double-blind, placebo-controlled studies.
Adverse effects on hemostatic function of drugs used in hematologic malignancies.
集学的,職種横断的な,個別化されたアプローチ
Pancreaticoduodenectomy without homologous blood transfusion in an anemic Jehovah's Witness.
Complex liver resection for a large intrahepatic cholangiocarcinoma in a Jehovah's Witness: a strategy to avoid transfusion.
Long-lasting extreme anemia during the therapy of acute lymphoblastic leukemia in a Jehovah's Witness patient.
Leczenie ostrej białaczki u Świadków Jehowy—opis przypadku i przegląd piśmiennictwa. [Treatment of acute leukemia in Jehovah's Witnesses—a case report and review of the literature.] [Polish, English abstract]
Autologous stem-cell transplantation without hematopoietic support for the treatment of hematologic malignancies in Jehovah's Witnesses.
Impact of a patient blood management program and an outpatient anemia management protocol on red cell transfusions in oncology inpatients and outpatients.
A multidisciplinary approach to gastrointestinal bleeding in cancer patients.
エホバの証人に対して無輸血手術を行った褐色細胞腫の 1 例 [Surgery without blood transfusion for pheocromocytoma in a Jehovah's Witness patient: a case report.] [Japanese]
Pancreas and liver resection in Jehovah's Witness patients: feasible and safe.
Pancreaticoduodenectomy after neoadjuvant therapy in a Jehovah's Witness with locally advanced pancreatic cancer: case report and approach to avoid transfusion.
The treatment of acute lymphoblastic leukemia in Jehovah's Witnesses and patients who cannot accept blood products.
Transplante autólogo de células-tronco hematopoiéticas sem uso de hemocomponentes. [Autologous hematopoietic stem cell transplantation without the use of blood transfusions.] [Portuguese, English abstract]
貧血の管理
Management of anaemia and iron deficiency in patients with cancer: ESMO clinical practice guidelines.
Intravenous iron in oncology.
High-dose (40,000 IU twice/week) alpha recombinant human erythropoietin as single agent in low/intermediate risk myelodysplastic syndromes: a retrospective investigation on 133 patients treated in a single institution.
Recombinant human erythropoietin is associated with increased overall survival in patients with multiple myeloma.
Darbepoetin-alfa and intravenous iron administration after autologous hematopoietic stem cell transplantation: a prospective multicenter randomized trial.
Randomized phase III trial of sequential adjuvant chemoradiotherapy with or without erythropoietin alfa in patients with high-risk cervical cancer: results of the NOGGO-AGO intergroup study.
Intravenous iron supplementation for the treatment of chemotherapy-induced anemia: a systematic review and meta-analysis of randomized controlled trials.
Epoetin alpha decreases the number of erythrocyte transfusions in patients with acute lymphoblastic leukemia, lymphoblastic lymphoma, and Burkitt leukemia/lymphoma: results of a randomized clinical trial.
Management of anemia in cancer patients.
Ferric carboxymaltose reduces transfusions and hospital stay in patients with colon cancer and anemia.
Leczenie ostrej białaczki u Świadków Jehowy—opis przypadku i przegląd piśmiennictwa. [Treatment of acute leukemia in Jehovah's Witnesses—a case report and review of the literature.] [Polish, English abstract]
Hemoglobin level at initiation of darbepoetin alfa: impact on need for transfusion and associated costs in chemotherapy-induced anemia treatment in Europe.
The short-term use of erythropoetin-stimulating agents: impact on the biochemical recurrence of prostate cancer.
Epoetin alfa in patients with advanced-stage Hodgkin's lymphoma: results of the randomized placebo-controlled GHSG HD15EPO trial.
Autologous stem-cell transplantation without hematopoietic support for the treatment of hematologic malignancies in Jehovah's Witnesses.
Randomised, phase III trial of epoetin-β to treat chemotherapy-induced anaemia according to the EU regulation.
Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome.
How I treat cancer-associated anemia.
Total dose iron dextran infusion in cancer patients: is it SaFe2+?
Update on safety of ESAs in cancer-induced anemia.
Thrombocytosis and venous thromboembolism in cancer patients with chemotherapy induced anemia may be related to ESA induced iron restricted erythropoiesis and reversed by administration of IV iron.
Iron or vitamin B12 deficiency in anemic cancer patients prior to erythropoiesis-stimulating agent therapy.
A randomized controlled trial comparing darbepoetin alfa doses in red blood cell transfusion-dependent patients with low- or intermediate-1 risk myelodysplastic syndromes.
The role of iron in the management of chemotherapy-induced anemia in cancer patients receiving erythropoiesis-stimulating agents.
Prospective study of erythropoietin use on quality of life and cost effectiveness in acute myeloid leukemia and allogeneic hematopoietic stem cell transplantation patients.
Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer: randomized clinical trial.
Perioperative anemia management in colorectal cancer patients: a pragmatic approach.
Meta-analysis of epoetin beta and darbepoetin alfa treatment for chemotherapy-induced anemia and mortality: Individual patient data from Japanese randomized, placebo-controlled trials.
Peri-operative blood management of Jehovah's Witnesses undergoing cytoreductive surgery for advanced ovarian cancer.
Clinical effectiveness and safety of erythropoietin-stimulating agents for the treatment of low- and intermediate-1-risk myelodysplastic syndrome: a systematic literature review.
Outcomes of erythropoiesis-stimulating agents in cancer patients with chemotherapy-induced anemia.
Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alpha.
High-dose chemotherapy without transfusion for Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in two Jehovah's Witnesses patients: a feasible option in the age of hematopoietic growth factors.
Addition of iron to erythropoiesis-stimulating agents in cancer patients: a meta-analysis of randomized trials.
Epoetin alfa improves anemia and anemia-related, patient-reported outcomes in patients with breast cancer receiving myelotoxic chemotherapy: results of a European, multicenter, randomized, controlled trial.
Clinical experience with ferric carboxymaltose in the treatment of cancer- and chemotherapy-associated anaemia.
Benefits and risks of using erythropoiesis-stimulating agents (ESAs) in lung cancer patients: study-level and patient-level meta-analyses.
Response to erythropoietic-stimulating agents in patients with chronic myelomonocytic leukemia.
赤血球造血刺激因子製剤
鉄静注
血小板減少症の治療管理
Autologous stem cell transplantation in patients who object to a blood transfusion: contribution of new pharmacological haematopoiesis support.
A multicenter study of romiplostim for chemotherapy-induced thrombocytopenia in solid tumors and hematologic malignancies.
The effect of interleukin 11 on thrombocytopenia associated with tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia.
Romiplostim efficacy in an acute myeloid leukemia patient with transfusion refractory thrombocytopenia.
The role of interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with solid tumors, lymphoma, acute myeloid leukemia and bone marrow failure syndromes.
Results of a phase I dose escalation study of eltrombopag in patients with advanced soft tissue sarcoma receiving doxorubicin and ifosfamide.
Efficacy of romiplostim in the treatment of chemotherapy induced thrombocytopenia (CIT) in a patient with mantle cell lymphoma.
Eltrombopag for radiation-induced thrombocytopenia in a glioblastoma patient.
Recombinant human interleukin 11 and bacterial infection in patients with haematological malignant disease undergoing chemotherapy: a double-blind placebo-controlled randomised trial.
Autologous stem-cell transplantation without hematopoietic support for the treatment of hematologic malignancies in Jehovah's Witnesses.
Effect of avatrombopag in the management of severe and refractory chemotherapy-induced thrombocytopenia (CIT) in patients with solid tumors.
Results of a randomized, double-blind study of romiplostim versus placebo in patients with low/intermediate-1-risk myelodysplastic syndrome and thrombocytopenia.
A randomized controlled trial of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving decitabine.
Thrombopoietin-receptor agonists in haematological disorders: the Danish experience.
Recombinant human thrombopoietin promotes platelet engraftment after haploidentical hematopoietic stem cell transplantation: a prospective randomized controlled trial.
The non-peptide thrombopoietin receptor agonist eltrombopag stimulates megakaryopoiesis in bone marrow cells from patients with relapsed multiple myeloma.
Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia.
