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Abrishami A, Chung F, Wong J.

Fuente‎: Can J Anaesth 2009;56(3):202-12.

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Can topical application of tranexamic acid reduce blood loss in thoracic surgery? A prospective randomised double blind investigation. (abre una nueva ventana)

Dell'Amore A, Caroli G, Nizar A, Cassanelli N, Luciano G, Greco D, Dolci G, Bini A, Stella F.

Fuente‎: Heart Lung Circ 2012;21(11):706-10.

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Can local application of tranexamic acid reduce post-coronary bypass surgery blood loss? A randomized controlled trial. (abre una nueva ventana)

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Fuente‎: J Cardiothorac Surg 2009;4:25.

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Current status of pharmacologic therapies in patient blood management. (abre una nueva ventana)

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Fuente‎: Anesth Analg 2013;116(1):15-34.

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The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: a randomized, double-blind, placebo-controlled, noninferiority trial. (abre una nueva ventana)

Greilich PE, Jessen ME, Satyanarayana N, Whitten CW, Nuttall GA, Beckham JM, Wall MH, Butterworth JF.

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Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin. (abre una nueva ventana)

Howell N, Senanayake E, Freemantle N, Pagano D.

Fuente‎: J Thorac Cardiovasc Surg 2013;145(1):234-40.

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The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. (abre una nueva ventana)

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Fuente‎: Anesth Analg 2010;110(1):21-9.

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Comparative evaluation of the effects of tranexamic acid and low-dose aprotinin on post-valvular heart surgery bleeding and allogenic transfusion. (abre una nueva ventana)

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Fuente‎: Interact Cardiovasc Thorac Surg 2012;15(1):23-7.

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A randomized trial of tranexamic acid in combination with cell salvage plus a meta-analysis of randomized trials evaluating tranexamic acid in off-pump coronary artery bypass grafting. (abre una nueva ventana)

Murphy GJ, Mango E, Lucchetti V, Battaglia F, Catapano D, Rogers CA, Angelini GD.

Fuente‎: J Thorac Cardiovasc Surg 2006;132(3):475-80, 480.e1-8.

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Tranexamic acid in patients undergoing coronary-artery surgery. (abre una nueva ventana)

Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussières JS, McGuinness S, Byrne K, Chan MT, Landoni G, Wallace S, ATACAS Investigators of the ANZCA Clinical Trials Network

Fuente‎: N Engl J Med 2017;376(2):136-48.

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Aprotinin for patients exposed to clopidogrel before off-pump coronary bypass. (abre una nueva ventana)

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Fuente‎: Asian Cardiovasc Thorac Ann 2008;16(6):483-7.

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Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting: a multicenter randomized trial. (abre una nueva ventana)

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Effect of high- vs low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery: The OPTIMAL randomized clinical trial. (abre una nueva ventana)

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Tranexamic acid reduces blood loss after off-pump coronary surgery: a prospective, randomized, double-blind, placebo-controlled study. (abre una nueva ventana)

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Effects of aprotinin on short-term and long-term outcomes after coronary artery bypass grafting surgery. (abre una nueva ventana)

Wang X, Zheng Z, Ao H, Zhang S, Wang Y, Zhang H, Hu S.

Fuente‎: Ann Thorac Surg 2010;89(5):1489-95.

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Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study. (abre una nueva ventana)

Øvrum E, Tangen G, Tølløfsrud S, Ringdal MA, Øystese R, Istad R.

Fuente‎: Interact Cardiovasc Thorac Surg 2010;10(4):545-8.

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Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa? (abre una nueva ventana)

Ballen J, Raabe M, Muirhead B.

Fuente‎: Can J Anaesth 2006;53(4):353-6.

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Use of recombinant activated factor VII for refractory after lung transplant bleeding as an effective strategy to restrict blood transfusion and associated complications. (abre una nueva ventana)

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Fuente‎: Transfusion 2013;53(4):798-804.

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Recombinant activated factor VII in cardiac surgery: experience from the Australian and New Zealand Haemostasis Registry. (abre una nueva ventana)

Dunkley S, Phillips L, McCall P, Brereton J, Lindeman R, Jankelowitz G, Cameron P.

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Repeat cardiac surgery in a Jehovah's Witness patient with thrombocytopenia. (abre una nueva ventana)

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Fuente‎: Can J Cardiol 2011;27(6):869.e7-8.

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Off-label use of recombinant activated factor VII for cardiac surgical bleeding. (abre una nueva ventana)

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Fuente‎: Anesthesiology. 2023 1;139(2):197-210.

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Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery. (abre una nueva ventana)

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Fuente‎: Circulation 2009;120(1):21-7.

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Intraoperative use of recombinant activated factor VII during complex aortic surgery. (abre una nueva ventana)

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Fuente‎: J Thorac Cardiovasc Surg 2012;143(5):1198-204.

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Off-label use of recombinant human factor VIIa. (abre una nueva ventana)

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Off-label use of recombinant activated factor VII in intractable haemorrhage after cardiovascular surgery: an observational study of practices in 23 French cardiac centres (2005-7). (abre una nueva ventana)

Hacquard M, Durand M, Lecompte T, Boini S, Briançon S, Carteaux JP.

