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Jehovah’s Witnesses


Neonatal Medicine

Management of Hemostasis and Thrombocytopenia

Predicting response to rFVIIa in neonates with intractable bleeding or severe coagulation disturbances.

Gkiougki E, Mitsiakos G, Chatziioannidis E, Papadakis E, Nikolaidis N.

Source‎: J Pediatr Hematol Oncol 2013;35(3):221-6.

Indexed‎: PubMed 23511491

DOI‎: 10.1097/MPH.0b013e318286d27e

Severe thrombocytopenia in the NICU.

Baer VL, Lambert DK, Henry E, Christensen RD.

Source‎: Pediatrics 2009;124(6):e1095-100.

Indexed‎: PubMed 19917581

DOI‎: 10.1542/peds.2009-0582

Use of recombinant factor VIIa for uncontrolled bleeding in neonates after cardiopulmonary bypass.

Guzzetta NA, Huch S, Fernandez JD, Tosone SR, Miller BE.

Source‎: Paediatr Anaesth 2009;19(4):364-70.

Indexed‎: PubMed 19143947

DOI‎: 10.1111/j.1460-9592.2008.02905.x

Do platelet transfusions in the NICU adversely affect survival? Analysis of 1600 thrombocytopenic neonates in a multihospital healthcare system.

Baer VL, Lambert DK, Henry E, Snow GL, Sola-Visner MC, Christensen RD.

Source‎: J Perinatol 2007;27(12):790-6.

Indexed‎: PubMed 17855804

Thrombocytopenia related neonatal outcome in preterms.

Bonifacio L, Petrova A, Nanjundaswamy S, Mehta R.

Source‎: Indian J Pediatr 2007;74(3):269-74.

Indexed‎: PubMed 17401266

Is the use of rFVIIa safe and effective in bleeding neonates? A retrospective series of 8 cases.

Mitsiakos G, Papaioannou G, Giougi E, Karagianni P, Garipidou V, Nikolaidis N.

Source‎: J Pediatr Hematol Oncol 2007;29(3):145-50.

Indexed‎: PubMed 17356391

Recombinant activated factor VII (rFVIIa) treatment in infants with hemorrhage.

Brady KM, Blaine Easley R, Tobias JD.

Source‎: Paediatr Anaesth 2006;16(10):1042-6.

Indexed‎: PubMed 16972833

Successful use of recombinant activated FVII and aminocaproic acid in four neonates with life-threatening hemorrhage.

Grizelj R, Vuković J, Filipović-Grčić B, Šarić D, Luetić T.

Source‎: Blood Coagul Fibrinolysis 2006;17(5):413-5.

Indexed‎: PubMed 16788319

Use of recombinant factor VIIa in infants with severe coagulopathy.

Fontaine MJ, Lazarchick J, Taylor S, Annibale D.

Source‎: J Perinatol 2004;24(5):310-1.

Indexed‎: PubMed 15116125

The medical section of is designed as an informational resource primarily for use by clinicians and other health-care professionals. It provides neither medical advice nor treatment recommendations and does not substitute for an appropriately qualified health-care provider. The clinical literature cited is not published by Jehovah’s Witnesses, but it outlines transfusion-alternative strategies that might be considered. It is the responsibility of each qualified health-care provider to maintain awareness of new information, discuss options for care, and assist patients in making choices in accord with their medical condition, wishes, values, and beliefs. Not all listed strategies are appropriate or acceptable to all patients.

Patients: Always seek the advice of your doctor or other qualified health-care provider regarding medical conditions or treatments. Check with a doctor if you suspect you are ill.

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