The use of simple patient blood management strategies as an alternative to platelet and red cell transfusion in autologous stem cell transplant.
The effect of recombinant human erythropoietin on platelet counts is strongly modulated by the adequacy of iron supply.
A single center experience with romiplostim for the management of chemotherapy-induced thrombocytopenia.
Pharmacological therapies to minimise platelet transfusion.
Romiplostim for management of chemotherapy-induced thrombocytopenia.
Eltrombopag for the treatment of thrombocytopenia in patients with malignant and non-malignant hematologic disorders.
High-dose chemotherapy without transfusion for Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in two Jehovah's Witnesses patients: a feasible option in the age of hematopoietic growth factors.
Safety and tolerability of eltrombopag versus placebo for treatment of thrombocytopenia in patients with advanced myelodysplastic syndromes or acute myeloid leukaemia: a multicentre, randomised, placebo-controlled, double-blind, phase 1/2 trial.
Romiplostim for delayed platelet recovery and secondary thrombocytopenia following allogeneic stem cell transplantation.
Safety and efficacy of eltrombopag in post-hematopoietic stem cell transplantation (HSCT) thrombocytopenia.
Identifying drugs that cause acute thrombocytopenia: an analysis using 3 distinct methods.
Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation.
Subcutaneous or intravenous administration of romiplostim in thrombocytopenic patients with lower risk myelodysplastic syndromes.
Romiplostim treatment of chemotherapy-induced thrombocytopenia.
Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans.
A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine.
Eltrombopag for treatment of thrombocytopenia after allogeneic hematopoietic cell transplantation.
Low-dose interleukin-11 in patients with bone marrow failure: update of the M. D. Anderson Cancer Center experience.
A randomized, double-blind, placebo-controlled phase 2 study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate-1 risk myelodysplastic syndrome receiving lenalidomide.
Romiplostim for chemotherapy-induced thrombocytopenia: efficacy and safety of extended use.
Effect of the nonpeptide thrombopoietin receptor agonist eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome.
血管造影による塞栓術または血管閉塞
Hypervascular lesion in the head of the pancreas. Preoperative angiography and selective embolization results in bloodless operation.
Transcutaneous arterial embolization to control massive tumor bleeding in head and neck cancer: 63 patients' experiences from a single medical center.
Preoperative and therapeutic embolization of extremities of bone and soft tissue tumors.
Optimal schedule of preoperative embolization for spinal metastasis surgery.
Case report: octreotide as an adjunct to embolisation in the management of recurrent bleeding upper gastrointestinal metastases from primary renal cell cancer.
Role of embolization in the treatment of renal masses.
Surgery without blood transfusion for giant paraganglioma in a Jehovah's Witness patient.
Embolization of hypervascular bone metastases reduces intraoperative blood loss: a case-control study.
Management of bleeding in patients with advanced cancer.
Preoperative embolization of hypervascular spinal tumors: current practice and center experience.
Is preoperative embolization a prerequisite for spinal metastases surgical management?
外科的血液温存法
Pancreaticoduodenectomy without homologous blood transfusion in an anemic Jehovah's Witness.
Blood loss in surgical oncology: neglected quality indicator?
Transfusion requirements in microsurgical reconstruction in maxillofacial surgery: ethical and legal problems of patients who are Jehovah's Witnesses.
The theory and practice of bloodless surgery.
止血の管理と最適化
Use of Novoseven for arsenic trioxide-induced bleeding in PML.
Epsilon aminocaproic acid prevents bleeding in severely thrombocytopenic patients with hematological malignancies.
Tranexamic acid for control of haemorrhage in acute promyelocytic leukaemia.
Tranexamic acid therapy in acute myeloid leukemia: possible reduction of platelet transfusions.
Control of bleeding caused by thrombocytopenia associated with hematologic malignancy: an audit of the clinical use of recombinant activated Factor VII.
Pilot study on the safety and efficacy of desmopressin for the treatment or prevention of bleeding in patients with hematologic malignancies.
Fibrinolytic inhibitors for cancer-associated bleeding problems.
The off-label use of recombinant FVIIa in the treatment of a patient with T-cell non-Hodgkin lymphoma who developed intra-abdominal and intra-pleural hemorrhages followed by high-dose methotreaxate therapy.
Autologous stem-cell transplantation without hematopoietic support for the treatment of hematologic malignancies in Jehovah's Witnesses.
The potential role of recombinant activated FVII in the management of critical hemato-oncological bleeding: a systematic review.
Anti-fibrinolytic therapy with aminocaproic acid for the control of bleeding in thrombocytopenic patients.
Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhage.
Desmopressin and other synthetic vasopressin analogues in cancer treatment.
Management of bleeding complications of hematologic malignancies.
Vitamin K deficiency in cancer patients referred to a hospital palliative care team with bleeding and the impact of vitamin K replacement on laboratory indicators of vitamin K status.
Use of recombinant activated factor VII in a Jehovah's Witness patient.
Epsilon aminocaproic acid reduces transfusion requirements in patients with thrombocytopenic hemorrhage.
Clinical experience with recombinant factor VIIa in patients with thrombocytopenia.
Aminocaproic acid use in hospitalized patients with hematological malignancy: a case series.
Successful treatment of severe gastrointestinal bleeding after chemotherapy in acute myeloblastic leukemia with recombinant activated factor VII: report on one case and review of other uses in acute leukemias.
Management of bleeding in patients with advanced cancer.
Tranexamic acid to treat life-threatening hemorrhage in prostate cancer associated disseminated intravascular coagulation with excessive fibrinolysis.
A controlled trial of tranexamic acid therapy for the reduction of bleeding during treatment of acute myeloid leukemia.
Recombinant factor VIIa for bleeding in refractory thrombocytopenia.
Acute promyelocytic leukaemia and acquired alpha-2-plasmin inhibitor deficiency: a retrospective look at the use of epsilon-aminocaproic acid (Amicar) in 30 patients.
Effective treatment of life-threatening bleeding with recombinant activated factor VII in a patient with acute promyelocytic leukaemia.
抗線溶薬
遺伝子組換え活性型血液凝固第Ⅶ因子製剤(rFVIIa)
濃縮凝固因子製剤
デスモプレシン
術中の自己血管理
Safety of intraoperative blood salvage during liver transplantation in patients with hepatocellular carcinoma: A systematic review and meta-analysis.
Effect of autotransfusion system on tumor recurrence and survival in hepatocellular carcinoma patients.
Does autologous blood transfusion during liver transplantation for hepatocellular carcinoma increase risk of recurrence?
Phase II comparison study of intraoperative autotransfusion for major oncologic procedures.
Cerebral effect of acute normovolemic hemodilution during brain tumor resection.
Oncologic outcomes following radical prostatectomy with intraoperative cell salvage.
Effects of standardized acute normovolemic hemodilution on intraoperative allogeneic blood transfusion in patients undergoing major maxillofacial surgery.
Safety of the use of blood salvage and autotransfusion during liver transplantation for hepatocellular carcinoma.
A prospective randomized trial of acute normovolemic hemodilution compared to standard intraoperative management in patients undergoing major hepatic resection.
Impact of autologous blood transfusion on survival and recurrence among patients undergoing partial hepatectomy for colorectal cancer liver metastases.
Transfusion-free strategies in liver and pancreatic surgery: a predictive model of blood conservation for transfusion avoidance in mainstream populations.
Use of intraoperative cell-salvage for autologous blood transfusions in metastatic spine tumour surgery: a systematic review.
Metastatic efficiency of tumour cells can be impaired by intraoperative cell salvage process: truth or conjecture?
Acute normovolemic hemodilution in a Jehovah's Witness patient: a case report.
Pancreaticoduodenectomy after neoadjuvant therapy in a Jehovah's Witness with locally advanced pancreatic cancer: case report and approach to avoid transfusion.
Effectiveness of acute normovolemic hemodilution to minimize allogeneic blood transfusion in major liver resections.
The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer.
悪性腫瘍手術における術中回収式自己血輸血[Intraoperative, salvaged, autologous blood transfusion in oncologic surgery.] [Japanese]
Intraoperative cell salvage during radical cystectomy does not affect long-term survival.
