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Jehovah’s Witnesses


Neonatal Medicine

Tolerance of Anemia and Thrombocytopenia

Transfusion strategies for patients in pediatric intensive care units.

Lacroix J, Hébert PC, Hutchison JS, Hume HA, Tucci M, Ducruet T, Gauvin F, Collet JP, Toledano BJ, Robillard P, Joffe A, Biarent D, Meert K, Peters MJ; TRIPICU Investigators; Canadian Critical Care Trials Group; Pediatric Acute Lung Injury and Sepsis Investigators Network.

Source‎: N Engl J Med 2007;356(16):1609-19.

Indexed‎: PubMed 17442904

Red blood cell transfusion in newborn infants. [Article in English, French]

Whyte RK, Jefferies AL; Canadian Paediatric Society, Fetus and Newborn Committee.

Source‎: Paediatr Child Health 2014;19(4):213-22.

Indexed‎: PubMed 24855419

Resource implications of adopting a restrictive neonatal blood transfusion policy.

Harrison MC, Pillay S, Joolay Y, Rhoda N, Raban MS, Horn AR, Tooke L.

Source‎: S Afr Med J 2013;103(12):916-7.

Indexed‎: PubMed 24300628

DOI‎: 10.7196/samj.6858

Restrictive versus liberal red blood cell transfusion thresholds in very low birth weight infants: a systematic review and meta-analysis.

Ibrahim M, Ho SKY, Yeo CL.

Source‎: J Paediatr Child Health 2014;50(2):122-30.

Indexed‎: PubMed 24118127

DOI‎: 10.1111/jpc.12409

Unique risks of red blood cell transfusions in very-low-birth-weight neonates: associations between early transfusion and intraventricular hemorrhage and between late transfusion and necrotizing enterocolitis.

Christensen RD, Baer VL, Del Vecchio A, Henry E.

Source‎: J Matern Fetal Neonatal Med 2013;26 Suppl 2:60-3.

Indexed‎: PubMed 24059555

DOI‎: 10.3109/14767058.2013.830495

Restrictive guideline reduces platelet count thresholds for transfusions in very low birth weight preterm infants.

Borges JP, Dos Santos AM, da Cunha DH, Mimica AF, Guinsburg R, Kopelman BI.

Source‎: Vox Sang 2013;104(3):207-13.

Indexed‎: PubMed 23046429

DOI‎: 10.1111/j.1423-0410.2012.01658.x

Neurocognitive profiles of preterm infants randomly assigned to lower or higher hematocrit thresholds for transfusion.

McCoy TE, Conrad AL, Richman LC, Lindgren SD, Nopoulos PC, Bell EF.

Source‎: Child Neuropsychol 2011;17(4):347-67.

Indexed‎: PubMed 21360360

DOI‎: 10.1080/09297049.2010.544647

Implementing a program to improve compliance with neonatal intensive care unit transfusion guidelines was accompanied by a reduction in transfusion rate: a pre-post analysis within a multihospital health care system.

Baer VL, Henry E, Lambert DK, Stoddard RA, Wiedmeier SE, Eggert LD, Ilstrup S, Christensen RD.

Source‎: Transfusion 2011;51(2):264-9.

Indexed‎: PubMed 20723168

DOI‎: 10.1111/j.1537-2995.2010.02823.x

Neurodevelopmental outcome of extremely low birth weight infants randomly assigned to restrictive or liberal hemoglobin thresholds for blood transfusion.

Whyte RK, Kirpalani H, Asztalos EV, Andersen C, Blajchman M, Heddle N, Lacorte M, Robertson CM, Clarke MC, Vincer MJ, Doyle LW, Roberts RS; for the PINTOS Study Group.

Source‎: Pediatrics 2009;123(1):207-13.

Indexed‎: PubMed 19117884

DOI‎: 10.1542/peds.2008-0338

The premature infants in need of transfusion (PINT) study: A randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants.

Kirpalani H, Whyte RK, Andersen C, Asztalos EV, Heddle N, Blajchman MA, Peliowski A, Rios A, Lacorte M, Connelly R, Barrington K, Roberts RS; PINT Investigators.

Source‎: J Pediatr 2006;149(3):301-7.

Indexed‎: PubMed 16939737

The medical section of is designed as an informational resource primarily for use by clinicians and other health-care professionals. It provides neither medical advice nor treatment recommendations and does not substitute for an appropriately qualified health-care provider. The clinical literature cited is not published by Jehovah’s Witnesses, but it outlines transfusion-alternative strategies that might be considered. It is the responsibility of each qualified health-care provider to maintain awareness of new information, discuss options for care, and assist patients in making choices in accord with their medical condition, wishes, values, and beliefs. Not all listed strategies are appropriate or acceptable to all patients.

Patients: Always seek the advice of your doctor or other qualified health-care provider regarding medical conditions or treatments. Check with a doctor if you suspect you are ill.

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