Fuente‎: Eur J Cardiothorac Surg 2011;40(6):1320-7.

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Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery. (abre una nueva ventana)

Karkouti K, Beattie WS, Arellano R, Aye T, Bussieres JS, Callum JL, Cheng D, Heinrich L, Kent B, Lee TW, MacAdams C, Mazer CD, Muirhead B, Rochon AG, Rubens FD, Sawchuk C, Wang S, Waters T, Wong BI, Yau TM.

Fuente‎: Circulation 2008;118(4):331-8.

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Role of recombinant factor VIIa in the treatment of intractable bleeding in vascular surgery. (abre una nueva ventana)

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Use of activated recombinant factor VII in severe bleeding—evidence for efficacy and safety in trauma, postpartum hemorrhage, cardiac surgery, and gastrointestinal bleeding. (abre una nueva ventana)

Lau P, Ong V, Tan WT, Koh PL, Hartman M.

Fuente‎: Transfus Med Hemother 2012;39(2):139-50.

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Recombinant activated factor VII for postoperative hemorrhage following repair of acute type A aortic dissection. (abre una nueva ventana)

Lehr EJ, Alford TJ, Wang SH.

Fuente‎: Heart Surg Forum 2010;13(5):E275-9.

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Recombinant factor VIIa treatment of severe bleeding in cardiac surgery patients: a retrospective analysis of dosing, efficacy, and safety outcomes. (abre una nueva ventana)

Masud F, Bostan F, Chi E, Pass SE, Samir H, Stuebing K, Liebl MG.

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Recombinant activated factor VII significantly reduces transfusion requirements in cardiothoracic surgery. (abre una nueva ventana)

Omar HR, Enten G, Karlnoski R, Ching YH, Mangar D, Camporesi EM.

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Hemostatic management of severe thrombocytopenia in a patient undergoing pulmonic valve replacement. (abre una nueva ventana)

Tanaka KA, Li P, McHugh SM, Subramaniam K.

Fuente‎: A A Case Rep 2015;5(1):3-5.

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Treatment of excessive bleeding in Jehovah's Witness patients after cardiac surgery with recombinant factor VIIa (Novoseven®). (abre una nueva ventana)

Tanaka KA, Waly AA, Cooper WA, Levy JH.

Fuente‎: Anesthesiology 2003;98(6):1513-5.

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Recombinant activated factor VII in cardiac surgery: a systematic review. (abre una nueva ventana)

Warren O, Mandal K, Hadjianastassiou V, Knowlton L, Panesar S, John K, Darzi A, Athanasiou T.

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Reduced use of allogeneic platelets through high-yield perioperative autologous plateletpheresis and reinfusion. (abre una nueva ventana)

Alberts M, Bandarenko N, Gaca J, Lockhart E, Milano C, Alexander S, Linder D, Lombard FW, Welsby IJ.

Fuente‎: Transfusion 2014;54(5):1348-57.

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Use of prothrombin complex concentrate for excessive bleeding after cardiac surgery. (abre una nueva ventana)

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Fuente‎: Interact Cardiovasc Thorac Surg 2012;15(3):382-9.

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Reducing blood transfusion in aortic surgery: a novel approach. (abre una nueva ventana)

Birla R, Nawaytou O, Shaw M, Jackson A, Mills K, Kuduvalli M, Field M, Agarwal S

Fuente‎: Ann Thorac Surg 2019;108(5):1369-75.

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Prophylactic use of factor IX concentrate in a Jehovah's Witness patient. (abre una nueva ventana)

Bolliger D, Sreeram G, Duncan A, Molinaro RJ, Szlam F, Chen EP, Tanaka KA.

Fuente‎: Ann Thorac Surg 2009;88(5):1666-8.

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Safety and efficacy of prothrombin complex concentrate as first-line treatment in bleeding after cardiac surgery. (abre una nueva ventana)

Cappabianca G, Mariscalco G, Biancari F, Maselli D, Papesso F, Cottini M, Crosta S, Banescu S, Ahmed AB, Beghi C.

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Bloodless orthotopic heart transplantation in a Jehovah's Witness. (abre una nueva ventana)

Dallas T, Welsby I, Bottiger B, Milano C, Daneshmand M, Guinn N.

Fuente‎: A A Case Rep 2015;4(10):140-2.

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State of the art - how I manage coagulopathy in cardiac surgery patients. (abre una nueva ventana)

Davidson S.

Fuente‎: Br J Haematol 2014;164(6):779-89.

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First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (abre una nueva ventana)

Görlinger K, Dirkmann D, Hanke AA, Kamler M, Kottenberg E, Thielmann M, Jakob H, Peters J.

Fuente‎: Anesthesiology 2011;115(6):1179-91.

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Comparison of 4-factor prothrombin complex concentrate with frozen plasma for management of hemorrhage during and after cardiac surgery: a randomized pilot trial. (abre una nueva ventana)

Karkouti K, Bartoszko J, Grewal D, Bingley C, Armali C, Carroll J, Hucke HP, Kron A, McCluskey SA, Rao V, Callum J

Fuente‎: JAMA Netw Open 2021;4(4):e213936.