Intraoperative cell salvage in radical prostatectomy does not appear to increase long-term biochemical recurrence, metastases, or mortality.
Should intraoperative cell-salvaged blood be used in patients with suspected or known malignancy?
Blood salvage and cancer surgery: a meta-analysis of available studies.
血液回収法
急性等容量性血液希釈
好中球減少症の治療管理
2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours.
Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 Update by the Infectious Diseases Society of America.
High-dose chemotherapy without transfusion for Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in two Jehovah's Witnesses patients: a feasible option in the age of hematopoietic growth factors.
Recommendations for the use of WBC growth factors: American Society of Clinical Oncology Clinical Practice Guideline Update.
輸血代替療法を用いた集中治療
Acute leukaemia in Jehovah's Witnesses.
Leczenie ostrej białaczki u Świadków Jehowy—opis przypadku i przegląd piśmiennictwa. [Treatment of acute leukemia in Jehovah's Witnesses—a case report and review of the literature.] [Polish, English abstract]
Treatment of acute leukaemia in adult Jehovah's Witnesses.
Autologous stem-cell transplantation without hematopoietic support for the treatment of hematologic malignancies in Jehovah's Witnesses.
Should Jehovah's Witnesses be denied intensive chemotherapy for acute leukemia?
Myeloablative therapy and bone marrow transplantation in Jehovah's Witnesses with malignancies: single center experience.
Developing a blood conservation care plan for Jehovah's Witness patients with malignant disease.
High-dose chemotherapy without transfusion for Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in two Jehovah's Witnesses patients: a feasible option in the age of hematopoietic growth factors.
Bloodless chimeric antigen receptor (CAR) T-cell therapy in Jehovah's Witnesses.
個別化または変法化学療法
Combined lenalidomide, low-dose dexamethasone, and rituximab achieves durable responses in rituximab-resistant indolent and mantle cell lymphomas.
Autologous stem-cell transplantation can be performed safely without the use of blood-product support.
Leucemia aguda en los Testigos de Jehová. [Acute leukemia in Jehovah's Witnesses.] [Spanish]
The use of blood conservation methods in addition to erythropoietin allows myeloablative allogeneic stem cell transplantation without the use of blood products.
Oral azacitidine (CC-486) for the treatment of myelodysplastic syndromes and acute myeloid leukemia.
Hematologic improvement and response in elderly AML/RAEB patients treated with valproic acid and low-dose Ara-C.
Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy.
Low-dose cytosine arabinoside as an alternative treatment for acute leukemia in Jehovah's Witnesses.
Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): a randomised phase 3 trial.
Azacitidine and venetoclax in previously untreated acute myeloid leukemia.
Treatment of acute leukaemia in adult Jehovah's Witnesses.
Minimally-myelosuppressive asparaginase-containing induction regimen for treatment of a Jehovah's Witness with mutant IDH1/NPM1/NRAS acute myeloid leukemia.
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.
Successful treatment of a Jehovah's Witness with acute promyelocytic leukemia.
Induction with azacytidine followed by allogeneic hematopoietic stem cell transplantation in a Jehovah's Witness with acute monocytic leukemia.
Immediate or delayed therapy with 2-CdA for hairy cell leukemia in Jehova's Witness?
Tailored therapy of adult acute leukaemia in Jehovah's Witnesses: unjustified reluctance to treat.
Successful treatment of acute promyelocytic leukemia in a pregnant Jehovah's Witness with all-trans retinoic acid, rhG-CSF, and erythropoietin.
Long-term efficacy of low-dose all-trans retinoic acid plus minimal chemotherapy induction followed by the addition of intravenous arsenic trioxide post-remission therapy in newly diagnosed acute promyelocytic leukaemia.
Cytarabine dose for acute myeloid leukemia.
Myeloablative therapy and bone marrow transplantation in Jehovah's Witnesses with malignancies: single center experience.
Ivosidenib and azacitidine in IDH1-mutated acute myeloid leukemia.
Effect of chemotherapy delays and dose reductions on progression free and overall survival in the treatment of epithelial ovarian cancer.
The treatment of acute lymphoblastic leukemia in Jehovah's Witnesses and patients who cannot accept blood products.
Developing a blood conservation care plan for Jehovah's Witness patients with malignant disease.
High-dose chemotherapy without transfusion for Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in two Jehovah's Witnesses patients: a feasible option in the age of hematopoietic growth factors.
Hematopoietic growth factors: personalization of risks and benefits.
Bloodless chimeric antigen receptor (CAR) T-cell therapy in Jehovah's Witnesses.
Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
Bloodless (transfusion-free) hematopoietic stem cell transplants: the Mexican experience.
A Mexican way to cope with stem cell grafting.
Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet.
SCT in Jehovah's Witnesses: the bloodless transplant.
Treatment of acute myelogenous leukemia with outpatient azacitidine.
Isolated limb perfusion for an irresectable melanoma recurrence in a Jehovah's Witness.
Management of cytopenias in patients with myelofibrosis treated with ruxolitinib and effect of dose modifications on efficacy outcomes.
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme.
Venetoclax plus LDAC for newly diagnosed AML ineligible for intensive chemotherapy: a phase 3 randomized placebo-controlled trial.
Decreased transfusion requirements for patients receiving nonmyeloablative compared with conventional peripheral blood stem cell transplants from HLA-identical siblings.
A Jehovah's Witness with acute myeloid leukemia successfully treated with an epigenetic drug, azacitidine: a clue for development of anti-AML therapy requiring minimum blood transfusions.
Acute lymphoblastic leukaemia in a Jehovah's Witness: a management dilemma.
Oral tetra-arsenic tetra-sulfide formula versus intravenous arsenic trioxide as first-line treatment of acute promyelocytic leukemia: a multicenter randomized controlled trial.
無輸血での造血幹細胞移植
Autologous stem cell transplantation in patients who object to a blood transfusion: contribution of new pharmacological haematopoiesis support.
Autologous stem-cell transplantation can be performed safely without the use of blood-product support.
Safety of bloodless autologous stem cell transplantation in Jehovah's Witness patients.
The use of blood conservation methods in addition to erythropoietin allows myeloablative allogeneic stem cell transplantation without the use of blood products.
Hematopoietic stem cell transplantation without the use of blood components by the patient's choice: experience of 2 Brazilian centers.
Transfusion challenges in hematology oncology and hematopoietic stem cell transplant - literature review and local experience.
Autologous stem-cell transplantation without hematopoietic support for the treatment of hematologic malignancies in Jehovah's Witnesses.
Myeloablative chemotherapy and autologous stem cell transplantation without the use of blood products.
Safety and survival outcomes for bloodless transplantation in patients with myeloma.
Bloodless tandem autologous transplant in Jehovah's Witness patients.
Myeloablative therapy and bone marrow transplantation in Jehovah's Witnesses with malignancies: single center experience.
Bloodless (transfusion-free) hematopoietic stem cell transplants: the Mexican experience.
SCT in Jehovah's Witnesses: the bloodless transplant.
医原性貧血を避けるための採血量の制限
Phlebotomy—a minimalist approach.
Savoring every drop—vampire or mosquito?
Hospital-acquired anemia: prevalence, outcomes, and healthcare implications.
Twenty-five million liters of blood into the sewer.
Reduction of blood loss from laboratory testing in hospitalized adult patients using small-volume (pediatric) tubes.
Iatrogenic anemia (can it be prevented?).
診断目的以外の失血の抑制
Stress ulcer prophylaxis.
Management of menorrhagia associated with chemotherapy-induced thrombocytopenia in women with hematologic malignancy.
Stress-related mucosal bleeding in critically ill oncology patients.
Menstrual suppression in special circumstances.
Prevention of severe menorrhagia in oncology patients with treatment-induced thrombocytopenia by luteinizing hormone-releasing hormone agonist and depo-medroxyprogesterone acetate.
Management of uterine bleeding during hematopoietic stem cell transplantation.
等容量性貧血の許容
Compliance rates and outcomes associated with a restrictive transfusion policy in gynecologic oncology patients.
Liberal or restrictive transfusion in high-risk patients after hip surgery.
