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Jehovah’s Witnesses


Cost-Effectiveness of Blood Transfusion Alternatives

Cardiothoracic and Vascular Surgery

Blood product conservation is associated with improved outcomes and reduced costs after cardiac surgery.

LaPar DJ, Crosby IK, Ailawadi G, Ad N, Choi E, Spiess BD, Rich JB, Kasirajan V, Fonner E Jr, Kron IL, Speir AM; Investigators for the Virginia Cardiac Surgery Quality Initiative.

Source‎: J Thorac Cardiovasc Surg 2013;145(3):796-804.

Indexed‎: PubMed 23414992

DOI‎: 10.1016/j.jtcvs.2012.12.041

Experience of a network of transfusion coordinators for blood conservation (Ontario Transfusion Coordinators [ONTraC]).

Freedman J, Luke K, Escobar M, Vernich L, Chiavetta JA.

Source‎: Transfusion 2008;48(2):237-50.

Indexed‎: PubMed 18005329

Comprehensive multimodality blood conservation: 100 consecutive CABG operations without transfusion.

Helm RE, Rosengart TK, Gomez M, Klemperer JD, DeBois WJ, Velasco F, Gold JP, Altorki NK, Lang S, Thomas S, Isom OW, Krieger KH.

Source‎: Ann Thorac Surg 1998;65(1):125-36.

Indexed‎: PubMed 9456106

A structured blood conservation programme reduces transfusions and costs in cardiac surgery.

Ternstrӧm L, Hyllner M, Backlund E, Schersten H, Jeppsson A.

Source‎: Interact Cardiovasc Thorac Surg 2014;19(5):788-94.

Indexed‎: PubMed 25125140

DOI‎: 10.1093/icvts/ivu266

Management of blood transfusion in aortic valve surgery: impact of a blood conservation strategy.

Yaffee DW, Smith DE 3rd, Ursomanno PA, Hill FT, Galloway AC, Deanda A, Grossi EA.

Source‎: Ann Thorac Surg 2014;97(1):95-101.

Indexed‎: PubMed 24263014

DOI‎: 10.1016/j.athoracsur.2013.09.057

Clinical and economic outcomes associated with blood transfusions among elderly Americans following coronary artery bypass graft surgery requiring cardiopulmonary bypass.

Ganz ML, Wu N, Rawn J, Pashos CL, Strandberg-Larsen M.

Source‎: Blood Transfus 2014;12 Suppl 1:s90-9.

Indexed‎: PubMed 23399371

DOI‎: 10.2450/2013.0170-12

Intraoperative cell salvage versus allogeneic transfusion during abdominal aortic surgery: clinical and financial outcomes.

Marković M, Davidović L, Savić N, Sindjelić R, Ille T, Dragas M.

Source‎: Vascular 2009;17(2):83-92.

Indexed‎: PubMed 19426638

Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes.

Rao SV, Kaul PR, Liao L, Armstrong PW, Ohman EM, Granger CB, Califf RM, Harrington RA, Eisenstein EL, Mark DB.

Source‎: Am Heart J 2008;155(2):369-74.

Indexed‎: PubMed 18215610

DOI‎: 10.1016/j.ahj.2007.10.014

Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery.

Scott BH, Seifert FC, Grimson R.

Source‎: Ann Card Anaesth 2008;11(1):15-9.

Indexed‎: PubMed 18182754

Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery.

Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD.

Source‎: Circulation 2007;116(22):2544-52.

Indexed‎: PubMed 17998460

Treatment of refractory bleeding after cardiac operations with low-dose recombinant activated factor VII (NovoSeven®): a propensity score analysis.

Gelsomino S, Lorusso R, Romagnoli S, Bevilacqua S, De Cicco G, Billè G, Stefàno P, Gensini GF.

Source‎: Eur J Cardiothorac Surg 2008;33(1):64-71.

Indexed‎: PubMed 17996457

Clinical effects of reverting from leukoreduced to nonleukoreduced blood in cardiac surgery.

Fung MK, Moore K, Ridenour M, Mook W, Triulzi DJ.

Source‎: Transfusion 2006;46(3):386-91.

Indexed‎: PubMed 16533280

Safety, efficacy, and cost of intraoperative cell salvage and autotransfusion after off-pump coronary artery bypass surgery: a randomized trial.

Murphy GJ, Rogers CS, Lansdowne WB, Channon I, Alwair H, Cohen A, Caputo M, Angelini GD.

Source‎: J Thorac Cardiovasc Surg 2005;130(1):20-8.

Indexed‎: PubMed 15999036

The medical section of is designed as an informational resource primarily for use by clinicians and other health-care professionals. It provides neither medical advice nor treatment recommendations and does not substitute for an appropriately qualified health-care provider. The clinical literature cited is not published by Jehovah’s Witnesses, but it outlines transfusion-alternative strategies that might be considered. It is the responsibility of each qualified health-care provider to maintain awareness of new information, discuss options for care, and assist patients in making choices in accord with their medical condition, wishes, values, and beliefs. Not all listed strategies are appropriate or acceptable to all patients.

Patients: Always seek the advice of your doctor or other qualified health-care provider regarding medical conditions or treatments. Check with a doctor if you suspect you are ill.

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