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Jehovah’s Witnesses


Perioperative Care

Tolerance of Normovolemic Anemia

A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.

Hébert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E; Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group.

Source‎: N Engl J Med 1999;340(6):409-17.

Indexed‎: PubMed 9971864

Pillar III—optimisation of anaemia tolerance.

Meier J, Gombotz H.

Source‎: Best Pract Res Clin Anaesthesiol 2013;27(1):111-9.

Indexed‎: PubMed 23590920

DOI‎: 10.1016/j.bpa.2013.02.005

Transfusion strategies for patients in pediatric intensive care units.

Lacroix J, Hébert PC, Hutchison JS, Hume HA, Tucci M, Ducruet T, Gauvin F, Collet JP, Toledano BJ, Robillard P, Joffe A, Biarent D, Meert K, Peters MJ; TRIPICU Investigators; Canadian Critical Care Trials Group; Pediatric Acute Lung Injury and Sepsis Investigators Network.

Source‎: N Engl J Med 2007;356(16):1609-19.

Indexed‎: PubMed 17442904

Anemia and perioperative red blood cell transfusion: a matter of tolerance.

Madjdpour C, Spahn DR, Weiskopf RB.

Source‎: Crit Care Med 2006;34(5 Suppl):S102-8.

Indexed‎: PubMed 16617252

Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis.

Holst LB, Petersen MW, Haase N, Perner A, Wetterslev J.

Source‎: BMJ 2015;350:h1354.

Indexed‎: PubMed 25805204

DOI‎: 10.1136/bmj.h1354

Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.

Roubinian NH, Escobar GJ, Liu V, Swain BE, Gardner MN, Kipnis P, Triulzi DJ, Gottschall JL, Wu Y, Carson JL, Kleinman SH, Murphy EL; NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III).

Source‎: Transfusion 2014;54(10 Pt 2):2678-86.

Indexed‎: PubMed 25135770

DOI‎: 10.1111/trf.12825

Restrictive blood transfusion practices are associated with improved patient outcomes.

Goodnough LT, Maggio P, Hadhazy E, Shieh L, Hernandez-Boussard T, Khari P, Shah N.

Source‎: Transfusion 2014;54(10 Pt 2):2753-9.

Indexed‎: PubMed 24995770

DOI‎: 10.1111/trf.12723

Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review.

Salpeter SR, Buckley JS, Chatterjee S.

Source‎: Am J Med 2014;127(2):124-131.e3.

Indexed‎: PubMed 24331453

DOI‎: 10.1016/j.amjmed.2013.09.017

Liberal or restrictive transfusion in high-risk patients after hip surgery.

Carson JL, Terrin ML, Noveck H, Sanders DW, Chaitman BR, Rhoads GG, Nemo G, Dragert K, Beaupre L, Hildebrand K, Macaulay W, Lewis C, Cook DR, Dobbin G, Zakriya KJ, Apple FS, Horney RA, Magaziner J; FOCUS Investigators.

Source‎: N Engl J Med 2011;365(26):2453-62.

Indexed‎: PubMed 22168590

DOI‎: 10.1056/NEJMoa1012452

Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury.

McIntyre LA, Fergusson DA, Hutchison JS, Pagliarello G, Marshall JC, Yetisir E, Hare GM, Hebert PC.

Source‎: Neurocrit Care 2006;5(1):4-9.

Indexed‎: PubMed 16960287

Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients?

McIntyre L, Hébert PC, Wells G, Fergusson D, Marshall J, Yetisir E, Blajchman MJ; Canadian Critical Care Trials Group.

Source‎: J Trauma 2004;57(3):563-8.

Indexed‎: PubMed 15454803

The medical section of is designed as an informational resource primarily for use by clinicians and other health-care professionals. It provides neither medical advice nor treatment recommendations and does not substitute for an appropriately qualified health-care provider. The clinical literature cited is not published by Jehovah’s Witnesses, but it outlines transfusion-alternative strategies that might be considered. It is the responsibility of each qualified health-care provider to maintain awareness of new information, discuss options for care, and assist patients in making choices in accord with their medical condition, wishes, values, and beliefs. Not all listed strategies are appropriate or acceptable to all patients.

Patients: Always seek the advice of your doctor or other qualified health-care provider regarding medical conditions or treatments. Check with a doctor if you suspect you are ill.

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