Long-lasting extreme anemia during the therapy of acute lymphoblastic leukemia in a Jehovah's Witness patient.
Autologous stem-cell transplantation without hematopoietic support for the treatment of hematologic malignancies in Jehovah's Witnesses.
Do basic laboratory tests or clinical observations predict bleeding in thrombocytopenic oncology patients? A reevaluation of prophylactic platelet transfusions.
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.
Red blood cell transfusion in non-bleeding critically ill patients with moderate anemia: is there a benefit?
How low should we go: A systematic review and meta-analysis of the impact of restrictive red blood cell transfusion strategies in oncology.
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
Liberal versus restrictive red blood cell transfusion thresholds in hematopoietic cell transplantation: a randomized, open label, phase III, noninferiority trial.
Transfusion indications for patients with cancer.
Restrictive blood transfusion protocol in malignant upper gastrointestinal and pancreatic resections patients reduces blood transfusions with no increase in patient morbidity.
大量出血の有害作用
Association between perioperative blood transfusions and clinical outcomes in patients undergoing bladder cancer surgery: a systematic review and meta-analysis study.
Impact of intraoperative blood loss on long-term survival after lung cancer resection.
Acute bleeding after bone marrow transplantation (BMT)—incidence and effect on survival. A quantitative analysis in 1,402 patients.
Financial and clinical outcomes associated with surgical bleeding complications.
Elective surgery without transfusion: influence of preoperative hemoglobin level and blood loss on mortality.
輸血のリスクと不確実性
Effects of allogeneic red blood cell transfusions on clinical outcomes in patients undergoing colorectal cancer surgery: a systematic review and meta-analysis.
Blood transfusion and cancer surgery outcomes: a continued reason for concern.
Perioperative blood transfusions promote pancreas cancer progression.
Impact of allogeneic and autologous transfusion on immune function in patients with tumors.
A cohort investigation of anaemia, treatment and the use of allogeneic blood transfusion in colorectal cancer surgery.
Blood transfusions, thrombosis, and mortality in hospitalized patients with cancer.
Perioperative blood transfusion, age at surgery, and prognosis in a database of 526 upper gastrointestinal cancers.
Perioperative allogenenic blood transfusion is associated with worse clinical outcome for patients undergoing gastric carcinoma surgery: a meta-analysis.
Perioperative allogenenic blood transfusion is associated with worse clinical outcomes for hepatocellular carcinoma: a meta-analysis.
Correlations between neoadjuvant treatment, anemia, and perioperative complications in patients undergoing esophagectomy for cancer.
How low should we go: A systematic review and meta-analysis of the impact of restrictive red blood cell transfusion strategies in oncology.
Impact of perioperative allogeneic red blood cell transfusion on recurrence and overall survival after resection of colorectal liver metastases.
Current perspectives in transfusion-transmitted infectious diseases: emerging and re-emerging infections.
臨床成績
Liberal versus restrictive red blood cell transfusion thresholds in hematopoietic cell transplantation: a randomized, open label, phase III, noninferiority trial.
経済効果
Impact of a patient blood management monitoring and feedback programme on allogeneic blood transfusions and related costs.
術前の患者の評価と輸血リスクの評価
Transfusion and coagulation management in liver transplantation.
The beneficial effects of minimizing blood loss in pancreatoduodenectomy.
術前の計画と患者の状態の最適化
Short-term preoperative diet decreases bleeding after partial hepatectomy: results from a multi-institutional randomized controlled trial.
Recommendations from the international consensus conference on anemia management in surgical patients (ICCAMS).
集学的,職種横断的な,個別化されたアプローチ
Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis.
Liver transplantation in a Jehovah's Witness with ankylosing spondylitis.
Liver transplantation in Jehovah's Witnesses: 13 consecutive cases at a single institution.
Pancreatic resections in patients who refuse blood transfusions. The application of a perioperative protocol for a true bloodless surgery.
Patient blood management: a patient-orientated approach to blood replacement with the goal of reducing anemia, blood loss and the need for blood transfusion in elective surgery.
Bloodless surgery in geriatric surgery.
Transfusion-free strategies in liver and pancreatic surgery: a predictive model of blood conservation for transfusion avoidance in mainstream populations.
The theory and practice of bloodless surgery.
Obiettivi di un programma di chirurgia senza sangue. Studio comparativo (chirurgia maggiore vs chirurgia minore-media) su 51 pazienti testimoni di Geova. [Objectives of a bloodless surgery program. A comparative study (major surgery vs. minor-medium surgery) in 51 Jehovah's Witnesses patients.] [Italian, English abstract]
Strategies to minimize intraoperative blood loss during major surgery.
Blood-management programs: a clinical and administrative model with program implementation strategies.
術前貧血管理と赤血球数の最適化
The role of intravenous iron in anemia management and transfusion avoidance.
Impact of preoperative erythropoietin on allogeneic blood transfusions in surgical patients: results from a systematic review and meta-analysis.
Liver transplantation in Jehovah's Witnesses: 13 consecutive cases at a single institution.
The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Efficacy and safety of erythropoietin and intravenous iron in perioperative blood management: a systematic review.
Recommendations from the international consensus conference on anemia management in surgical patients (ICCAMS).
Blood conservation in pediatric anesthesia.
血小板減少症の治療管理
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia.
Preoperative use of romiplostim in thrombocytopenic patients with chronic hepatitis C and liver cirrhosis.
抗凝固療法の管理と中和
Emergency reversal of anticoagulation: from theory to real use of prothrombin complex concentrates. A retrospective Italian experience.
Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.
Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study.
Emergency reversal of warfarin anticoagulation.
Recent advances in the development of specific antidotes for target-specific oral anticoagulants.
Idarucizumab for dabigatran reversal - full cohort analysis.
Oral anticoagulation in surgical procedures: risks and recommendations.
外科的血液温存法
The theory and practice of bloodless surgery.
止血の管理と最適化
Fibrinogen replacement therapy: a critical review of the literature.
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss.
Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology.
Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy.
Recombinant factor VIIa as last-resort treatment of desperate haemorrhage.
Consensus recommendations for the off-label use of recombinant human factor VIIa (NovoSeven(R)) therapy.
Association of intravenous tranexamic acid with thromboembolic events and mortality: a systematic review, meta-analysis, and meta-regression.
抗線溶薬
遺伝子組換え活性型血液凝固第Ⅶ因子製剤(rFVIIa)
濃縮凝固因子製剤
外科的出血か凝固異常による出血かを同定するための血液粘弾性試験
体温管理(低体温の回避)
Consequences of inadvertent perioperative hypothermia.
Comparison of resistive heating and forced-air warming to prevent inadvertent perioperative hypothermia.
Effectiveness of strategies for the management and/or prevention of hypothermia within the adult perioperative environment.
The effects of mild perioperative hypothermia on blood loss and transfusion requirement.
A systematic review of intraoperative warming to prevent postoperative complications.
Intraoperative core temperature patterns, transfusion requirement, and hospital duration in patients warmed with forced air.
Randomized clinical trial of perioperative systemic warming in major elective abdominal surgery.
注意深い輸液・体液管理
Perioperative fluid management strategies in major surgery: a stratified meta-analysis.
Major hepatectomy in children: approaching blood transfusion-free.
Restrictive strategy of intraoperative fluid maintenance during optimization of oxygen delivery decreases major complications after high-risk surgery.
Choice of fluid in acute illness: what should be given? An international consensus.
Impact of goal-directed perioperative fluid management in high-risk surgical procedures: a literature review.
Safety of modern starches used during surgery.
術中の自己血管理
Does autologous blood transfusion during liver transplantation for hepatocellular carcinoma increase risk of recurrence?
Cell salvage as part of a blood conservation strategy in anaesthesia.
Phase II comparison study of intraoperative autotransfusion for major oncologic procedures.
Very low rate of patient-related adverse events associated with the use of intraoperative cell salvage.
Intra-operative cell salvage: a fresh look at the indications and contraindications.
Safety of the use of blood salvage and autotransfusion during liver transplantation for hepatocellular carcinoma.
A case of thoracic esophageal cancer undergone esophagectomy after induction chemotherapy in a Jehovah's Witness.