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Prothrombin complex concentrate vs frozen plasma for coagulopathic bleeding in cardiac surgery: the FARES-II multicenter randomized clinical trial. (abre una nueva ventana)

Karkouti K, Callum JL, Bartoszko J, Tanaka KA, Knaub S, Brar S, Ghadimi K, Rochon A, Mullane D, Couture EJ, Lin Y, Harle C, Zeller M, Tran DTT, Solomon C, Rao V, Law M, Butt AL, Chen EP, Martins MR, Saha T, Shih AW, Vézina MC, Moussa F, Pereira Cezar Zamper R, Syed S, Buyukdere H, Werner S, Grewal D, Wong D, Vandyck KB, Tanzola R, Hughes B, Royer O, Wong S, Levy JH; FARES-II Study Group

Fuente‎: JAMA 2025;333(20):1781-92.

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Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study. (abre una nueva ventana)

Karlsson M, Ternström L, Hyllner M, Baghaei F, Flinck A, Skrtic S, Jeppsson A.

Fuente‎: Thromb Haemost 2009;102(1):137-44.

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Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: results from a randomized, placebo-controlled trial. (abre una nueva ventana)

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Fuente‎: J Thorac Cardiovasc Surg 2013;145(3 Suppl):S178-85.

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Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial. (abre una nueva ventana)

Rahe-Meyer N, Solomon C, Hanke A, Schmidt DS, Knoerzer D, Hochleitner G, Sørensen B, Hagl C, Pichlmaier M.

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Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery. (abre una nueva ventana)

Ranucci M, Baryshnikova E, Crapelli GB, Rahe-Meyer N, Menicanti L, Frigiola A; Surgical Clinical Outcome REsearch (SCORE) Group.

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Fibrinogen supplementation after cardiac surgery: insights from the zero-plasma trial (ZEPLAST). (abre una nueva ventana)

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Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate. (abre una nueva ventana)

Robblee JA, Wilkes PR, Dickie SJ, Rubens FD, Bormanis J.

Fuente‎: Can J Anaesth 2012;59(3):299-303.

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Prothrombin complex concentrate in cardiac surgery: a systematic review and meta-analysis. (abre una nueva ventana)

Roman M, Biancari F, Ahmed AB, Agarwal S, Hadjinikolaou L, Al-Sarraf A, Tsang G, Oo AY, Field M, Santini F, Mariscalco G

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Coagulopathy after cardiopulmonary bypass in Jehovah's Witness patients: management of two cases using fractionated components and factor VIIa. (abre una nueva ventana)

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Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products. (abre una nueva ventana)

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Hanke AA, Dellweg C, Kienbaum P, Weber CF, Görlinger K, Rahe-Meyer N.

Fuente‎: Anaesthesia 2010;65(7):688-91.

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A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery. (abre una nueva ventana)

Weber CF, Dietrich W, Spannagl M, Hofstetter C, Jámbor C.

Fuente‎: Anesth Analg 2010;110(3):702-7.

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Armentarium of topical hemostatic products in cardiovascular surgery: an update. (abre una nueva ventana)

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A novel reverse thermosensitive polymer to achieve temporary atraumatic vessel occlusion in infra-popliteal bypasses. (abre una nueva ventana)

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Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011. (abre una nueva ventana)

Menkis AH, Martin J, Cheng DC, Fitzgerald DC, Freedman JJ, Gao C, Koster A, Mackenzie GS, Murphy GJ, Spiess B, Ad N.

Fuente‎: Innovations (Phila) 2012;7(4):229-41.

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Control of troublesome bleeding during repair of acute type A dissection with use of modified rapid deployment hemostat (MRDH). (abre una nueva ventana)

Salerno TA, Gaughan C, Suarez M, Panos AL.

Fuente‎: J Card Surg 2009;24(6):722-4.

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Seyednejad H, Imani M, Jamieson T, Seifalian AM.

Fuente‎: Br J Surg 2008;95(10):1197-225.

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An audit of red cell and blood product use after the institution of thromboelastometry in a cardiac intensive care unit. (abre una nueva ventana)

Anderson L, Quasim I, Soutar R, Steven M, Macfie A, Korte W.

Fuente‎: Transfus Med 2006;16(1):31-9.

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First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (abre una nueva ventana)

Görlinger K, Dirkmann D, Hanke AA, Kamler M, Kottenberg E, Thielmann M, Jakob H, Peters J.

Fuente‎: Anesthesiology 2011;115(6):1179-91.

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Management of hemorrhage in cardiothoracic surgery. (abre una nueva ventana)

Görlinger K, Shore-Lesserson L, Dirkmann D, Hanke AA, Rahe-Meyer N, Tanaka KA.

Fuente‎: J Cardiothorac Vasc Anesth 2013;27(4 Suppl):S20-34.

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Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients. (abre una nueva ventana)

Weber CF, Görlinger K, Meininger D, Herrmann E, Bingold T, Moritz A, Cohn LH, Zacharowski K.

Fuente‎: Anesthesiology 2012;117(3):531-47.

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