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Cost-Effectiveness of Blood Transfusion Alternatives

Orthopedic Surgery

Economic impact of tranexamic acid in healthy patients undergoing primary total hip and knee arthroplasty.

Gillette BP, Maradit Kremers H, Duncan CM, Smith HM, Trousdale RT, Pagnano MW, Sierra RJ.

Source‎: J Arthroplasty 2013;28(8 Suppl):137-9.

Indexed‎: PubMed 23886409

DOI‎: 10.1016/j.arth.2013.04.054

Incidence and costs of bleeding-related complications in French hospitals following surgery for various diagnoses.

Ye X, Lafuma A, Torreton E, Arnaud A.

Source‎: BMC Health Serv Res 2013;13(1):186.

Indexed‎: PubMed 23692862

DOI‎: 10.1186/1472-6963-13-186

Clinical and cost effectiveness-related aspects of retransfusion in total hip and knee arthroplasty.

Dobosz B, Dutka J, Dutka L, Maleta P.

Source‎: Ortop Traumatol Rehabil 2012;14(5):421-8.

Indexed‎: PubMed 23208933

DOI‎: 10.5604/15093492.1016367

The cost of post-operative shed blood salvage after total knee arthroplasty: an analysis of 1,093 consecutive procedures.

Muñoz M, Ariza D, Campos A, Martín-Montañez E, Pavía J.

Source‎: Blood Transfus 2013;11(2):260-71.

Indexed‎: PubMed 23149145

DOI‎: 10.2450/2012.0139-12

Hemostatic techniques reduce hospital stay following multilevel posterior cervical spine surgery.

Cho SK, Yi JS, Park MS, Hu G, Zebala LP, Pahys JM, Kang MM, Lee DH, Riew KD.

Source‎: J Bone Joint Surg Am 2012;94(21):1952-8.

Indexed‎: PubMed 23138237

DOI‎: 10.2106/JBJS.K.00632

Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery.

Irisson E, Hémon Y, Pauly V, Parratte S, Argenson JN, Kerbaul F.

Source‎: Orthop Traumatol Surg Res 2012;98(5):477-83.

Indexed‎: PubMed 22854336

DOI‎: 10.1016/j.otsr.2012.05.002

Use of tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement.

Sepah YJ, Umer M, Ahmad T, Nasim F, Chaudhry MU, Umar M.

Source‎: J Orthop Surg Res 2011;6:22.

Indexed‎: PubMed 21600028

DOI‎: 10.1186/1749-799X-6-22

Blood loss control with two doses of tranexamic acid in a multimodal protocol for total knee arthroplasty.

Ortega-Andreu M, Pérez-Chrzanowska H, Figueredo R, Gómez-Barrena E.

Source‎: Open Orthop J 2011;5:44-8.

Indexed‎: PubMed 21552468

DOI‎: 10.2174/1874325001105010044

Effects of intravenous iron combined with low-dose recombinant human erythropoietin on transfusion requirements in iron-deficient patients undergoing bilateral total knee replacement arthroplasty.

Na HS, Shin SY, Hwang JY, Jeon YT, Kim CS, Do SH.

Source‎: Transfusion 2011;51(1):118-24.

Indexed‎: PubMed 20624257

DOI‎: 10.1111/j.1537-2995.2010.02783.x

One intraoperative dose of tranexamic acid for patients having primary hip or knee arthroplasty.

Ralley FE, Berta D, Binns V, Howard J, Naudie DD.

Source‎: Clin Orthop Relat Res 2010;468(7):1905-11.

Indexed‎: PubMed 20063079

DOI‎: 10.1007/s11999-009-1217-8

Effect of epsilon aminocaproic acid on red-cell transfusion requirements in major spinal surgery.

Berenholtz SM, Pham JC, Garrett-Mayer E, Atchison CW, Kostuik JP, Cohen DB, Nundy S, Dorman T, Ness PM, Klag MJ, Pronovost PJ, Kebaish KM.

Source‎: Spine (Phila Pa 1976) 2009;34(19):2096-03.

Indexed‎: PubMed 19730217

DOI‎: 10.1097/BRS.0b013e3181b1fab2

Efficacy and cost-effectiveness of cell saving blood autotransfusion in adult lumbar fusion.

Savvidou C, Chatziioannou SN, Pilichou A, Pneumaticos SG.

Source‎: Transfus Med 2009;19(4):202-6.

Indexed‎: PubMed 19706137

DOI‎: 10.1111/j.1365-3148.2009.00929.x

Transfusion strategy for primary knee and hip arthroplasty: impact of an algorithm to lower transfusion rates and hospital costs.

Martinez V, Monsaingeon-Lion A, Cherif K, Judet T, Chauvin M, Fletcher D.

Source‎: Br J Anaesth 2007;99(6):794-800.

Indexed‎: PubMed 17928302

The effectiveness of reinfusion after total knee replacement. A prospective randomized controlled study.

Zacharopoulos A, Apostolopoulos A, Kyriakidis A.

Source‎: Int Orthop 2007;31(3):303-8.

Indexed‎: PubMed 16810542

A safe, simple and cost-effective protocol for blood transfusion in primary total knee replacement.

Mehra A, Murray J, DeAlwis C.

Source‎: Ann R Coll Surg Engl 2004;86(4):260-2.

Indexed‎: PubMed 15239867

The medical section of is designed as an informational resource primarily for use by clinicians and other health-care professionals. It provides neither medical advice nor treatment recommendations and does not substitute for an appropriately qualified health-care provider. The clinical literature cited is not published by Jehovah’s Witnesses, but it outlines transfusion-alternative strategies that might be considered. It is the responsibility of each qualified health-care provider to maintain awareness of new information, discuss options for care, and assist patients in making choices in accord with their medical condition, wishes, values, and beliefs. Not all listed strategies are appropriate or acceptable to all patients.

Patients: Always seek the advice of your doctor or other qualified health-care provider regarding medical conditions or treatments. Check with a doctor if you suspect you are ill.

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