A prospective randomized trial of acute normovolemic hemodilution compared to standard intraoperative management in patients undergoing major hepatic resection.
Association of Anaesthetists guidelines: cell salvage for peri-operative blood conservation 2018.
Transfusion-free strategies in liver and pancreatic surgery: a predictive model of blood conservation for transfusion avoidance in mainstream populations.
Use of intraoperative cell-salvage for autologous blood transfusions in metastatic spine tumour surgery: a systematic review.
Metastatic efficiency of tumour cells can be impaired by intraoperative cell salvage process: truth or conjecture?
A prospective randomized study comparing two techniques of perioperative blood conservation: isovolemic hemodilution and hypervolemic hemodilution.
Blood transfusion risks and alternative strategies in pediatric patients.
Acute normovolemic hemodilution.
Is cell salvage safe in liver resection? A pilot study.
Acute normovolemic hemodilution.
Should intraoperative cell-salvaged blood be used in patients with suspected or known malignancy?
Blood salvage and cancer surgery: a meta-analysis of available studies.
血液回収法
急性等容量性血液希釈
麻酔学的血液温存法
Controlled hypotension: a guide to drug choice.
Influence of controlled hypotension versus normotension on amount of blood loss during breast reduction.
Does neuraxial anesthesia reduce intraoperative blood loss? A meta-analysis.
Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials.
低血圧法
局所麻酔
医原性貧血を避けるための採血量の制限
Savoring every drop—vampire or mosquito?
Surgical vampires and rising health care expenditure: reducing the cost of daily phlebotomy.
術後貧血の管理
Recombinant human erythropoietin therapy in critically ill Jehovah's Witnesses.
Severe acute anemia after liver transplantation in an elderly Jehovah's Witness treated with high-dose erythropoietin and ferric carboxymaltose: a case report.
Intravenous ferric carboxymaltose versus standard care in the management of postoperative anaemia: a prospective, open-label, randomised controlled trial.
How do we treat life-threatening anemia in a Jehovah's Witness patient?
Transfusion-free management of gastrointestinal bleeding: the experience of a Bloodless Institute.
患者の貧血に対する許容力の最適化
The influence of volume management on outcome.
Prophylactic hypothermia and neuromuscular blockade to limit myocardial oxygen demand in a critically anemic Jehovah's Witness after emergency surgery.
Pillar III—optimisation of anaemia tolerance.
等容量性貧血の許容
Patient blood management: a patient-orientated approach to blood replacement with the goal of reducing anemia, blood loss and the need for blood transfusion in elective surgery.
Restrictive blood transfusion practices are associated with improved patient outcomes.
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.
Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis.
Anemia and perioperative red blood cell transfusion: a matter of tolerance.
Pillar III—optimisation of anaemia tolerance.
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review.
大量出血の有害作用
The beneficial effects of minimizing blood loss in pancreatoduodenectomy.
輸血のリスクと不確実性
Blood transfusion and cancer surgery outcomes: a continued reason for concern.
Surgical outcomes and transfusion of minimal amounts of blood in the operating room.
Adverse blood transfusion outcomes: establishing causation.
Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature.
Survival rate changes with transfusion of blood products during liver transplantation.
臨床成績
Peri-operative blood transfusion increases length of hospital stay and number of postoperative complications in non-cardiac surgical patients.
Association between the use of blood components and the five-year mortality after liver transplant. [Associação entre Uso de Hemocomponentes e Mortalidade em Cinco Anos após Transplante Hepático.] [English, Portuguese]
Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Association between intraoperative blood transfusion and mortality and morbidity in patients undergoing noncardiac surgery.
Restrictive blood transfusion practices are associated with improved patient outcomes.
Intraoperative cardiac arrests in adults undergoing noncardiac surgery: incidence, risk factors, and survival outcome.
Review article: Risks of anemia and related management strategies: can perioperative blood management improve patient safety?
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review.
Blood-management programs: a clinical and administrative model with program implementation strategies.
Implementation of a comprehensive patient blood management program for hospitalized patients at a large united states medical center.
Safety and efficacy of methods for reducing perioperative allogeneic transfusion: a critical review of the literature.
経済効果
Cost-effectiveness of cell salvage and alternative methods of minimising perioperative allogeneic blood transfusion: a systematic review and economic model.
Estimating the epidemiological and economic impact of implementing preoperative anaemia measures in the German healthcare system: the health economic footprint of patient blood management.
Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
Economic considerations on transfusion medicine and patient blood management.
From blood transfusion to patient blood management: a new paradigm for patient care and cost assessment of blood transfusion practice.
Safety, cost savings, simplicity back broader use of bloodless surgery.
Associations between preoperative anaemia and hospital costs following major abdominal surgery: cohort study.
A prospective study investigating the cost effectiveness of intraoperative blood salvage during liver transplantation.
Effective reduction of blood product use in a community teaching hospital: when less is more.
Prospective monitoring of plasma and platelet transfusions in a large teaching hospital results in significant cost reduction.
Activity-based costs of blood transfusions in surgical patients at four hospitals.
Intra-operative cell salvage in South Africa: feasible, beneficial and economical.
Randomized trial comparing packed red cell blood transfusion with and without leukocyte depletion for gastrointestinal surgery.
Implementation of a comprehensive patient blood management program for hospitalized patients at a large united states medical center.
The volume of returned red blood cells in a large blood salvage program: where does it all go?
An economic analysis of costs associated with development of a cell salvage program.
術前の計画と患者の状態の最適化
Preparing a Jehovah's Witness for major elective surgery.
Preoperative evaluation of the adult patient undergoing non-cardiac surgery: guidelines from the European Society of Anaesthesiology.
Avoiding blood transfusion in surgical patients (including Jehovah's Witnesses).
Patient blood management is key before elective surgery.
Bloodless medicine: clinical care without allogeneic blood transfusion.
Blood transfusion and orthognathic surgery--a thing of the past?
The effect of preoperative recombinant erythropoietin on postoperative hematocrit level after orthognathic surgery.
集学的,職種横断的な,個別化されたアプローチ
No increased bleeding risk for oral surgery in patients with severe congenital bleeding disorders due to intense perioperative management.
Case report: The management of advanced oral cancer in a Jehovah's Witness using the Ultracision Harmonic Scalpel.
Blood transfusion and orthognathic surgery--a thing of the past?
The use of erythropoietin in a patient having major oral and maxillofacial surgery and refusing blood transfusion.
Multimodal strategy for reduction of homologous transfusions in cranio-maxillofacial surgery.
Treatment of individuals who cannot receive blood products for religious or other reasons.
抗凝固療法の管理と中和
Risk of bleeding after dentoalveolar surgery in patients taking anticoagulants.
Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents.
Emergency reversal of warfarin anticoagulation.
Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers.
Reversal of clopidogrel-induced bleeding with rFVIIa in healthy subjects: a randomized, placebo-controlled, double-blind, exploratory study.
血管造影による塞栓術または血管閉塞
Transarterial embolization of the external carotid artery in the treatment of life-threatening haemorrhage following blunt maxillofacial trauma.
Transarterial embolization in the management of life-threatening hemorrhage after maxillofacial trauma: a case report and review of literature.
Endovascular preoperative embolization for temporomandibular joint replacement surgery.
止血の管理と最適化
The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial.
The effect of nasal application of cocaine/adrenaline on blood loss in Le Fort I osteotomies.
Effect of tranexamic acid irrigation on perioperative blood loss during orthognathic surgery: a double-blind, randomized controlled clinical trial.
Clinical applications of fibrin sealants.
Surgical removal of intra- and extraoral cavernous lymphangiomas using intraoperative-assisted intralesional fibrin glue injections.
Hemostasis of oral surgery wounds with the HemCon Dental Dressing.
The efficacy and safety of tranexamic acid in cranio-maxillofacial and plastic surgery.
Prevention of bleeding in orthognathic surgery--a systematic review and meta-analysis of randomized controlled trials.
Evaluation of the efficacy of tranexamic acid on blood loss in orthognathic surgery. A prospective, randomized clinical study.
Tranexamic acid is associated with improved operative field in orthognathic surgery.
