Anemia Management | Sickle Cell Disease

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SICKLE CELL DISEASE

Anemia Management

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Anemia Management

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A phase 1b/2 study of the efficacy and safety of combination hydroxyurea and dose-escalated erythropoietin for treatment of anemia in sickle cell disease (ACHiEvE-SCD). (opens new window)

Adeyemo TA, Kiriza N, Oluwole FT, Jelinek M, Jonassaint J, Oluwole O, Saber C, Philips BJ, Akinsanya OJD, Osunkalu VO, DeCastro LM, Novelli EM, Xu JZ

Source‎: Blood 2024;144(Suppl 1):178-9.

Preliminary results with administration of recombinant human erythropoietin in sickle cell/beta-thalassemia patients during pregnancy. (opens new window)

Bourantas K, Makrydimas G, Georgiou J, Tsiara S, Lolis D.

Source‎: Eur J Haematol 1996;56(5):326-8.

On the use of hydroxyurea/erythropoietin combination therapy for sickle cell disease. (opens new window)

el-Hazmi MA, al-Momen A, Kandaswamy S, Huraib S, Harakati M, al-Mohareb F, Warsy AS.

Source‎: Acta Haematol 1995;94(3):128-34.

Combination erythropoietin-hydroxyurea therapy in sickle cell disease: experience from the National Institutes of Health and a literature review. (opens new window)

Little JA, McGowan VR, Kato GJ, Partovi KS, Feld JJ, Maric I, Martyr S, Taylor JG 6th, Machado RF, Heller T, Castro O, Gladwin MT.

Source‎: Haematologica 2006;91(8):1076-83.

Use of erythropoietin in a pregnant Jehovah's Witness with sickle-cell disease. (opens new window)

Tan TL, Ahmad H, Jhavar R, Patel R, Harrison C, Oteng-Ntim E.

Source‎: J Obstet Gynaecol 2007;27(1):82-3.

The use of barbiturate coma as salvage therapy in a postoperative Jehovah's Witness patient with life-threatening anemia. (opens new window)

Wang SW, Badami CD, Deitch EA.

Source‎: Am Surg 2009;75(12):1175-8.

Hospital Liaison Committee (HLC)

Contact local representatives who provide free assistance to clinicians treating Jehovah’s Witnesses.

Medical Information Packets

Subjects include: Clinical strategies for managing hemorrhage and anemia without blood transfusion, the religious and ethical position of Jehovah’s Witnesses on medical therapy, and the services Witnesses offer to the medical community through their worldwide network of Hospital Liaison Committees.

Videos

Treatment options as well as medical and ethical considerations for clinicians who treat Jehovah’s Witnesses.

The medical section of this website is designed as an informational resource primarily for use by clinicians and other health-care professionals. It provides neither medical advice nor treatment recommendations and does not substitute for an appropriately qualified health-care provider. The clinical literature cited is not published by Jehovah’s Witnesses, but it outlines transfusion-alternative strategies that might be considered. It is the responsibility of each qualified health-care provider to maintain awareness of new information, discuss options for care, and assist patients in making choices in accord with their medical condition, wishes, values, and beliefs. Not all listed strategies are appropriate or acceptable to all patients.

Patients: Always seek the advice of your doctor or other qualified health-care provider regarding medical conditions or treatments. Check with a doctor if you suspect you are ill.

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