Effectiveness of intravenous haemocoagulase on haemorrhage control in bi-maxillary orthognathic surgery-a prospective, randomised, controlled, double-blind study.
The role of antifibrinolytics in reducing blood loss during craniofacial or orthognathic surgical procedures: a meta-analysis.
Aprotinin reduces blood loss and the need for transfusion in orthognathic surgery.
Topical hemostatic agents: what the oral and maxillofacial surgeon needs to know.
Evaluation of hemorrhage depressors on blood loss during orthognathic surgery: a retrospective study.
抗線溶薬
デスモプレシン
他の薬剤
局所止血剤
術中の自己血管理
Effects of standardized acute normovolemic hemodilution on intraoperative allogeneic blood transfusion in patients undergoing major maxillofacial surgery.
Intraoperative red cell salvage in head and neck surgery.
Acute perioperative normovolaemic haemodilution in major maxillofacial surgery.
血液回収法
急性等容量性血液希釈
麻酔学的血液温存法
Orthognathic surgery with or without induced hypotension.
Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study.
Effects of hypotensive anesthesia on reducing intraoperative blood loss, duration of operation, and quality of surgical field during orthognathic surgery: a systematic review and meta-analysis of randomized controlled trials.
Hypotensive anaesthesia and blood loss in orthognathic surgery: a clinical study.
Induced hypotensive anesthesia for adolescent orthognathic surgery patients.
Anesthetic considerations for orthognathic surgery with evaluation of difficult intubation and technique for hypotensive anesthesia.
High Le Fort I and bilateral split sagittal osteotomy in Crouzon syndrome.
Comparative evaluation of hypotensive and normotensive anesthesia on Lefort I osteotomies: a randomized, double-blind, prospective clinical study.
低血圧法
術後貧血の管理
Recombinant human erythropoietin in severe anaemia: issues of dosing and duration.
Intravenous ferric carboxymaltose versus standard care in the management of postoperative anaemia: a prospective, open-label, randomised controlled trial.
患者の貧血に対する許容力の最適化
Anemia and perioperative red blood cell transfusion: a matter of tolerance.
Recombinant human erythropoietin in the treatment of head and neck tumour anaemia.
Effect of transfusion guidelines on postoperative transfusion in children undergoing craniofacial reconstruction surgery.
臨床成績
Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis.
経済効果
Effects of standardized acute normovolemic hemodilution on intraoperative allogeneic blood transfusion in patients undergoing major maxillofacial surgery.
Patient blood management is associated with a substantial reduction of red blood cell utilization and safe for patient's outcome: a prospective, multicenter cohort study with a noninferiority design.
Acute perioperative normovolaemic haemodilution in major maxillofacial surgery.
Impact of bleeding-related complications and/or blood product transfusions on hospital costs in inpatient surgical patients.
術前の患者の評価と輸血リスクの評価
Perioperative analgesia and the effects of dietary supplements.
Herbal medicines and perioperative care.
Perioperative use of selective serotonin reuptake inhibitors and risks for adverse outcomes of surgery.
Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study.
Identifying, monitoring and reducing preventable major bleeds in the hospital setting.
Guidelines on the assessment of bleeding risk prior to surgery or invasive procedures. British Committee for Standards in Haematology.
Clinical herbal interactions with conventional drugs: from molecules to maladies.
Transfusion and coagulation management in liver transplantation.
Preoperative assessment of coagulation disorders.
Preparing a Jehovah's Witness for major elective surgery.
Aspirin in patients undergoing noncardiac surgery.
Antiplatelet drugs: a review of their pharmacology and management in the perioperative period.
Prediction of transfusion requirements in surgical patients: a review.
In the clinic. Preoperative evaluation.
Pre-operative haematological assessment in patients scheduled for major surgery.
Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study.
Preoperative assessment of the older patient: a narrative review.
The beneficial effects of minimizing blood loss in pancreatoduodenectomy.
Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery.
術前の計画と患者の状態の最適化
Short-term preoperative diet decreases bleeding after partial hepatectomy: results from a multi-institutional randomized controlled trial.
Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines.
Optimizing postoperative outcomes with efficient preoperative assessment and management.
Merits of exercise therapy before and after major surgery.
Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in patients having combined coronary artery bypass grafting and valve surgery.
Romiplostim in the management of the thrombocytopenic surgical patient.
Bloodless medicine: what to do when you can't transfuse.
Preparation of the patient for surgery.
Recommendations from the international consensus conference on anemia management in surgical patients (ICCAMS).
Essential role of patient blood management in a pandemic: a call for action.
集学的,職種横断的な,個別化されたアプローチ
Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis.
Liver transplantation in a Jehovah's Witness with ankylosing spondylitis.
Perioperative management of four anaemic female Jehovah's Witnesses undergoing urgent complex cardiac surgery.
Preparing a Jehovah's Witness for major elective surgery.
Liver transplantation in Jehovah's Witnesses: 13 consecutive cases at a single institution.
Pancreatic resections in patients who refuse blood transfusions. The application of a perioperative protocol for a true bloodless surgery.
Patient blood management: a patient-orientated approach to blood replacement with the goal of reducing anemia, blood loss and the need for blood transfusion in elective surgery.
Bloodless medicine: clinical care without allogeneic blood transfusion.
Bloodless surgery in geriatric surgery.
Perioperative management of patients for whom transfusion is not an option.
Anesthesia management of a Jehovah's Witness patient with pheochromocytoma undergoing off pump coronary artery bypass graft surgery—a case report.
Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle.
Blood conservation strategies in Jehovah's Witness patients undergoing complex aortic surgery: a report of three cases.
Aortic arch replacement and elephant trunk procedure: an interdisciplinary approach to surgical reconstruction, perfusion strategies and blood management.
Multidisciplinary management of a Jehovah's Witness patient for the removal of a renal cell carcinoma extending into the right atrium.
Update on blood conservation for cardiac surgery.
Anesthetic management for ascending aorta replacement in a patient who refused autologous transfusion for religious reasons.
Obiettivi di un programma di chirurgia senza sangue. Studio comparativo (chirurgia maggiore vs chirurgia minore-media) su 51 pazienti testimoni di Geova. [Objectives of a bloodless surgery program. A comparative study (major surgery vs. minor-medium surgery) in 51 Jehovah's Witnesses patients.] [Italian, English abstract]
Thoraco-abdominal aneurysm repair in a Jehovah's Witness: maximising blood conservation.
Programmatic blood conservation in cardiac surgery.
Allogeneic blood transfusion reduction by risk-based protocol in total joint arthroplasty.
Bloodless medicine: what to do when you can't transfuse.
Strategies to minimize intraoperative blood loss during major surgery.
Patient blood management in Europe.
2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines.
The pillars of patient blood management: key to successful implementation.
Blood-management programs: a clinical and administrative model with program implementation strategies.
A standardized multidisciplinary approach reduces the use of allogeneic blood products in patients undergoing cardiac surgery.
The perfusionist's role in a collaborative multidisciplinary approach to blood transfusion reduction in cardiac surgery.
Hypotensive anesthesia combined with tranexamic acid reduces perioperative blood loss in simultaneous bilateral total hip arthroplasty: a retrospective cohort study.
術前貧血管理と赤血球数の最適化
The role of intravenous iron in anemia management and transfusion avoidance.
The safety of intravenous iron preparations: systematic review and meta-analysis.
Impact of preoperative erythropoietin on allogeneic blood transfusions in surgical patients: results from a systematic review and meta-analysis.
Liver transplantation in Jehovah's Witnesses: 13 consecutive cases at a single institution.
The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines.
Treatment through a preoperative anemia clinic is associated with a reduction in perioperative red blood cell transfusion in patients undergoing orthopedic and gynecologic surgery.
Efficacy and safety of erythropoietin and intravenous iron in perioperative blood management: a systematic review.
International consensus statement on the peri-operative management of anaemia and iron deficiency.
'Fit to fly': overcoming barriers to preoperative haemoglobin optimization in surgical patients.
Effects of intravenous iron combined with low-dose recombinant human erythropoietin on transfusion requirements in iron-deficient patients undergoing bilateral total knee replacement arthroplasty.
Recommendations from the international consensus conference on anemia management in surgical patients (ICCAMS).
Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials.
Effect of single recombinant human erythropoietin injection on transfusion requirements in preoperatively anemic patients undergoing valvular heart surgery.
血小板減少症の治療管理
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia.
Romiplostim treatment allows for platelet transfusion-free liver transplantation in pediatric thrombocytopenic patient with primary sclerosing cholangitis.
Preoperative use of romiplostim in thrombocytopenic patients with chronic hepatitis C and liver cirrhosis.
Avatrombopag before procedures reduces need for platelet transfusion in patients with chronic liver disease and thrombocytopenia.
抗凝固療法の管理と中和
Emergency reversal of anticoagulation: from theory to real use of prothrombin complex concentrates. A retrospective Italian experience.
Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Pharmacological prophylaxis of bleeding in surgical patients treated with aspirin.
Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.
How I treat warfarin-associated coagulopathy in patients with intracerebral hemorrhage.
Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study.
Reversing the effects of antiplatelet agents in the setting of intracranial hemorrhage: a look at the literature.
Bleeding risk and reversal strategies for old and new anticoagulants and antiplatelet agents.
Emergency reversal of warfarin anticoagulation.
Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers.
Recent advances in the development of specific antidotes for target-specific oral anticoagulants.
Idarucizumab for dabigatran reversal - full cohort analysis.
Reversal of clopidogrel-induced bleeding with rFVIIa in healthy subjects: a randomized, placebo-controlled, double-blind, exploratory study.
Oral anticoagulation in surgical procedures: risks and recommendations.
Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding.
止血の管理と最適化
Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa?
The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage.
Prophylactic use of factor IX concentrate in a Jehovah's Witness patient.
Bloodless orthotopic heart transplantation in a Jehovah's Witness.
Alternatives to allogeneic platelet transfusion.
Tranexamic acid in patients undergoing noncardiac surgery.
Fibrinogen replacement therapy: a critical review of the literature.
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study.
Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry.
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin.
Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery.
Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study.
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss.
Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology.
Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy.
Recombinant factor VIIa as last-resort treatment of desperate haemorrhage.
Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial.
Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate.
Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate.
Consensus recommendations for the off-label use of recombinant human factor VIIa (NovoSeven(R)) therapy.
Association of intravenous tranexamic acid with thromboembolic events and mortality: a systematic review, meta-analysis, and meta-regression.
Oral is as effective as intravenous tranexamic acid at reducing blood loss in thoracolumbar spinal fusions: a prospective randomized trial.
抗線溶薬
遺伝子組換え活性型血液凝固第Ⅶ因子製剤(rFVIIa)
濃縮凝固因子製剤
デスモプレシン
外科的出血か凝固異常による出血かを同定するための血液粘弾性試験
体温管理(低体温の回避)
Influence of body core temperature on blood loss and transfusion requirements during off-pump coronary artery bypass grafting: A comparison of 3 warming systems.
Effectiveness of strategies for the management and/or prevention of hypothermia within the adult perioperative environment.
The effects of mild perioperative hypothermia on blood loss and transfusion requirement.
Mild hypothermia increases blood loss and transfusion requirements during total hip arthroplasty.
A systematic review of intraoperative warming to prevent postoperative complications.
Intraoperative core temperature patterns, transfusion requirement, and hospital duration in patients warmed with forced air.
Aggressive warming reduces blood loss during hip arthroplasty.
Randomized clinical trial of perioperative systemic warming in major elective abdominal surgery.
注意深い輸液・体液管理
Perioperative fluid management strategies in major surgery: a stratified meta-analysis.
How good patient blood management leads to excellent outcomes in Jehovah's Witness patients undergoing cardiac surgery.
Restrictive strategy of intraoperative fluid maintenance during optimization of oxygen delivery decreases major complications after high-risk surgery.
Choice of fluid in acute illness: what should be given? An international consensus.
Strategies to reduce the use of blood products: a European perspective.
Impact of goal-directed perioperative fluid management in high-risk surgical procedures: a literature review.
Safety of modern starches used during surgery.
Management of intraoperative fluid balance and blood conservation techniques in adult cardiac surgery.
術中の自己血管理
Safety of intraoperative blood salvage during liver transplantation in patients with hepatocellular carcinoma: A systematic review and meta-analysis.
Cell salvage in obstetrics.
Does autologous blood transfusion during liver transplantation for hepatocellular carcinoma increase risk of recurrence?
Cell salvage as part of a blood conservation strategy in anaesthesia.
Phase II comparison study of intraoperative autotransfusion for major oncologic procedures.
Autologous blood transfusion during emergency trauma operations.
Cell salvage for minimising perioperative allogeneic blood transfusion.
Cerebral effect of acute normovolemic hemodilution during brain tumor resection.
Very low rate of patient-related adverse events associated with the use of intraoperative cell salvage.
Intra-operative cell salvage: a fresh look at the indications and contraindications.
Role of intraoperative red cell salvage and autologus transfusion in metastatic spine surgery: a pilot study and review of literature.
Greater volume of acute normovolemic hemodilution may aid in reducing blood transfusions after cardiac surgery.
Oncologic outcomes following radical prostatectomy with intraoperative cell salvage.
The use of acute hemodilution in parturients undergoing cesarean section.
Safety of the use of blood salvage and autotransfusion during liver transplantation for hepatocellular carcinoma.
A case of thoracic esophageal cancer undergone esophagectomy after induction chemotherapy in a Jehovah's Witness.
A prospective randomized trial of acute normovolemic hemodilution compared to standard intraoperative management in patients undergoing major hepatic resection.
Acute normovolemic hemodilution and nitroglycerin-induced hypotension: comparative effects on tissue oxygenation and allogeneic blood transfusion requirement in total hip arthroplasty.
Association of Anaesthetists guidelines: cell salvage for peri-operative blood conservation 2018.
Transfusion-free strategies in liver and pancreatic surgery: a predictive model of blood conservation for transfusion avoidance in mainstream populations.
Can there be a place for intraoperative salvaged blood in spine tumor surgery?
Use of intraoperative cell-salvage for autologous blood transfusions in metastatic spine tumour surgery: a systematic review.
Metastatic efficiency of tumour cells can be impaired by intraoperative cell salvage process: truth or conjecture?
A prospective randomized study comparing two techniques of perioperative blood conservation: isovolemic hemodilution and hypervolemic hemodilution.
Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass surgery.
The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer.
Acute normovolemic hemodilution.
Acute normovolemic hemodilution, intraoperative cell salvage and PulseCO hemodynamic monitoring in a Jehovah's Witness with placenta percreta.
Intraoperative cell salvage during radical cystectomy does not affect long-term survival.
Acute normovolemic hemodilution is safe in neurosurgery.
Intraoperative cell salvage in radical prostatectomy does not appear to increase long-term biochemical recurrence, metastases, or mortality.
Impaired red blood cell deformability after transfusion of stored allogeneic blood but not autologous salvaged blood in cardiac surgery patients.
The effect of acute normovolemic hemodilution and acute hypervolemic hemodilution on coagulation and allogeneic transfusion.
Is cell salvage safe in liver resection? A pilot study.
Acute normovolemic hemodilution.
Perioperative management including dual cell salvage in a Jehovah's Witness patient undergoing major urological surgery.
Intra-operative cell salvage in South Africa: feasible, beneficial and economical.
Should intraoperative cell-salvaged blood be used in patients with suspected or known malignancy?
Blood salvage and cancer surgery: a meta-analysis of available studies.
Предоперацонная гиперволемическая гемодилюция 6% гидроксиэтил-крахмалом 130/0,4 (HES 130/0,4) как способ сокращения потребности в трансфузии донорской крови. [Preoperative hypervolemic hemodilution with 6% hydroxyethyl starch 130/0,4 (HES 130/ 0.4) solution as a way of reducing needs for donor blood transfusion.] [Russian, English abstract]
血液回収法
急性等容量性血液希釈
麻酔学的血液温存法
Greater peripheral blood flow but less bleeding with propofol versus sevoflurane during spine surgery: a possible physiologic model?
Controlled hypotension: a guide to drug choice.
Controlled hypotension for spinal surgery.
Magnesium sulphate as a technique of hypotensive anaesthesia.
Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study.
The safety of controlled hypotension for shoulder arthroscopy in the beach-chair position.
The effect of neuraxial blocks on surgical blood loss and blood transfusion requirements: a meta-analysis.
Influence of controlled hypotension versus normotension on amount of blood loss during breast reduction.
A comparison of neuraxial block versus general anesthesia for elective total hip replacement: a meta-analysis.
Comparison of outcomes of using spinal versus general anesthesia in total hip arthroplasty.
Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: preliminary results of a randomized controlled trial.
Comparison of hypotensive epidural anaesthesia and spinal anaesthesia on blood loss and coagulation during and after total hip arthroplasty.
Induced hypotension with epidural/general anesthesia reduces transfusion in radical prostate surgery.
Laparoscopic and robotic partial nephrectomy with controlled hypotensive anesthesia to avoid hilar clamping: feasibility, safety and perioperative functional outcomes.
Anaesthesia for hip fracture surgery in adults.
Deliberate hypotension in orthopedic surgery reduces blood loss and transfusion requirements: a meta-analysis of randomized controlled trials.
Does neuraxial anesthesia reduce intraoperative blood loss? A meta-analysis.
Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials.
Comparative perioperative outcomes associated with neuraxial versus general anesthesia for simultaneous bilateral total knee arthroplasty.
High Le Fort I and bilateral split sagittal osteotomy in Crouzon syndrome.
低血圧法
局所麻酔
医原性貧血を避けるための採血量の制限
Comparison of structured use of routine laboratory tests or near-patient assessment with clinical judgement in the management of bleeding after cardiac surgery.
Savoring every drop—vampire or mosquito?
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study.
Diagnostic blood loss from phlebotomy and hospital-acquired anemia during acute myocardial infarction.
Surgical vampires and rising health care expenditure: reducing the cost of daily phlebotomy.
Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients.
術後貧血の管理
Recombinant human erythropoietin therapy in critically ill Jehovah's Witnesses.
Severe acute anemia after liver transplantation in an elderly Jehovah's Witness treated with high-dose erythropoietin and ferric carboxymaltose: a case report.
Recombinant human erythropoietin in severe anaemia: issues of dosing and duration.
Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized, double-blind, placebo-controlled trial.
The role of erythropoietin therapy in the critically ill.
Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317].
Intravenous ferric carboxymaltose versus standard care in the management of postoperative anaemia: a prospective, open-label, randomised controlled trial.
Safety of off-label erythropoiesis stimulating agents in critically ill patients: a meta-analysis.
An international consensus statement on the management of postoperative anaemia after major surgical procedures.
How do we treat life-threatening anemia in a Jehovah's Witness patient?
Recombinant human erythropoietin use in a critically ill Jehovah's Witness after cardiac surgery.
Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery.
Life-threatening postoperative blood loss in a Jehovah's Witness, treated with high-dose erythropoietin.
Transfusion-free management of gastrointestinal bleeding: the experience of a Bloodless Institute.
Efficacy of recombinant human erythropoietin in critically ill patients admitted to a long-term acute care facility: a randomized, double-blind, placebo-controlled trial.
患者の貧血に対する許容力の最適化
The influence of volume management on outcome.
Hyperbaric oxygen reverses organ dysfunction in severe anemia.
Management of a Jehovah's Witness patient with sepsis and profuse bleeding after emergency coronary artery bypass graft surgery: rethinking the critical threshold of oxygen delivery.
Hyperoxic ventilation at the critical haematocrit.
Prophylactic hypothermia and neuromuscular blockade to limit myocardial oxygen demand in a critically anemic Jehovah's Witness after emergency surgery.
Pillar III—optimisation of anaemia tolerance.
Norepinephrine increases tolerance to acute anemia.
Transfusion-free management of gastrointestinal bleeding: the experience of a Bloodless Institute.
等容量性貧血の許容
Liberal or restrictive transfusion in high-risk patients after hip surgery.
Patient blood management: a patient-orientated approach to blood replacement with the goal of reducing anemia, blood loss and the need for blood transfusion in elective surgery.
Restrictive blood transfusion practices are associated with improved patient outcomes.
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.
Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis.
Transfusion strategies for patients in pediatric intensive care units.
Anemia and perioperative red blood cell transfusion: a matter of tolerance.
Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients?
Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury.
Pillar III—optimisation of anaemia tolerance.
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review.
Mortality and morbidity in non-transfusable and transfusable patients: a systematic review and meta-analysis.
大量出血の有害作用
The beneficial effects of minimizing blood loss in pancreatoduodenectomy.
輸血のリスクと不確実性
Blood transfusion and cancer surgery outcomes: a continued reason for concern.
Surgical outcomes and transfusion of minimal amounts of blood in the operating room.
Adverse blood transfusion outcomes: establishing causation.
Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting.
Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature.
Survival rate changes with transfusion of blood products during liver transplantation.
Emerging infectious disease agents and their potential threat to transfusion safety.
Current perspectives in transfusion-transmitted infectious diseases: emerging and re-emerging infections.
臨床成績
Peri-operative blood transfusion increases length of hospital stay and number of postoperative complications in non-cardiac surgical patients.
Association between the use of blood components and the five-year mortality after liver transplant. [Associação entre Uso de Hemocomponentes e Mortalidade em Cinco Anos após Transplante Hepático.] [English, Portuguese]
How good patient blood management leads to excellent outcomes in Jehovah's Witness patients undergoing cardiac surgery.
Methods of bloodless care, clinical outcomes, and costs for adult patients who decline allogeneic transfusions.
Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Association between intraoperative blood transfusion and mortality and morbidity in patients undergoing noncardiac surgery.
Restrictive blood transfusion practices are associated with improved patient outcomes.
Intraoperative cardiac arrests in adults undergoing noncardiac surgery: incidence, risk factors, and survival outcome.
"Bloodless" neurosurgery among Jehovah's Witnesses: a comparison with matched concurrent controls.
Review article: Risks of anemia and related management strategies: can perioperative blood management improve patient safety?
Cardiac surgery in Jehovah's Witness patients: ten-year experience.
The impact of blood conservation on outcomes in cardiac surgery: is it safe and effective?
Outcome of patients who refuse transfusion after cardiac surgery: a natural experiment with severe blood conservation.
Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery.
Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis.
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review.
Mortality and morbidity in non-transfusable and transfusable patients: a systematic review and meta-analysis.
Blood-management programs: a clinical and administrative model with program implementation strategies.
Implementation of a comprehensive patient blood management program for hospitalized patients at a large united states medical center.
Safety and efficacy of methods for reducing perioperative allogeneic transfusion: a critical review of the literature.
経済効果
Cost-effectiveness of cell salvage and alternative methods of minimising perioperative allogeneic blood transfusion: a systematic review and economic model.
Estimating the epidemiological and economic impact of implementing preoperative anaemia measures in the German healthcare system: the health economic footprint of patient blood management.
Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
Economic considerations on transfusion medicine and patient blood management.
Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery.
Blood product conservation is associated with improved outcomes and reduced costs after cardiac surgery.
From blood transfusion to patient blood management: a new paradigm for patient care and cost assessment of blood transfusion practice.
Safety, cost savings, simplicity back broader use of bloodless surgery.
Associations between preoperative anaemia and hospital costs following major abdominal surgery: cohort study.
Effects of intravenous iron combined with low-dose recombinant human erythropoietin on transfusion requirements in iron-deficient patients undergoing bilateral total knee replacement arthroplasty.
ONTraC: a 20-year history of a successfully coordinated provincewide patient blood management program: Lessons learned and goals achieved.
A prospective study investigating the cost effectiveness of intraoperative blood salvage during liver transplantation.
Effective reduction of blood product use in a community teaching hospital: when less is more.
Prospective monitoring of plasma and platelet transfusions in a large teaching hospital results in significant cost reduction.
Activity-based costs of blood transfusions in surgical patients at four hospitals.
Intra-operative cell salvage in South Africa: feasible, beneficial and economical.
Randomized trial